Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$130K - $160K *

Unlock potential by leading global compensation strategies across multiple regions. Collaborate with HR and business leaders to execute merit cycles, benchmark roles, and innovate with AI tools to enh...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $200K *

Join a dynamic team to drive growth in the pharmaceutical sector, leveraging your expertise to build relationships, win new business, and deliver impactful solutions that enhance brand performance and...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$165K - $192K *

Optimize customer engagement through strategic lifecycle marketing. Lead multi-channel initiatives to enhance customer lifetime value, leveraging data-driven insights and performance metrics to shape...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$206K - $276K *

Optimize global site contracting activities for clinical trials, ensuring efficient execution and compliance. Engage cross-functional teams to enhance operational performance and align contracting str...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$98K - $167K *

Innovate within our network security team by leading the engineering and automation of enterprise security platforms. Drive technical excellence and enhance infrastructure management through modern pr...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Drive strategic client relationships and operational excellence for global healthcare accounts, ensuring optimal service delivery and exceeding performance targets through proactive solutions and coll...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $202K *

Drive customer success by serving as a technical expert, guiding implementations and optimizing strategies for Harness AppSec solutions. Collaborate with clients to ensure they achieve maximum value a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K *

Join a dynamic team to oversee complex enterprise implementations, ensuring successful delivery across multiple departments. Leverage AI tools and project management expertise to enhance stakeholder e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$66K - $100K *

Drive quality assurance in automated underwriting for Commercial Lines, evaluating system behavior and outcomes. Collaborate with teams to enhance processes, identify trends, and ensure alignment with...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Engage as a Legal Solutions Architect, bridging legal expertise and product strategy. Collaborate with Sales and Product teams to enhance legal workflows, drive product development, and empower legal...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$135K - $160K *

Join a team that's redefining enterprise sales by leading strategic partnerships with large corporate insurance agencies and major institutions, driving growth through innovative technology solutions...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$136K - $171K *

Pioneer clinical trial excellence by leading operational planning and execution. Collaborate cross-functionally to ensure compliance, quality, and timely delivery of clinical studies while mentoring j...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$84K - $131K *

Engineer innovative web applications by leveraging Java and Spring Boot. Collaborate across teams to implement DevSecOps practices, ensuring secure, efficient delivery while integrating AI capabilitie...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Drive client engagement and solution development in digital banking, leveraging expertise in banking technology and pre-sales. Collaborate with teams to deliver tailored solutions and impactful demons...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$94K - $110K *

Shape financial strategies by providing expert analysis and insights into capital generation. Collaborate with cross-functional teams to enhance reporting and drive process improvements while mentorin...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $120K *

Transform the future of property management by overseeing a diverse portfolio, maximizing asset value, and fostering strong client relationships while driving operational excellence and financial perf...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Real Estate & Construction

$66K - $110K *

Lead and develop a high-performing unit, ensuring accountability and compliance while managing daily operations to meet service goals. Foster team cohesion and drive results through coaching, training...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Transform frontline manager development by leading strategic programs that enhance coaching, deal inspection, and pipeline management. Collaborate cross-functionally to drive consistent team performan...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $112K *

Unlock potential by managing complex billing processes and leading a team to ensure accurate invoicing and exceptional customer service. Collaborate across departments to drive efficiency and implemen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Join a team that's committed to transforming literacy by collaborating with school leaders. Leverage your educational leadership experience in a dynamic role, driving partnerships that foster effectiv...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$154K - $204K *

Champion strategic financial planning and analysis, driving enterprise-wide initiatives and insights. Lead a high-performing team, enhance reporting capabilities, and support executive decision-making...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$150K - $180K *

Transform the Federal landscape by leading enterprise sales efforts, engaging with SES leaders, and driving digital transformation across major accounts. Collaborate with cross-functional teams to ach...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$126K - $170K *

Elevate your career by driving risk selection and profitability in a dynamic Excess Liability Division. Collaborate with clients and internal teams to deliver tailored insurance solutions while mainta...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$82K - $105K *

Transform complex network infrastructures by designing, deploying, and managing solutions for diverse clients. Leverage your expertise to troubleshoot issues, enhance security, and ensure high availab...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Join a team that's driving innovation in transplant advocacy by integrating business development, marketing, and medical expertise. Collaborate with key stakeholders to enhance KOL engagement and mark...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.