Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$150K - $180K *

Accelerate your career by leading a dynamic sales team to drive IT security solutions. Collaborate with clients and partners to enhance sales strategies, mentor talent, and achieve regional objectives...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $171K *

Drive customer success by managing strategic partnerships in hospitality, ensuring seamless onboarding and tailored support. Foster relationships with stakeholders to optimize energy efficiency and en...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Transform regulatory environments by configuring and supporting Veeva Vault RIM systems. Collaborate with clients to ensure compliance and reliability while implementing ongoing managed services and a...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$106K - $160K *

Lead complex contract negotiations and drive strategic supplier relationships. Collaborate with stakeholders to assess risks, develop negotiation strategies, and enhance contracting practices while me...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$250K - $300K *

Champion strategic growth by leading the charge to secure complex health system accounts. Drive transformative deals with hands-on coaching, leveraging deep relationships and expertise to elevate team...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$175K - $210K *

Unlock potential by leading strategic business development initiatives that connect biopharmaceutical executives with tailored commercial solutions. Drive growth through relationship-building and inno...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $200K *

Drive impactful risk and return analysis for property lines, enhancing pricing strategies and capital management. Collaborate with actuarial teams to develop standards and support forecasting efforts...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$108K - $200K *

Unlock your potential by driving risk and return analysis for property lines. Collaborate with actuarial teams to enhance pricing strategies and support forecasting efforts, influencing positive outco...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $139K *

Optimize your career by joining a dynamic Legal Team, supporting complex contracting and intellectual property matters while safeguarding proprietary technology in a fast-paced environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$167K - $300K *

Lead the charge in oncology marketing by developing KOL engagement strategies and insights for individualized therapies. Collaborate cross-functionally to drive brand strategy and launch planning, ens...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $135K *

Drive sophisticated modeling for insurance products and portfolios, enhancing risk-adjusted returns. Utilize advanced analytics and collaborate across functions to innovate and validate models, ensuri...

1 month ago

  •   8 - 10 years exp.  •   Finance & Insurance

$112K - $225K *

Champion the future of risk management by leveraging your actuarial expertise in a remote role focused on regulatory consulting, pricing, reserving, and reinsurance strategies, while advancing your pr...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in managing complex implementations for enterprise clients, ensuring a seamless onboarding experience. Collaborate cross-functionally to drive customer success and optimize the use of...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $160K *

Drive project success by managing integrated delivery across AI task orders, overseeing multidisciplinary teams, and ensuring adherence to quality standards while maintaining project roadmaps and sche...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$190K - $250K *

Launch a transformative Revenue Operations function to drive growth, partnering with leadership to design analytics, forecasting, and operational strategies that enhance performance across sales, mark...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Lead Oracle Cloud EPM projects, ensuring timely delivery and high quality. Collaborate with stakeholders and manage resources to achieve project objectives, fostering team success and effective commun...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Develop strategic leadership for a team managing complex client portfolios, driving retention, growth, and client experience objectives while fostering strong relationships with stakeholders and ensur...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $185K *

Advance your career by managing business immigration cases end-to-end, collaborating with clients and a seasoned attorney. Contribute to innovative AI-driven legal solutions while shaping the future o...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $185K *

Empower innovation by managing business immigration cases, conducting client consultations, and shaping legal practices with AI tools. Join a dynamic startup to redefine immigration law and enhance cl...

Des Moines, IARemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Drive strategic transformation by leading Record-to-Report functions, enhancing service quality, and implementing best practices across Financial Systems Consulting to achieve world-class operational...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $120K *

Drive efficiency and scalability in legal operations by optimizing processes, managing technology, and controlling costs. Lead cross-functional projects and enhance compliance initiatives to support t...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Transportation

$115K - $130K *

Transform the contracting process by managing the lifecycle of agreements, ensuring efficient execution while balancing risk and compliance. Collaborate with cross-functional teams to support business...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$81K - $120K *

Unlock your potential by leading risk assessments and audits, collaborating with teams to enhance internal controls and support strategic initiatives. Drive impactful change while developing your expe...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$148K - $263K *

Champion innovative financial solutions by leading complex OneStream implementations. Collaborate with teams to design scalable architectures, optimize performance, and ensure high-quality deliverable...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$148K - $263K *

Architect high-performance OneStream solutions by translating complex requirements into scalable designs. Lead a team of consultants, ensuring technical quality and optimizing integrations while excee...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.