Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$130K - $180K *

Grow your career with a leadership role that influences engineering practices, shapes robust architectures, and mentors peers. Drive high performance across complex systems while embracing shared owne...

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Shape the future of ground systems by leading technical engagements and integrating solutions to meet customer needs. Leverage your expertise in engineering to drive product development and ensure top...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$96K - $134K *

Optimize lipid nanoparticle formulations for nucleic acid delivery, advancing both platform innovation and preclinical development through collaborative and independent research efforts in formulation...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$293K - $325K *

Transform experimentation methodologies and drive technical strategy to enhance reliability and usability across teams. Collaborate on statistical rigor, and build scalable solutions to complex challe...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $130K *

Drive impactful supply chain operations across North America, ensuring efficiency and performance. Lead demand planning, sourcing, procurement, and distribution efforts while supporting substantial re...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$228K - $313K *

Lead CMC strategy and execution across multiple emerging modalities, shaping long-term direction while ensuring timely program advancement. Build a high-performing team and manage external CDMO networ...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Lead execution of critical partner programs, enhancing delivery and compliance across banking and payment vendors, while ensuring streamlined communication between teams for faster, scalable outcomes...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$217K - $271K *

Empower quality assurance by providing strategic oversight of GMP compliance across the CMC lifecycle. Collaborate with cross-functional teams to ensure inspection readiness and drive quality objectiv...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$165K - $180K *

Partner with us to design innovative plant concepts for diverse projects. Lead multidisciplinary teams, mentor junior engineers, and ensure compliance with industry standards while driving continuous...

Mississauga, ONIn-Person

Today

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$105K - $206K *

Lead the design and integration of cutting-edge A2PNT solutions while managing program milestones and collaborating with stakeholders to deliver mission-ready capabilities across diverse platforms...

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$90K - $120K *

Lead technical initiatives in specialty adhesives, bridging chemistry, performance, and customer needs to drive product excellence and innovation in industrial bonding applications. Collaborate cross...

4 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$123K - $181K *

Support process safety initiatives by performing risk assessments, developing standards, and providing technical guidance to project teams. Drive compliance and safety within manufacturing operations...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $200K *

Drive advancements in autonomy by designing and enhancing control algorithms. Collaborate with experts to integrate data-driven solutions, optimize vehicle performance, and tackle real-world challenge...

2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$90K - $136K *

Collaborate with cross-functional teams to develop and validate advanced analytical methods for cell therapy products. Your expertise will support the progression from research through regulatory fili...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$157K - $216K *

Accelerate progress at a technology-driven team, leading initiatives to enhance platform reliability and security. Collaborate cross-functionally to prioritize needs and streamline operations while en...

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$79K - $94K *

Provide Process Engineering expertise in a dynamic R&D environment, focusing on innovation and optimization of manufacturing processes. Collaborate with cross-functional teams to enhance product quali...

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$103K - $242K *

Drive innovation and excellence in delivering data engineering solutions using Databricks. Lead and mentor teams to ensure top-tier performance while developing scalable data architectures for complex...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $160K *

Shape the future of SAP Cloud transformations by leading architecture and driving client engagements. As a trusted advisor, influence C-suite decisions and showcase innovative solutions to enhance bus...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $105K *

Join a dynamic team to build relationships and drive revenue growth in the Standards sector, focusing on Reference Materials and Analytical Standards. Collaborate with stakeholders to meet sales targe...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$177K - $329K *

Shape the future of AI by architecting agentic capabilities within a dynamic team, influencing organizational decision-making, and enhancing user experience through innovative B2B Generative AI applic...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$137K - $189K *

Unlock potential by leveraging data insights to drive strategic business decisions. Collaborate with cross-functional teams to transform complex datasets into actionable analytics and visualizations t...

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$84K - $125K *

Collaborate as a bioprocessing expert to accelerate technology adoption and optimize upstream workflows, providing technical leadership and ensuring compliance, performance, and customer success in bi...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$84K - $125K *

Unlock potential by serving as a bioprocessing expert, providing technical leadership and support to biotechnology customers. You'll drive process design and optimization, enhancing performance across...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$84K - $125K *

Collaborate with biotech clients to enhance bioprocessing technology adoption, providing expertise in upstream workflows. Drive process optimization and deliver technical training, ensuring compliance...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$84K - $125K *

Shape the future of bioprocessing by engaging with biotech customers to optimize technology adoption and process design in upstream workflows, providing expert guidance from pre-sales to troubleshooti...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.