Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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Compensation
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$150K - $180K *

Unlock potential by driving enterprise AI adoption across functions, partnering with leaders to design and implement innovative AI solutions. This role combines architecture, engineering, and strategi...

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$88K - $110K *

Lead cross-functional projects in Human Resources to enhance employee experience, streamline processes, and ensure effective implementation of strategic initiatives. Partner closely with key stakehold...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Lead the charge in managing the lifecycle of product development projects, ensuring timely and budget-friendly delivery while collaborating across teams and addressing technical challenges to meet bus...

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$120K - $180K *

Optimize biomarker assay development and validation for clinical trials. Collaborate with cross-functional teams to troubleshoot challenges and present results. Ideal for an independent scientist with...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Shape your future in the nuclear energy sector by leading advanced reactor physics and neutronics initiatives. Contribute technical expertise and mentor growth while establishing best practices to dri...

2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$120K - $145K *

Elevate your software engineering career by contributing to mission-critical systems. Collaborate in agile teams to enhance and support the U.S. Navy’s Aegis Weapons System through innovative software...

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$174K - $252K *

Empower innovation by conducting foundational agentic research and developing state-of-the-art autonomous AI systems. Collaborate across teams to translate cutting-edge prototypes into scalable soluti...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$140K - $155K *

Lead and manage statistical analysis and quality control efforts, ensuring data integrity and accuracy while guiding project teams. Engage with complex datasets, implementing rigorous QC standards and...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Create innovative atmospheric sensing instruments that meet scientific needs, ensuring reliability and precision. Lead technical development from concept to production, driving project success through...

6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Lead the development of innovative chemical refining processes and optimize plant operations by overseeing programming, team management, and project execution. Collaborate with cross-functional teams...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Shape your career as a Manager in our Lab Services Team, overseeing daily operations, ensuring client satisfaction, and driving project success through effective resource management and staff developm...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$157K - $231K *

Empower the future of pharmaceutical manufacturing by leading digital strategy initiatives for a new AI-driven facility, optimizing compliance and operational excellence to enhance patient care and dr...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion cutting-edge research by leading experimental design and data analysis. Collaborate with CROs, manage major scientific components, and enhance laboratory operations while advancing compounds...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$104K - $234K *

Transform distributed systems design by leading complex projects across teams to enhance the functionality and reliability of OCI Search Service. Drive innovations in operational excellence, performan...

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Unlock growth potential by coordinating cross-functional projects, managing timelines, and enhancing operational efficiencies. Collaborate with diverse teams to streamline processes and drive initiati...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Execute strategic initiatives by coordinating cross-functional teams, managing project timelines, and mitigating risks. Drive operational efficiency and support growth initiatives across various depar...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $160K *

Discover innovative test concepts and execution strategies for Co-Packaged Optics, ensuring precision through hands-on characterization, automation, and collaboration with cross-functional teams to dr...

1 week ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$130K - $179K *

Drive program excellence by leading complex Technical Operations initiatives, ensuring strategic alignment and operational effectiveness across multidisciplinary teams for successful pharmaceutical de...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$82K *

Join a team that's dedicated to optimizing laboratory instrumentation and quality systems for polylactic acid (PLA) products. Collaborate with cross-functional teams to ensure reliable results, while...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $122K *

Join our dynamic team to spearhead formulation and process development studies, collaborating with engineers and scientists to impact drug product commercialization and lifecycle management for biolog...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $122K *

Lead the charge in developing analytical methods for synthetic molecules. Collaborate with scientists to enhance product quality through innovative solutions, while ensuring compliance with technical...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Oversee the operational core of business development and licensing efforts, coordinating partnerships, tracking deals, and ensuring patent portfolio alignment for effective deal-making and optimal pro...

6 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$103K - $162K *

Lead the charge in biologics characterization and analysis, utilizing mass spectrometry and biophysical methods. Independently plan, execute, and report on experiments, ensuring compliance with regula...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$153K - $199K *

Provide technical leadership for clinical cell therapy manufacturing operations, guiding equipment and automation reliability, supporting technology transfers, and ensuring compliance with regulatory...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $122K *

Develop manufacturing processes for cell culture and purification, enhancing production yields and robustness. Collaborate in a dynamic team to execute experiments and support regulatory filings while...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.