Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$100K - $120K *

Optimize clinical trial management by overseeing planning, execution, and compliance. Collaborate with cross-functional teams to ensure data integrity and drive innovative treatments while resolving c...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Execute clinical trial management activities, ensuring quality outcomes and compliance. Collaborate with cross-functional teams, manage timelines and budgets, and build strong relationships with stake...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Engage with key healthcare clients to drive strategic account management, fostering relationships and delivering tailored solutions across GE HealthCare’s diverse portfolio, while leading cross-functi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$130K - $155K *

Drive the technical strategy for identity governance services, leading a team to enhance identity security across the organization. Collaborate with cross-functional teams to implement SailPoint solut...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$70K - $116K *

Join a team that's dedicated to enhancing Long-Term Disability claims management. Leverage your expertise to guide professionals, analyze trends, and ensure high-quality outcomes while supporting a co...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$107K - $212K *

Transform client risk management by leading internal audits and controls. Collaborate with executives to enhance operational efficiency and compliance, while fostering a dynamic team environment that...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$94K - $124K *

Lead operational excellence by managing our CLM platform, ensuring efficient contract processes and seamless collaboration among stakeholders, vendors, and technology to optimize procurement operation...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Join a team that's dedicated to enhancing compliance excellence through strategic oversight of operations, risk management, and audit processes. Collaborate with leadership to drive regulatory complia...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Shape compliance excellence by overseeing post-closing functions, managing risks, and driving continuous improvement. Collaborate with stakeholders to ensure adherence to regulations and enhance the C...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Manage the full sales cycle to open new mid-market and enterprise accounts, develop cross-sell opportunities, and grow customer relationships through high-value cybersecurity services, ensuring commer...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $95K *

Advance your career by leading multi-team oversight and management in accounting operations across diverse industries. Utilize your expertise in compliance, software integration, and project managemen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$164K - $305K *

Lead the charge in developing strategic relationships with C-suite executives to drive growth, retention, and value realization across complex health systems, ensuring integrated solutions and measura...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Drive new business generation in captive management solutions, focusing on multifamily risk and large P&C alternatives. Build relationships with brokers and multifamily owners while managing the full...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Transform your career with a pivotal role in clinical research, leading oncology studies and collaborating with cross-functional teams to ensure scientific excellence and regulatory compliance while m...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $130K *

Unlock potential by leading the design and optimization of secure cloud-native platforms. Collaborate across teams to enhance software delivery, implement CI/CD pipelines, and drive best practices in...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Join a team that's dedicated to delivering exceptional financial services. This role involves managing accounts payable, payroll, cash management, and month-end reconciliations while collaborating clo...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$180K - $235K *

Drive growth by leveraging your consultative sales expertise to engage higher education leaders, aligning their needs with innovative research solutions while managing client relationships and achievi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$180K - $225K *

Transform the future of auto claims by designing AI agents that enhance decision-making and streamline processes. Join a dynamic team to build innovative solutions that improve efficiency and accuracy...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$116K - $229K *

Join a dynamic team to support ServiceNow HRSD implementations, optimizing processes and collaborating with cross-functional teams to enhance HR service delivery and client experiences across various...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$116K - $229K *

Join a team that's transforming HR service delivery through innovative ServiceNow solutions. As a Senior Consultant, you'll lead implementations, optimize processes, and collaborate with cross-functio...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$93K - $116K *

Empower integrated marketing campaigns with a focus on account-based marketing. Collaborate with Sales to prioritize accounts, align messaging, and drive pipeline growth while managing multi-channel c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $110K *

Join a team that's dedicated to enhancing compliance and operational integrity through thorough audits and evaluations, ensuring adherence to regulations while fostering a culture of continuous improv...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Empower strategic growth by developing and executing multi-year partner strategies. Collaborate with sales and executive teams to enhance alliances, drive revenue, and foster innovation across North A...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$109K - $150K *

Empower employee relations by providing expert guidance, conducting investigations, and developing policies. Collaborate with HR and legal teams to enhance workplace culture and ensure compliance with...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $175K *

Transform cybersecurity professional services by leading delivery execution, ensuring quality, and developing talent. Collaborate with cross-functional teams to enhance service capabilities and drive...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.