Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$125K - $150K *

Engage in the design and execution of mouse studies to evaluate therapeutic candidates, employing pharmacokinetics and safety data to guide decision-making on next steps in research and development...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$156K - $214K *

Champion innovative medicinal chemistry strategies by leading multidisciplinary teams. Leverage your expertise in organic synthesis and data analysis to optimize lead compounds, mentor talent, and dri...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$112K - $168K *

Advance your career by driving innovative cell line development and viral packaging, leveraging high-throughput screening and analytics to optimize clone performance, and collaborating with interdisci...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$255K - $402K *

Champion innovative therapies as a Principal Scientist in Translational Medicine. Collaborate to lead early clinical development in neuroscience, advancing novel treatments from concept to clinical tr...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$255K - $402K *

Transform the landscape of neuroscience therapeutics by leading innovative early clinical development strategies, collaborating with diverse teams to address neurologic and psychiatric disorders, and...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Discover innovative solutions in drug discovery and AI research. Collaborate with top scientists, refine products, and tackle complex biological challenges to drive partner success and improve therape...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$176K - $277K *

Grow your career with a leadership role defining nonclinical drug safety strategies. Collaborate across functions to assess risks, promote innovative thinking, and drive decisions that impact therapeu...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $277K *

Deliver innovative drug safety strategies across multiple therapeutic areas, driving cross-functional collaboration from discovery through to regulatory submissions. Lead risk assessments and shape pr...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $277K *

Empower innovative drug discovery as a nonclinical safety leader, guiding multidisciplinary teams from target identification to regulatory approval in immunology and oncology, ensuring patient safety...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $277K *

Elevate drug discovery by leading the Nonclinical Drug Safety strategy across multiple therapeutic areas, ensuring innovative and effective assessment of drug candidates while collaborating with cross...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $277K *

Drive innovation in drug development by leading nonclinical safety strategies across diverse therapeutic areas, collaborating with cross-functional teams to ensure the success of novel medicines from...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $200K *

Join a team that's redefining protein sequencing by leading product development for innovative reagents and workflows. Shape technical strategy, guide cross-functional collaboration, and make a lastin...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Contribute to major client projects by driving single-particle cryo-EM processes from sample optimization to structure determination, mentoring junior scientists, and engaging with clients through pre...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$131K - $206K *

Join a team that's advancing Immunology research by profiling therapeutic targets using high-dimensional flow cytometry in a collaborative lab environment, supporting preclinical and clinical program...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $100K *

Drive innovative cell culture research, optimize stem cell models, and execute experiments with precision. Collaborate in a fast-paced lab environment while promoting efficiency and detail-oriented pr...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Elevate your career by leading a team of scientists in advancing downstream biologics. Drive strategic initiatives, ensuring regulatory compliance while transforming complex processes across diverse m...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Advance your career by leading a team of scientists in downstream processing for late-stage biologics. Drive innovation, influence manufacturing strategies, and mentor talent while ensuring regulatory...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $140K *

Create a competitive global product portfolio in molecular diagnostics. Lead strategy, drive growth, and ensure compliance while collaborating with cross-functional teams to enhance product offerings...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Contribute to innovative biomarker discovery and mechanism studies using advanced proteomics and analytics. Collaborate with cross-functional teams to enhance therapeutic platforms and improve sample...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $97K *

Engineer innovative solutions within protein engineering, impacting biotherapeutic lead generation through expression, purification, and characterization of antibodies. Collaborate in a dynamic team t...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform cutting-edge research initiatives and lead a multidisciplinary team while developing innovative materials and processes. Drive technical programs that support long-term growth in a dynamic...

Kingston, ONIn-Person

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Partner with us to drive growth in environmental and materials science across the Americas. Lead strategic initiatives, collaborate with teams, and champion market trends to achieve revenue goals and...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$268K - $358K *

Pioneer groundbreaking domain models connecting biological data with machine learning, utilizing innovative methodologies to interpret complex biological interactions and guide experimental strategies...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $129K *

Transform chemical regulatory practices by managing project deliverables, collaborating with teams, and providing regulatory expertise for diverse clientele while ensuring compliance with environmenta...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$87K - $162K *

Advance your career by tackling complex engineering challenges in DNA sequencing. In this collaborative research role, you'll design, fabricate, test, and optimize innovative systems that drive techno...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.