Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$150K - $180K *
Unlock potential by driving enterprise AI adoption across functions, partnering with leaders to design and implement innovative AI solutions. This role combines architecture, engineering, and strategi...
2 weeks ago
$88K - $110K *
Lead cross-functional projects in Human Resources to enhance employee experience, streamline processes, and ensure effective implementation of strategic initiatives. Partner closely with key stakehold...
Reposted 2 weeks ago
Principal Portfolio Project Manager - Transmitters & Toxic Gas
$110K - $130K *
Lead the charge in managing the lifecycle of product development projects, ensuring timely and budget-friendly delivery while collaborating across teams and addressing technical challenges to meet bus...
2 weeks ago
Biomarkers Senior Research Lab Scientist (Ligand Binding Assays)
$120K - $180K *
Optimize biomarker assay development and validation for clinical trials. Collaborate with cross-functional teams to troubleshoot challenges and present results. Ideal for an independent scientist with...
2 weeks ago
Principal Reactor Physics & Neutronics Engineer
$135K - $160K *
Shape your future in the nuclear energy sector by leading advanced reactor physics and neutronics initiatives. Contribute technical expertise and mentor growth while establishing best practices to dri...
2 weeks ago
$120K - $145K *
Elevate your software engineering career by contributing to mission-critical systems. Collaborate in agile teams to enhance and support the U.S. Navy’s Aegis Weapons System through innovative software...
2 weeks ago
Senior Research Scientist, Cloud AI Research
$174K - $252K *
Empower innovation by conducting foundational agentic research and developing state-of-the-art autonomous AI systems. Collaborate across teams to translate cutting-edge prototypes into scalable soluti...
1 week ago
Senior Manager of Statistical Analysis and Quality Control
$140K - $155K *
Lead and manage statistical analysis and quality control efforts, ensuring data integrity and accuracy while guiding project teams. Engage with complex datasets, implementing rigorous QC standards and...
3 weeks ago
$120K - $145K *
Create innovative atmospheric sensing instruments that meet scientific needs, ensuring reliability and precision. Lead technical development from concept to production, driving project success through...
6 days ago
Staff Process Controls Engineer - Pilot Plant
$110K - $130K *
Lead the development of innovative chemical refining processes and optimize plant operations by overseeing programming, team management, and project execution. Collaborate with cross-functional teams...
1 week ago
Manager, Small Molecule (GMP Lab)
$95K - $115K *
Shape your career as a Manager in our Lab Services Team, overseeing daily operations, ensuring client satisfaction, and driving project success through effective resource management and staff developm...
3 weeks ago
Senior Director - Tech@Lilly MQ
$157K - $231K *
Empower the future of pharmaceutical manufacturing by leading digital strategy initiatives for a new AI-driven facility, optimizing compliance and operational excellence to enhance patient care and dr...
Today
Senior Academic Research Scientist - School of Medicine, Pharmacology
$110K - $130K *
Champion cutting-edge research by leading experimental design and data analysis. Collaborate with CROs, manage major scientific components, and enhance laboratory operations while advancing compounds...
3 weeks ago
Principal Software Engineer, OpenSearch Platform
$104K - $234K *
Transform distributed systems design by leading complex projects across teams to enhance the functionality and reliability of OCI Search Service. Drive innovations in operational excellence, performan...
4 days ago
Senior Project Manager, Commercial Operations
$95K - $115K *
Unlock growth potential by coordinating cross-functional projects, managing timelines, and enhancing operational efficiencies. Collaborate with diverse teams to streamline processes and drive initiati...
3 weeks ago
Senior Project Manager, Commercial Operations
$95K - $115K *
Execute strategic initiatives by coordinating cross-functional teams, managing project timelines, and mitigating risks. Drive operational efficiency and support growth initiatives across various depar...
3 weeks ago
$130K - $160K *
Discover innovative test concepts and execution strategies for Co-Packaged Optics, ensuring precision through hands-on characterization, automation, and collaboration with cross-functional teams to dr...
1 week ago
Program Manager - Technical Operations
$130K - $179K *
Drive program excellence by leading complex Technical Operations initiatives, ensuring strategic alignment and operational effectiveness across multidisciplinary teams for successful pharmaceutical de...
1 week ago
$82K *
Join a team that's dedicated to optimizing laboratory instrumentation and quality systems for polylactic acid (PLA) products. Collaborate with cross-functional teams to ensure reliable results, while...
3 days ago
Process Development Associate Scientist
$90K - $122K *
Join our dynamic team to spearhead formulation and process development studies, collaborating with engineers and scientists to impact drug product commercialization and lifecycle management for biolog...
Today
Process Development Associate Scientist
$90K - $122K *
Lead the charge in developing analytical methods for synthetic molecules. Collaborate with scientists to enhance product quality through innovative solutions, while ensuring compliance with technical...
Today
Program Manager, Technology Partnership Development
$160K - $190K *
Oversee the operational core of business development and licensing efforts, coordinating partnerships, tracking deals, and ensuring patent portfolio alignment for effective deal-making and optimal pro...
6 days ago
Associate Scientist, Biologics Characterization
$103K - $162K *
Lead the charge in biologics characterization and analysis, utilizing mass spectrometry and biophysical methods. Independently plan, execute, and report on experiments, ensuring compliance with regula...
Reposted 2 weeks ago
Sr Manager, Process Engineering
$153K - $199K *
Provide technical leadership for clinical cell therapy manufacturing operations, guiding equipment and automation reliability, supporting technology transfers, and ensuring compliance with regulatory...
6 days ago
Process Development Associate Scientist
$90K - $122K *
Develop manufacturing processes for cell culture and purification, enhancing production yields and robustness. Collaborate in a dynamic team to execute experiments and support regulatory filings while...
Reposted 2 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.