Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Commercial Insurance Account Manager - OCIPs / CCIPs / Builder's Risk
$90K - $130K *
Empower client relationships by managing day-to-day service and renewals, ensuring satisfaction and accuracy in insurance processes for construction and design professionals. Leverage industry experti...
2 weeks ago
Senior Strategic Implementation Specialist - Americas
$110K - $130K *
Lead the charge in managing complex implementations for enterprise clients, ensuring a seamless onboarding experience. Collaborate cross-functionally to drive customer success and optimize the use of...
1 week ago
Mobile Licensed Nursing Home Administrator
$80K - $95K *
Deliver exceptional leadership as an interim Nursing Home Administrator, ensuring compliance and quality care across multiple facilities. Drive operational excellence, mentor teams, and enhance reside...
5 days ago
$150K - $160K *
Drive project success by managing integrated delivery across AI task orders, overseeing multidisciplinary teams, and ensuring adherence to quality standards while maintaining project roadmaps and sche...
3 weeks ago
Oracle EPM Senior Project Manager
$120K - $145K *
Lead Oracle Cloud EPM projects, ensuring timely delivery and high quality. Collaborate with stakeholders and manage resources to achieve project objectives, fostering team success and effective commun...
Reposted 2 weeks ago
Manager of Account Management, Large Group Segment - Cigna Global Health Benefits (GHB) - Remote
$110K - $130K *
Develop strategic leadership for a team managing complex client portfolios, driving retention, growth, and client experience objectives while fostering strong relationships with stakeholders and ensur...
1 week ago
Senior Manager, Financial Close Management
$120K - $145K *
Drive strategic transformation by leading Record-to-Report functions, enhancing service quality, and implementing best practices across Financial Systems Consulting to achieve world-class operational...
1 week ago
Cyber Risk and Compliance Specialist
$95K - $115K *
Unlock potential by leading IT SOX compliance and enhancing global security culture. Balance technical auditing with advocacy, ensuring financial integrity and regulatory adherence while fostering a r...
Reposted 1 week ago
$100K - $120K *
Drive efficiency and scalability in legal operations by optimizing processes, managing technology, and controlling costs. Lead cross-functional projects and enhance compliance initiatives to support t...
5 days ago
Associate Director, Patient Navigator Strategy, US Oncology, Marketing
$156K - $247K *
Transform patient support strategies and services to ensure effective access for patients navigating their treatment journey, fostering innovative solutions and improving overall patient experiences t...
Reposted 4 days ago
$115K - $130K *
Transform the contracting process by managing the lifecycle of agreements, ensuring efficient execution while balancing risk and compliance. Collaborate with cross-functional teams to support business...
3 weeks ago
$81K - $120K *
Accelerate progress at a dynamic organization by leading risk assessments and audits. Collaborate with teams to enhance internal controls and support strategic initiatives, ensuring compliance and eff...
Today
$148K - $263K *
Champion innovative financial solutions by leading complex OneStream implementations. Collaborate with teams to design scalable architectures, optimize performance, and ensure high-quality deliverable...
Today
$148K - $263K *
Architect high-performance OneStream solutions by translating complex requirements into scalable designs. Lead a team of consultants, ensuring technical quality and optimizing integrations while excee...
1 week ago
$138K - $198K *
Innovate financial strategies as a key partner in FP&A, driving insights and accountability across R&D and G&A. Own financial models, forecasts, and planning processes to support strategic decision-ma...
3 weeks ago
Senior Design Principal - Aviation Interior Design
$145K - $228K *
Transform the aviation passenger experience by leading design teams, mentoring talent, and driving innovative solutions from concept to delivery, ensuring excellence in every project while enhancing t...
3 weeks ago
Principle Div Consultant- Medicare Provider Network Strategy - Remote
$92K - $167K *
Drive strategic initiatives in Medicare Advantage provider networks, analyzing data and collaborating with leadership to enhance performance and achieve goals. Lead complex projects from inception to...
3 weeks ago
Account Director, Promotional Medical Education
$100K - $120K *
Partner with us to drive strategic healthcare marketing initiatives. Lead client relationships, oversee peer-to-peer programs, and mentor team members to ensure compliance and achieve results while fo...
Reposted 2 weeks ago
Lead Enterprise Revenue Architect (Customer Success)
$148K - $225K *
Join a team that's transforming revenue operations through AI-driven insights. You'll collaborate with senior leaders, architect workflows, and drive adoption to ensure measurable business outcomes ac...
Reposted 4 weeks ago
Licensed Nursing Home Administrator
$80K - $95K *
Lead a dynamic team in overseeing operations at a 208-bed skilled nursing facility. Drive quality improvement, ensure regulatory compliance, and foster a positive workplace culture while enhancing res...
2 weeks ago
Director of Protection Orders and Records - Office of Court Administator
$112K *
Deliver comprehensive oversight of protection order processes, ensuring operational efficiency and legal compliance while managing staff and enhancing departmental functions in a dynamic court environ...
1 week ago
Business Operations & Program Management Support Analyst - Senior
$140K - $175K *
Unlock strategic program management oversight by analyzing cross-program activities, mitigating risks, and ensuring effective communication of technical progress to stakeholders. Drive mission outcome...
Reposted 1 week ago
$100K - $120K *
Inspire growth as a Direct Sales Leader, guiding teams while managing your own client relationships. Leverage your sales expertise to train others and deliver tailored insurance solutions, ensuring cl...
Today
Scientific Partnership Medical Director
$230K - $300K *
Champion comprehensive medical strategies for oncology across health systems, engaging at C-suite levels. Leverage extensive collaboration to address clinical needs, advancing BeOne Medicines' portfol...
Reposted 2 days ago
Scientific Partnership Medical Director
$299K - $369K *
Unlock your career potential by driving strategic medical partnerships with US health systems in oncology. Collaborate across functions to enhance evidence generation and meet healthcare priorities th...
Reposted 2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.