Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$142K - $228K *

Join a team that's shaping the future of corporate governance and compliance! In this role, you'll provide strategic legal guidance, mitigate risks, and ensure adherence to laws, driving operational e...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$164K - $245K *

Transform vendor legal operations by leading negotiations and enhancing processes. Collaborate with cross-functional teams to streamline agreements and empower stakeholders, ensuring efficiency and sc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$115K - $135K *

Drive your career forward by managing a diverse portfolio of high-net-worth clients, delivering expert tax preparation and advisory services while collaborating with financial advisors to maximize cli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $158K *

Champion high-availability database platforms, driving automation and cloud modernization. Collaborate with engineering teams to enhance reliability and performance across hybrid environments, ensurin...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$220K - $250K *

Unlock potential by driving strategic partner relationships and collaborating across teams to enhance solution development, enabling partners to achieve measurable outcomes while promoting business gr...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$85K - $105K *

Champion exceptional client relationships by delivering innovative solutions, managing campaigns, and driving strategic marketing goals to enhance performance and satisfaction for high-value clients i...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Transform financial operations by leading accounting, reporting, and FP&A. Drive efficiency through AI integration, manage audits, and build scalable processes while supporting strategic growth initia...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$100K - $140K *

Champion the proposal process by leading submissions, coordinating resources, and ensuring strategic alignment. Drive improvements in proposal development while fostering collaboration across teams to...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's committed to enhancing environmental, health, and safety standards across multiple sites. Lead audits, provide hands-on support, and drive compliance initiatives while collaborating...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$230K - $345K *

Shape the future of late-stage oncology clinical trials by leading strategic initiatives, ensuring operational excellence, and fostering cross-functional partnerships to drive successful trial executi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$81K - $86K *

Develop and implement clinical services for students and families, collaborating with school staff to enhance mental health support and ensure effective treatment planning and crisis intervention in a...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $125K *

Deliver exceptional customer success through effective engagement, relationship-building, and proactive problem-solving for complex district implementations. Collaborate with teams to ensure portfolio...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Unlock potential by driving transformational sales initiatives and cultivating strategic partnerships. Engage with C-suite stakeholders to shape enterprise revenue and influence market direction throu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$191K - $238K *

Shape the future of oncology by leading medical strategy for prostate cancer projects. Collaborate with cross-functional teams to drive scientific communication and strategic initiatives, ensuring ali...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Empower partner marketing initiatives by developing strategies that drive qualified referrals and pipeline growth across diverse partner ecosystems in North America and EMEA. Collaborate with stakehol...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Unlock compensation strategies by partnering with teams to analyze, model, and deliver data-driven solutions. Drive benchmarking, job architecture, and annual comp cycles to ensure equitable pay pract...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Grow your career with a robust role in executing paid search campaigns while driving performance in a multi-brand environment. Join a dynamic team committed to optimizing revenue through strategic ad...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $150K *

Drive operational excellence in a VP-level role, leading a food manufacturing facility's ramp-up. Oversee production, financial performance, and team development to meet growing customer demand and su...

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$89K - $166K *

Help us drive growth as you lead a team focusing on Commercial Claims, enhancing key relationships and achieving sales objectives while managing strategic accounts and fostering talent development wit...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$150K - $268K *

Drive state and local government relations across 25 states, managing legislative efforts and stakeholder engagement to advance business goals. Collaborate with internal teams and external partners to...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$164K - $246K *

Unlock potential by driving customer transformation and success in strategic accounts. Leverage your leadership skills to enhance value across deployments, ensuring satisfaction and optimizing the ado...

RemoteRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$100K - $120K *

Lead the consolidation of financial models and metrics, partnering with cross-functional teams to deliver actionable insights and support strategic decision-making across the organization...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$127K - $260K *

Transform your career by leading the design and implementation of a comprehensive learning ecosystem for Assurance teams, fostering high-performance and collaboration across the organization to enhanc...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$300K - $325K *

Shape the future of retirement and investment marketing by driving growth, enhancing client engagement, and leading strategic initiatives across multiple business lines. Collaborate with cross-functio...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$100K - $120K *

Engage with senior stakeholders to enhance R&D efficiency in life sciences. Drive proposals, develop strategies, and ensure quality oversight while building networks to support business development an...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.