Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$118K - $147K *

Drive high-stakes architectural design for complex technology projects, ensuring innovative solutions from concept through execution while collaborating with leading global firms in a multidisciplinar...

United StatesRemote

Reposted 2 weeks ago

  •   15+ years exp.  •   Manufacturing & Automotive

$95K - $115K *

Drive the resolution of complex surety disputes by conducting technical analyses, collaborating with consultants, and advising on construction and claims management, while leading teams to assess risk...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$260K - $265K *

Innovate the future of hospitality services by unifying existing platforms into a cohesive offering. Collaborate with leadership to define, build, and market a new service model that meets client need...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$79K - $153K *

Unlock potential by building strong relationships with executives, co-creating tailored wealth planning solutions. Collaborate with a cross-functional team to address complex financial needs and enhan...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$79K - $153K *

Shape the future of executive wealth planning by building strong relationships with clients. Leverage your expertise to deliver tailored financial solutions, collaborating with a dedicated team to mee...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Champion strategic HR initiatives that drive organizational design, talent development, and change management. Collaborate with senior leaders to enhance employee experience and align workforce planni...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$125K - $155K *

Champion strategic initiatives by connecting breakthrough chemistry with market opportunities. Collaborate across teams to drive government partnerships, proposals, and commercial growth, transforming...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$80K - $95K *

Join a team that's dedicated to transforming data into actionable insights. As a Senior Analyst, you'll tackle complex challenges, support strategic initiatives, and collaborate with experts to enhanc...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$96K - $210K *

Lead personalized financial planning for senior executives, integrating workplace benefits into comprehensive strategies. Drive client engagement and satisfaction while managing relationships and expa...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's driving revenue growth by managing strategic corporate healthcare accounts, optimizing client satisfaction, and delivering measurable outcomes through expert relationship-building a...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Deliver exceptional consulting services by managing client implementations, diagnosing technical issues, and providing tailored solutions. Collaborate with cross-functional teams to ensure seamless in...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Lead and develop a high-performing team to expand behavioral healthcare access. Drive regional referral growth through strategic partnerships, data-driven decision-making, and effective outreach while...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in multidisciplinary design delivery for data center projects, ensuring buildable, cost-effective designs from planning through construction. Collaborate with teams to meet tenant need...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$160K - $200K *

Drive the evolution of dealer marketing solutions by leading product management efforts, overseeing current offerings, and defining a next-gen platform that enhances customer engagement and retention...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$160K - $200K *

Join a team that's redefining operational efficiency by architecting robust internal tools and applying AI to real-world challenges. You'll lead technical direction, drive impactful decisions, and enh...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$180K - $200K *

Accelerate progress at a multinational level by driving the reward and global mobility agenda. Lead the design and governance of compensation structures, ensuring alignment with business needs while p...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Shape the future of corporate governance by executing compliance workflows, managing documentation, and supporting senior legal professionals in a dual-listed public company environment, ensuring time...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$73K - $88K *

Accelerate progress at expanding customer accounts by driving annual recurring revenue and enhancing retention through structured sales strategies and digital engagement, while managing a high-volume...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$192K - $288K *

Join a team that's driving strategic initiatives in Neuroscience and Oncology. In this pivotal role, you'll partner with leadership to enhance operations, manage budgets, and streamline workforce plan...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $175K *

Unlock potential by serving as a strategic advisor to enterprise clients, guiding them through complex stakeholder environments with predictive intelligence and data-driven insights to drive impactful...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Media

$168K - $283K *

Lead the charge in advancing early-stage clinical trials for innovative Orexin-targeted therapies. Collaborate cross-functionally to shape scientific strategy, drive execution, and ensure high-quality...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$153K - $268K *

Transform clinical science in late-stage trials for innovative sleep/wake therapies. Collaborate cross-functionally to ensure compliance, drive recruitment, and deliver high-quality results while shap...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$170K - $200K *

Drive impactful legal strategies by leveraging your expertise in intellectual property and technology transactions. Join a dynamic team to negotiate contracts and advise on legal matters, contributing...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$155K - $259K *

Champion organizational success by leading HR strategies, guiding senior leaders, and fostering an inclusive workplace. Leverage HR expertise to enhance talent management and drive business performanc...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$90K - $120K *

Optimize client financial systems by implementing tailored processes, managing teams, and providing strategic support to dynamic startups. Engage with diverse clients, ensuring effective communication...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.