Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$95K - $115K *

Join a team that's dedicated to enhancing customer success in cybersecurity. Leverage your expertise to build trusted relationships, drive product adoption, and ensure client satisfaction while naviga...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$210K - $256K *

Transform the landscape of data management by leading a multi-year program that integrates governance, risk, and stakeholder alignment across diverse workstreams in a regulated banking environment, en...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Information Technology

$117K - $158K *

Unlock potential by leading complex client engagements, ensuring timely delivery, budget management, and effective resource utilization while navigating challenges in a dynamic environment. Empower te...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Legal & Accounting

$113K - $226K *

Lead the charge in optimizing healthcare processes by bridging strategy and execution. Collaborate with teams to enhance coding workflows, drive change management, and ensure alignment with strategic...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$84K - $105K *

Drive project success by managing client relationships and leading implementation strategies. Collaborate with teams to assess needs, develop plans, and ensure timely delivery while navigating challen...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$84K - $105K *

Deliver exceptional client engagement by managing project success, assessing needs, and developing strategic plans. Lead cross-functional teams to ensure timely and budget-compliant implementations wh...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$236K - $270K *

Drive commercial legal strategies across APAC and the Americas, partnering with cross-functional teams to support growth. Leverage extensive experience in B2B transactions and marketing law to provide...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Consumer Technology

$280K - $406K *

Join us to lead transformative finance initiatives in the utilities sector, advising top executives on FERC accounting and regulatory compliance while driving operational excellence and mentoring high...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Information Technology

$140K - $239K *

Elevate client relationships in the Healthcare sector by driving new business development and managing diverse portfolios. Collaborate with teams to ensure compliance and deliver tailored solutions th...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$170K - $190K *

Elevate student success by leading innovative marketing strategies for a nationwide education program. Drive engagement and growth through collaboration, creativity, and data-driven decision-making wh...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$80K - $110K *

Unlock potential by leading actuarial projects and analyses to help clients manage risks effectively. Collaborate with a dynamic team to apply advanced statistical methods and deliver insightful risk...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Join a team that's dedicated to enhancing clinical operations through strategic site identification and management. Leverage your expertise to build relationships, track project timelines, and contrib...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Elevate client delivery by leading implementation teams, ensuring satisfaction and operational excellence across multiple projects while fostering strong relationships and driving continuous improveme...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Accelerate client success by owning the onboarding and rollout for enterprise clients, ensuring smooth transitions from purchase to sustained usage. Collaborate with cross-functional teams to drive ad...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $145K *

Elevate the future of Life Sciences by driving growth and innovation. Lead a high-performing sales team to secure enterprise partnerships, leveraging SaaS and AI solutions to transform customer experi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$97K - $116K *

Lead the charge in quality assurance by evaluating clinical audits to ensure compliance and accuracy. Utilize your expertise to mentor staff and drive process improvements that elevate the standard of...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$146K - $269K *

Lead a dynamic team in delivering risk advisory services, enhancing client operations through strategic insights and comprehensive audits. Collaborate with executives to identify risks and implement e...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$101K - $197K *

Lead the development and execution of strategic sales initiatives to enhance market share and client relationships within designated therapeutic areas, ensuring alignment with organizational goals and...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Accelerate progress at the forefront of product innovation, leading a team to drive strategy and customer experience for a key transaction management platform while embedding AI to enhance efficiency...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$144K - $195K *

Join a team that's transforming the legal experience by developing innovative web applications. Collaborate with diverse teams, mentor junior engineers, and tackle complex challenges in a dynamic, agi...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Elevate your career by collaborating with cross-functional teams to enhance business operations, streamline processes, and drive value through effective analysis and documentation. Your expertise will...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Lead the creation and enhancement of high-quality technical documentation, collaborating with cross-functional teams to translate complex information into user-friendly content that improves the overa...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$220K - $265K *

Help us drive financial excellence as a strategic partner in Employee Benefits, providing insights and leadership to enhance growth, profitability, and operational efficiency while collaborating with...

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$85K - $100K *

Champion life underwriting transformation initiatives by analyzing requirements, facilitating project lifecycles, and collaborating with cross-functional teams to enhance operational excellence and im...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$105K - $125K *

Lead and oversee Account Management teams, ensuring operational excellence and compliance while fostering staff development and enhancing client relationships in a dynamic remote environment...

RemoteRemote

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.