Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$95K - $115K *
Transform scientific initiatives as a program leader, coordinating complex, cross-functional projects that advance customer success and drive innovation in the life sciences sector while ensuring time...
5 days ago
$149K - $173K *
Lead the charge in advancing toxicological risk assessment through innovative scientific strategies, collaborating across teams to ensure product safety and regulatory compliance in a globally diverse...
4 days ago
$80K - $95K *
Lead the charge in biological surveys and project support, guiding teams through all project phases while fostering a positive, safety-focused culture and ensuring environmental compliance...
2 weeks ago
Sr./Staff Technical Program Manager - Copper
$110K - $130K *
Lead execution of capital projects, coordinating across teams to ensure delivery on scope, schedule, budget, and risk management. Drive standardization and optimize usage of software tools for enhance...
1 week ago
$110K - $130K *
Join our dynamic Civil engineering team to deliver innovative solutions that adhere to regulatory standards while mentoring the next generation of engineers. Engage in diverse projects, manage resourc...
1 week ago
$80K - $95K *
Manage and optimize customer projects, ensuring timely delivery and high-quality standards. Collaborate with clients, technicians, and cross-functional teams on budgeting, risk management, and complia...
2 weeks ago
Principal Scientist, Synthetic & Discovery Chemistry
$140K - $190K *
Join a dynamic team to lead innovative small molecule synthesis initiatives, optimize automated workflows, and mentor emerging scientists, all while enhancing chemical discovery strategies in a collab...
4 days ago
$100K - $120K *
Transform laboratory operations by managing staff, ensuring compliance, and enhancing workflow efficiency to meet rigorous testing standards and client expectations...
1 week ago
$80K - $95K *
Lead laboratory operations and team performance in environmental testing. Oversee compliance with quality standards and manage analytical activities, ensuring safety and efficiency while driving conti...
1 week ago
Sr. Dir., Strategic Technology Initiatives Lead
$230K - $384K *
Bring your expertise to lead strategic technology initiatives, aligning AI programs with eight Digital Core Platforms. Oversee Senior Technical Architects while ensuring cohesive delivery and governan...
2 days ago
$110K - $130K *
Unlock potential by delivering top-tier mechanical engineering services, leading projects and fostering collaboration within a dynamic team to meet rigorous client and regulatory standards, ensuring t...
Reposted 4 days ago
Principal Software Engineer, AI Agents & Generative AI
$150K - $220K *
Elevate your career by designing and deploying cutting-edge AI software that transforms geospatial data into actionable insights. Drive autonomous decision-making and enhance model reliability in a hi...
2 weeks ago
Director, Manufacturing Engineering
$125K - $150K *
Lead the charge in engineering strategy and capital investment, ensuring compliance, reliability, and growth through effective collaboration and infrastructure planning within a dynamic pharmaceutical...
Yesterday
$100K - $120K *
Lead the charge in managing Linux systems administration and cybersecurity operations, ensuring optimal system performance and security across diverse environments. Drive technical innovation and oper...
Reposted 3 weeks ago
$100K - $120K *
Shape the future of advanced cybersecurity by managing a dynamic lab environment. Oversee system administration, technology deployment, and tactical solutions to support mission-critical operations an...
Reposted 3 weeks ago
$95K - $115K *
Unlock potential by leading lab network infrastructure efforts, enhancing cyber defense capabilities through design, implementation, and maintenance of robust systems while ensuring optimal performanc...
Reposted 3 weeks ago
$94K - $112K *
Champion advanced network solutions by investigating cyber incidents, designing robust infrastructures, and ensuring optimal system performance for critical government operations. Collaborate across t...
3 weeks ago
Protein Expression, Product Specialist III
$70K - $106K *
Champion revenue expansion and market growth in protein expression solutions, leveraging technical expertise and strong sales acumen. Collaborate with cross-functional teams to deliver tailored custom...
2 weeks ago
Staff Research Engineer/Scientist
$202K - $354K *
Transform enterprise agent learning by leading research projects that enhance capabilities in planning, reasoning, and tool use. Drive innovation through hypothesis-driven experimentation and collabor...
1 week ago
Sr. Research Associate, Clinical Biomarker Laboratory, Flow Cytometry
$74K - $118K *
Accelerate your career by applying your expertise in flow cytometry to deliver key clinical data. Join our team to develop and validate assays, execute sample testing, and produce high-quality results...
Reposted 1 week ago
Senior AI Transformation Process Analyst
$175K - $190K *
Empower business transformation by identifying AI opportunities, analyzing processes, and developing blueprints for agentic workflows. Collaborate with stakeholders to drive impactful recommendations...
2 weeks ago
Director/Head, Pharmacovigilance
$200K - $245K *
Lead the pharmacovigilance function, guiding a dedicated team in operational oversight, ensuring compliance with regulations, and managing risk assessments for drug safety, all while contributing to t...
1 week ago
Principal Engineer, Core Infrastructure
$114K - $234K *
Join a team that's shaping the future of cloud infrastructure by designing, building, and optimizing self-healing, scalable distributed systems that can adapt and thrive in a demanding operational env...
Yesterday
Principal Engineer, Core Infrastructure
$114K - $234K *
Champion innovation by designing and implementing advanced scalable systems that enhance cloud infrastructure reliability, efficiency, and performance. Lead complex projects, mentoring teams, and driv...
Yesterday
Principal Engineer, Core Infrastructure
$114K - $234K *
Join a team that's revolutionizing cloud infrastructure by designing resilient systems that scale autonomously. Shape next-gen technologies and optimize platform components for high availability and p...
4 days ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.