Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$128K - $178K *

Elevate your career by owning product enablement for go-to-market teams. Design impactful training programs, partner with leaders, and leverage data to ensure sales readiness and drive success in a fa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by leading cross-functional initiatives to enhance caregiver enrollment technology. Drive strategy, optimize user experiences, and leverage data analytics to achieve growth in a dynam...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $140K *

Develop and execute strategic business initiatives, cultivating partnerships and driving revenue growth through market analysis and relationship management. Collaborate with cross-functional teams to...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$105K - $125K *

Engage in a dynamic product role, driving AI-assisted development from concept to delivery. Collaborate with cross-functional teams to enhance workforce analytics, ensuring customer needs shape produc...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $145K *

Champion client success by managing strategic partnerships with mid-sized enterprises. Drive measurable outcomes through relationship management, consultative problem-solving, and cross-functional col...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Join a dynamic team to drive therapist compensation strategies, ensuring clients find the right care quickly. Collaborate cross-functionally to optimize incentives and enhance therapist availability...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$175K - $210K *

Champion the execution of a comprehensive medical affairs plan for renal cancer theranostics, driving cross-functional alignment and strategic initiatives to enhance patient outcomes and advance clini...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$144K - $200K *

Lead the charge in developing a high-performing sales team focused on mid-sized public safety agencies. Drive recruitment, coaching, and team success while leveraging AI tools to enhance sales strateg...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$95K - $125K *

Transform client relations through innovative sales strategies while achieving consistent targets in a dynamic market. Drive growth by effectively managing existing partnerships and exploring new oppo...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$83K - $110K *

Lead operational excellence by managing complex training programs and enhancing processes for a statewide initiative, ensuring effective communication and client engagement while fostering a high-perf...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$75K - $90K *

Transform client relationships by leading digital marketing strategies, driving growth through multichannel initiatives, and ensuring performance outcomes. Collaborate with internal teams to deliver i...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $225K *

Unlock growth by leading strategic partnerships in the CDMO sector. Drive sales, nurture client relationships, and collaborate across teams to enhance market presence and customer satisfaction. Your e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of healthcare by leading complex architectural and facility projects, ensuring optimal client service and regulatory compliance throughout all project phases while guiding multidiscip...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Join a team that's redefining organizational strategy and driving impactful solutions. As a Senior People Partner, you'll collaborate with leadership to align talent priorities with business outcomes...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$200K - $225K *

Lead the charge in developing strategies for client retention and growth, optimizing team performance, and building robust client relationships to enhance customer experiences and achieve revenue targ...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Join a team that analyzes credit policies and develops strategies to enhance lending effectiveness, utilizes data analytics for risk management, and collaborates with stakeholders to drive impactful d...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Accelerate progress at the forefront of pricing strategy and operations. Lead cross-functional teams to innovate pricing models, enhance profitability, and drive market competitiveness while managing...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $235K *

Transform AI/ML systems by leading end-to-end development of innovative solutions. Tackle complex challenges in medical synthesis and help define and deploy advanced features that enhance user experie...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Business Services

$108K - $201K *

Join a dynamic team to drive clinical trials, ensuring compliance and quality. Manage site relationships, monitor trial progress, and collaborate with cross-functional teams to deliver innovative ther...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Collaborate with cross-functional teams to implement and configure innovative solutions on a risk and compliance platform, ensuring customer success through expertise and effective communication in a...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Unlock potential by driving sales strategy and value analysis, partnering with cross-functional teams to enhance proposals, pricing, and contracts. Lead market research and client engagement to optimi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Lead tax strategy and compliance for a multi-entity healthcare business, driving growth and managing risk. Build and scale the tax function while overseeing audits, planning, and team development to s...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Healthcare

$120K - $145K *

Join a dynamic finance team as you oversee financial reporting, manage reconciliations, and enhance accounting processes. Your expertise will ensure compliance with GAAP while supporting audits and op...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $138K *

Optimize financial analysis and reporting by conducting in-depth research, preparing forecasts, and collaborating across departments to enhance business outcomes and drive strategic decision-making...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to empowering clients through tailored insurance solutions. Lead and inspire a sales team while building lasting relationships with business owners, ensuring their needs a...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.