Explore Senior Machine Learning Engineer opportunities at companies building intelligent products and data-driven systems. These experienced professionals design, develop, and deploy machine learning solutions, turning research and business needs into reliable applications. Ladders features vetted professional jobs paying $100,000 or more, helping you find roles aligned with your skills and career goals.
Senior Machine Learning Engineers typically own substantial parts of the machine learning lifecycle, from defining problems and preparing data to training models, deploying services, and monitoring performance. They collaborate with data scientists, software engineers, product teams, and business stakeholders to deliver solutions that are accurate, scalable, maintainable, and useful.
Employers often seek strong programming skills, especially in Python, along with experience in machine learning frameworks, statistical methods, and software engineering practices. Familiarity with cloud platforms, distributed computing, MLOps, model evaluation, and production deployment can be valuable. Senior roles may also call for technical leadership, mentoring, and the ability to explain complex findings to cross-functional teams.
Senior Machine Learning Engineers work across industries such as technology, finance, healthcare, retail, and logistics. Depending on the organization, the role may focus on generative AI, recommendation systems, search, computer vision, natural language processing, forecasting, or fraud detection. Experienced engineers can grow into staff or principal engineering roles, technical management, or specialized AI leadership positions.
Search Senior Machine Learning Engineer jobs on Ladders to discover vetted professional opportunities with salaries of $100,000 or more. Compare roles by responsibilities, required expertise, and growth potential, then identify openings that match your experience in building and operating machine learning systems.
Senior AI/ML Software Engineer (TS/SCI with Polygraph)
$138K - $165K *
Drive innovation in AI/ML software solutions, enhancing performance and reliability. Collaborate with cross-functional teams to integrate state-of-the-art capabilities while adhering to software engin...
4 weeks ago
Senior AI/ML Software Engineer (TS/SCI with Polygraph)
$145K - $175K *
Drive innovation by developing cutting-edge AI/ML software solutions. Collaborate with diverse teams to optimize large language models and enhance system reliability while applying best engineering pr...
4 weeks ago
Tech Lead-Machine Learning Engineer (Agent & Multi-Agent Systems) - AIGC Risk Intelligence
$241K - $456K *
Contribute to the development of advanced AI-driven risk intelligence systems, implementing multi-agent architectures and leading engineering standards to ensure effectiveness in identifying and mitig...
Reposted 4 days ago
ML Engineer, Inference Optimization
$150K - $180K *
Transform inference performance by optimizing cost, speed, and efficiency. Collaborate with research and product teams to ensure scalable, affordable model deployment while measuring cost as a key met...
2 weeks ago
Senior Embedded Software Engineer
$160K - $190K *
Join a team that's shaping the future of embedded systems by developing innovative software for cutting-edge sensors. Collaborate across disciplines to enhance product reliability and performance whil...
3 weeks ago
Senior AI Engineer (Camgian Labs)
$120K - $145K *
Lead innovative AI/ML-driven R&D projects that advance space defense solutions. Collaborate with multidisciplinary teams and clients, guiding junior engineers while tackling complex technical challeng...
Reposted 2 weeks ago
Principal Machine Learning Engineer, Platform Integrity Engineering, Level 7
$276K - $414K *
Shape the future of content safety by designing and scaling machine learning models to combat harmful content. Collaborate across teams to enhance strategies, ensuring a healthy ecosystem while drivin...
2 weeks ago
Principal Machine Learning Engineer, Platform Integrity Engineering, Level 7
$276K - $414K *
Lead the charge in designing and scaling advanced machine learning systems to enhance content safety and moderation, collaborating across teams to drive innovative solutions and uphold regulatory stan...
2 weeks ago
Principal Machine Learning Engineer, Platform Integrity Engineering, Level 7
$276K - $414K *
Drive innovation as you design and scale machine learning systems to enhance content safety and moderation. Collaborate with cross-functional teams to align strategies and ensure compliance while adva...
2 weeks ago
Principal Machine Learning Engineer, Platform Integrity Engineering, Level 7
$276K - $414K *
Drive innovation by designing and scaling machine learning systems to enhance content safety and moderation. Collaborate across teams to align strategies, improve performance, and tackle complex chall...
2 weeks ago
Senior Customer Success Manager, Managed Inference
$190K - $215K *
Champion customer success through strong relationships, technical support, and strategic guidance for AI cloud solutions, ensuring clients maximize value, achieve performance goals, and navigate compl...
Reposted 3 weeks ago
Senior Customer Success Manager, Managed Inference
$190K - $215K *
Empower clients by managing strategic relationships and providing technical guidance in AI and cloud solutions. Drive customer success through performance monitoring, training, and advocacy, ensuring...
3 weeks ago
$91K - $163K *
Optimize and enhance our data architecture by migrating a legacy data warehouse to a modern cloud-based environment, using advanced tools and agile methodologies for seamless data integration and acce...
Reposted today
#Machine Learning Engineer - Generative AI
$114K - $171K *
Drive innovation by designing and deploying advanced AI systems using LLMs and Agentic AI. Collaborate with cross-functional teams to create scalable solutions that enhance enterprise capabilities and...
2 weeks ago
Senior Software Engineer, AI Infrastructure Solutions
$152K - $241K *
Transform engineering workflows by developing AI-driven solutions that enhance GPU validation and launch efficiency. Collaborate across teams to build scalable infrastructure and intelligent automatio...
5 days ago
Senior Software Engineer - AI Infrastructure
$282K - $332K *
Lead the development of cutting-edge AI infrastructure, guiding teams to design scalable services while navigating complexity. Drive tech initiatives, establish best practices, and ensure impactful AI...
4 weeks ago
Senior Software Engineer - AI Infrastructure
$282K - $332K *
Drive the development and operation of cutting-edge AI infrastructure, while leading a dynamic team. Shape technical policies, enhance platform reliability, and innovate solutions that impact mission...
4 weeks ago
Senior Software Engineer - AI Infrastructure
$282K - $332K *
Join a team that's pioneering the future of AI infrastructure, where you'll design and lead the development of scalable systems. This role offers hands-on engineering and vital leadership responsibili...
4 weeks ago
$130K - $170K *
Deliver impactful data solutions by leading model development and analysis. Collaborate across teams to translate business needs into predictive models and AI solutions, while mentoring junior members...
1 week ago
Senior Architect, Model Performance and Post-Training
$224K - $431K *
Engineer cutting-edge performance models for coding tasks, enhancing large language models through empirical analysis and optimization. Collaborate with cross-functional teams to translate insights in...
2 weeks ago
Senior Architect, Model Performance and Post-Training
$224K - $431K *
Empower the future of coding by driving performance modeling and evaluation of advanced language models. Collaborate with cross-functional teams to enhance coding capabilities, optimize training, and...
2 weeks ago
Member of Technical Staff - Post-Training Infrastructure
$150K - $180K *
Develop and enhance reinforcement learning infrastructure for multimodal agents, collaborating with research teams to optimize performance and scalability in training systems across digital and physic...
1 week ago
(General Hire) Machine Learning Engineer Graduate (Performance Monetization) - 2027 Start
$128K - $256K *
Drive the development of innovative monetization platforms, leveraging cutting-edge machine learning techniques to enhance advertising solutions. Collaborate with cross-functional teams to tackle chal...
Reposted 5 days ago
Machine Learning Engineer Graduate (E-Commerce Recommendation/Search Alliance) - 2027 Start (PhD)
$162K - $387K *
Innovate commerce solutions by designing and developing cutting-edge machine learning algorithms that connect merchants and creators, driving efficiency and growth in an engaging shopping ecosystem...
Reposted 1 week ago
Machine Learning Engineer Graduate (E-Commerce Recommendation/Search Alliance) - 2027 Start (PhD)
$153K - $300K *
Accelerate progress at our E-commerce Alliance team, where you will leverage cutting-edge machine learning and AI to enhance the merchant-creator experience, drive commerce growth, and build innovativ...
Reposted 3 weeks ago
What does a Senior Machine Learning Engineer do?
A Senior Machine Learning Engineer builds and operates machine learning systems, including preparing data, developing and evaluating models, deploying them into production, and monitoring their performance. They often guide technical decisions and collaborate with product, data, and engineering teams.
What qualifications are commonly required for Senior Machine Learning Engineer jobs?
Requirements vary, but commonly include strong programming ability, machine learning and statistical knowledge, experience with production software, and familiarity with tools or frameworks used to train and deploy models. Senior positions may also require cloud, MLOps, system design, and mentorship experience.
What industries hire Senior Machine Learning Engineers?
Technology, finance, healthcare, retail, logistics, and many other sectors hire Senior Machine Learning Engineers to develop applications such as recommendations, fraud detection, forecasting, language technologies, and computer vision.
How can I find Senior Machine Learning Engineer jobs paying $100,000 or more?
Use Ladders to explore vetted professional openings with salaries of $100,000 or more. Review each listing's responsibilities, qualifications, and compensation details to find roles that fit your background and goals.