Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$225K - $295K *

Accelerate progress at the forefront of contract lifecycle management by driving innovation and strategic solutions. Collaborate with sales teams to enhance customer satisfaction and market leadership...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $190K *

Drive strategic growth by managing key Pharma and Biotech accounts, engaging C-suite executives, and leading expansion sales processes. Collaborate cross-functionally to enhance client experiences and...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $110K *

Join a team that's dedicated to supporting disaster recovery efforts. Collaborate with leadership and clients to navigate complex recovery operations, ensuring effective management of multi-billion do...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$94K - $179K *

Lead the charge in managing complex projects from inception to completion, ensuring timely delivery and stakeholder satisfaction while guiding cross-functional teams through the project lifecycle...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$78K - $206K *

Unlock potential by leading clinical performance improvement projects for Medicare Provider Collaboration groups. Collaborate with teams to enhance population health outcomes, focusing on Stars qualit...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$107K - $134K *

Drive innovative actuarial pricing solutions by leading complex projects, enhancing filing processes, and collaborating cross-functionally to align technical insights with strategic goals in a dynamic...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Transform financial operations by leading fund administration, ensuring compliance, and mentoring teams while managing complex investment transactions and audits for venture capital funds...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$170K - $200K *

Champion operational excellence by leading business unit strategies, enhancing performance management, and driving cross-functional collaboration to achieve enterprise goals and scalable solutions...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Transform your career by driving growth in commercial real estate financing. This role focuses on originating and structuring loans while building strong relationships with clients and industry profes...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Transform the accounting function by overseeing monthly closes, ensuring compliance, and managing tax processes. Collaborate with finance leadership to drive accurate reporting and support strategic p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$135K - $180K *

Drive compliance excellence by managing global product projects across diverse markets. Collaborate with teams to ensure adherence to regulations for dietary supplements, foods, cosmetics, and medical...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Reimagine retirement solutions by driving sales in small to mid-sized markets. Collaborate with financial intermediaries to build relationships and achieve company objectives while managing a dynamic...

RemoteRemote

1 month ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Take ownership of automating workflows across teams by building AI agents using Claude and Microsoft Copilot. Collaborate with various departments to identify automation opportunities, ensuring securi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Drive transformational growth by managing critical customer relationships and partnerships. Leverage AI insights to shape enterprise strategies, influence executive decisions, and mentor sales profess...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$97K - $118K *

Lead the charge in developing and executing strategic sales initiatives for large accounts, fostering key relationships to drive long-term revenue growth and market penetration while collaborating acr...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Drive sales performance by managing comprehensive compensation strategies that align with company goals. Collaborate across teams to design and implement effective plans, analyze data trends, and ensu...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Staffing

$195K - $277K *

Drive innovative clinical oncology studies by designing protocols, collaborating with teams, and ensuring compliance with regulations. Leverage expertise to analyze data, support publications, and mai...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Transform the advisor experience by leading a dynamic team focused on growth, retention, and asset management. Drive measurable results through innovative strategies and a robust service model, ensuri...

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$100K - $120K *

Lead a dynamic sales team, mentoring new members while managing your own client relationships. Drive success through effective training and personalized insurance solutions, ensuring client satisfacti...

Reposted yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$102K - $147K *

Accelerate growth by developing strategic relationships with C-level executives to identify and secure new business opportunities, driving the entire sales cycle in a high-stakes environment focused o...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Optimize product performance by analyzing data, managing initiatives, and collaborating with teams. Your insights will shape strategies for Motorcycle, RV, Watercraft, and Classic Car products, drivin...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Manage key capital markets activities, overseeing debt operations, cash flow forecasting, and financial risk management. Collaborate with stakeholders to prepare executive materials and support pensio...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Advance clinical trial success by providing strategic expertise in operations and collaboration. Optimize processes, develop budgets, and drive initiatives to enhance efficiency while ensuring alignme...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Accelerate audit excellence by managing financial and operational audits, ensuring efficiency and compliance while fostering continuous improvement and collaboration across teams to deliver high-quali...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $115K *

Elevate financial accuracy by leading revenue accounting and accounts receivable processes. Own revenue-cycle close activities, collaborate cross-functionally, and drive improvements in a fast-paced e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.