Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
(Senior / Principal) Scientist, In Vivo Pharmacology
$125K - $150K *
Engage in the design and execution of mouse studies to evaluate therapeutic candidates, employing pharmacokinetics and safety data to guide decision-making on next steps in research and development...
1 week ago
Principal Scientist, Medicinal Chemistry
$156K - $214K *
Champion innovative medicinal chemistry strategies by leading multidisciplinary teams. Leverage your expertise in organic synthesis and data analysis to optimize lead compounds, mentor talent, and dri...
1 week ago
Senior Scientist, Cell Line Development
$112K - $168K *
Advance your career by driving innovative cell line development and viral packaging, leveraging high-throughput screening and analytics to optimize clone performance, and collaborating with interdisci...
4 days ago
Principal Scientist, Translational Medicine, Neuroscience
$255K - $402K *
Champion innovative therapies as a Principal Scientist in Translational Medicine. Collaborate to lead early clinical development in neuroscience, advancing novel treatments from concept to clinical tr...
3 days ago
Principal Scientist, Translational Medicine, Neuroscience
$255K - $402K *
Transform the landscape of neuroscience therapeutics by leading innovative early clinical development strategies, collaborating with diverse teams to address neurologic and psychiatric disorders, and...
3 days ago
$120K - $145K *
Discover innovative solutions in drug discovery and AI research. Collaborate with top scientists, refine products, and tackle complex biological challenges to drive partner success and improve therape...
2 weeks ago
Principal Scientist (Scientific Director Level)- Nonclinical Drug Safety
$176K - $277K *
Grow your career with a leadership role defining nonclinical drug safety strategies. Collaborate across functions to assess risks, promote innovative thinking, and drive decisions that impact therapeu...
6 days ago
Principal Scientist (Scientific Director Level)- Nonclinical Drug Safety
$176K - $277K *
Deliver innovative drug safety strategies across multiple therapeutic areas, driving cross-functional collaboration from discovery through to regulatory submissions. Lead risk assessments and shape pr...
6 days ago
Principal Scientist (Scientific Director Level)- Nonclinical Drug Safety
$176K - $277K *
Empower innovative drug discovery as a nonclinical safety leader, guiding multidisciplinary teams from target identification to regulatory approval in immunology and oncology, ensuring patient safety...
6 days ago
Principal Scientist (Scientific Director Level)- Nonclinical Drug Safety
$176K - $277K *
Elevate drug discovery by leading the Nonclinical Drug Safety strategy across multiple therapeutic areas, ensuring innovative and effective assessment of drug candidates while collaborating with cross...
6 days ago
Principal Scientist (Scientific Director Level)- Nonclinical Drug Safety
$176K - $277K *
Drive innovation in drug development by leading nonclinical safety strategies across diverse therapeutic areas, collaborating with cross-functional teams to ensure the success of novel medicines from...
6 days ago
Principal Scientist (Associate Director), Reagent Product Development
$175K - $200K *
Join a team that's redefining protein sequencing by leading product development for innovative reagents and workflows. Shape technical strategy, guide cross-functional collaboration, and make a lastin...
2 weeks ago
$110K - $130K *
Contribute to major client projects by driving single-particle cryo-EM processes from sample optimization to structure determination, mentoring junior scientists, and engaging with clients through pre...
4 days ago
Senior Scientist, Cytometric Profiling
$131K - $206K *
Join a team that's advancing Immunology research by profiling therapeutic targets using high-dimensional flow cytometry in a collaborative lab environment, supporting preclinical and clinical program...
4 days ago
Senior Scientist - Cell Culture / Stem Cell
$95K - $100K *
Drive innovative cell culture research, optimize stem cell models, and execute experiments with precision. Collaborate in a fast-paced lab environment while promoting efficiency and detail-oriented pr...
Reposted 3 weeks ago
Principal Scientist/Director (Downstream), Biologics Drug Substance Commercialization (BDSC)
$173K - $272K *
Elevate your career by leading a team of scientists in advancing downstream biologics. Drive strategic initiatives, ensuring regulatory compliance while transforming complex processes across diverse m...
3 days ago
Principal Scientist/Director (Downstream), Biologics Drug Substance Commercialization (BDSC)
$173K - $272K *
Advance your career by leading a team of scientists in downstream processing for late-stage biologics. Drive innovation, influence manufacturing strategies, and mentor talent while ensuring regulatory...
3 days ago
$120K - $140K *
Create a competitive global product portfolio in molecular diagnostics. Lead strategy, drive growth, and ensure compliance while collaborating with cross-functional teams to enhance product offerings...
4 days ago
Senior Proteomics Scientist Group Leader
$90K - $105K *
Contribute to innovative biomarker discovery and mechanism studies using advanced proteomics and analytics. Collaborate with cross-functional teams to enhance therapeutic platforms and improve sample...
2 weeks ago
Senior Associate Scientist/ Principal Research Associate, Antibody and Protein Engineering
$85K - $97K *
Engineer innovative solutions within protein engineering, impacting biotherapeutic lead generation through expression, purification, and characterization of antibodies. Collaborate in a dynamic team t...
3 weeks ago
$100K - $120K *
Transform cutting-edge research initiatives and lead a multidisciplinary team while developing innovative materials and processes. Drive technical programs that support long-term growth in a dynamic...
1 week ago
Principal Market Development Manager - Environmental and Materials Science
$120K - $145K *
Partner with us to drive growth in environmental and materials science across the Americas. Lead strategic initiatives, collaborate with teams, and champion market trends to achieve revenue goals and...
2 weeks ago
Senior ML Scientist, Biological Systems
$268K - $358K *
Pioneer groundbreaking domain models connecting biological data with machine learning, utilizing innovative methodologies to interpret complex biological interactions and guide experimental strategies...
Today
$105K - $129K *
Transform chemical regulatory practices by managing project deliverables, collaborating with teams, and providing regulatory expertise for diverse clientele while ensuring compliance with environmenta...
3 weeks ago
Senior Research Engineer, Research & Early Development
$87K - $162K *
Advance your career by tackling complex engineering challenges in DNA sequencing. In this collaborative research role, you'll design, fabricate, test, and optimize innovative systems that drive techno...
1 week ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.