Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$100K - $120K *

Lead the charge in driving sales growth and customer engagement by managing key accounts and project strategies. Collaborate with cross-functional teams to enhance product positioning and deliver exce...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$325K - $343K *

Lead the charge in shaping the product vision and strategy for consumer panel and behavioral measurement solutions, driving growth through innovative AI-native practices and client collaboration...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$136K - $220K *

Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$146K - $229K *

Drive the AI roadmap and deliver secure, scalable solutions that enhance decision-making and streamline workflows. Lead teams from experimentation to production, ensuring measurable business value and...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$75K - $110K *

Shape the financial landscape by driving month-end close processes, ensuring general ledger accuracy, and enhancing accounting practices in a dynamic, multi-revenue stream environment. Collaborate to...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$92K - $128K *

Transform partnership operations by managing billing, benefit administration, and cross-functional projects. Leverage your organizational skills to enhance member experiences and streamline processes...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$126K - $162K *

Drive project success by leading design and construction phases, managing teams, and ensuring client satisfaction in commercial and mission-critical environments. Collaborate with stakeholders to deli...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$80K - $95K *

Join a team that's dedicated to managing complex litigation claims, overseeing strategy from filing to resolution. Collaborate with defense counsel and clients to ensure effective case management and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$195K - $244K *

Unlock your potential as a Global Regulatory Leader, driving regulatory strategy and submissions for CNS projects. Collaborate with cross-functional teams, mentor junior staff, and ensure compliance w...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$197K - $246K *

Lead the charge in building strategic relationships with national payers, ensuring access and reimbursement for products. Drive initiatives that enhance patient affordability while collaborating with...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Champion exceptional research outcomes by guiding clients through complex projects. Leverage your expertise in methodology and analysis to deliver actionable insights, while collaborating with cross-f...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Champion enablement initiatives across Technical and Sales domains, partnering with experts to define and execute programs. Lead content development, delivery, and continuous improvement efforts to en...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$183K - $228K *

Drive strategic financial insights as a key partner to the go-to-market teams, owning revenue forecasts and investment economics. Collaborate with leadership to shape long-term growth strategies and e...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's driving business growth by developing strong pipelines and relationships with key decision-makers in the education and corporate sectors. Leverage your expertise to expand market pr...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$88K - $105K *

Drive operational excellence by owning the Professional Services intake and workflow governance processes, ensuring efficient request management and seamless team collaboration to enhance service deli...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $180K *

Drive the vision and strategy for API and integration products, ensuring seamless connectivity across systems. Collaborate with cross-functional teams to deliver innovative solutions that enhance cust...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Accelerate your career by driving revenue growth with enterprise clients. Leverage your sales expertise in the fashion industry to build relationships, identify needs, and deliver tailored solutions t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $105K *

Collaborate with us to manage federal government contracts, ensuring compliance and effective execution throughout the contracting lifecycle. Support proposal development, contract administration, and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Staffing

$80K - $95K *

Drive your career forward by overseeing essential accounting activities, ensuring compliance with GAAP and government contracting regulations. Leverage your expertise in financial reporting, general l...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $160K *

Lead strategic life sciences accounts, driving growth and team development while ensuring project success and client satisfaction through strong relationships and innovative solutions...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$92K - $120K *

Advance the compensation function through strategic AI application, enhancing processes and decision-making. Collaborate with stakeholders to modernize systems, ensuring operational excellence and com...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Empower strategic growth by managing key accounts across diverse sectors. Drive revenue, enhance client relationships, and deliver integrated solutions while collaborating with global teams to ensure...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$148K - $193K *

Lead strategic initiatives in fire protection and plumbing engineering, collaborating with senior management to enhance operations, drive client engagement, and implement technology solutions for impr...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Technical Services

$80K - $95K *

Elevate client relationships by identifying new opportunities and nurturing existing accounts. Collaborate with teams to deliver innovative AV solutions while achieving sales goals in a supportive, em...

1 week ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$160K - $200K *

Drive financial excellence as a senior leader, overseeing operations, strategy, and compliance in a dynamic nonprofit environment. Collaborate with executives to shape growth and ensure transparency a...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.