Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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Compensation
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$132K - $175K *

Lead the charge in geochemistry innovation, driving impactful projects from mine design to closure. Collaborate with multidisciplinary teams, provide thought leadership, and mentor emerging profession...

4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$132K - $175K *

Elevate your geoscience expertise by leading innovative projects in mining geochemistry. Collaborate with multidisciplinary teams, drive environmental assessments, and mentor the next generation while...

Whitehorse, YTIn-Person

4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$132K - $175K *

Transform complex geochemical data into actionable strategies while leading multidisciplinary teams in mining projects. Drive innovation in environmental assessments from mine design to closure, mento...

Calgary, ABIn-Person

4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$132K - $175K *

Lead transformative geochemistry projects, shaping sustainable mining practices. Guide teams through complex environmental assessments and deliver innovative solutions while mentoring the next generat...

Vancouver, BCIn-Person

4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$114K - $234K *

Lead the charge in developing scalable, elastic distributed systems, optimizing components for high-throughput workloads while ensuring reliability, fault-tolerance, and security in complex architectu...

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$214K - $358K *

Innovate and lead the engineering delivery of AI systems for Medical Affairs. Collaborate with cross-functional teams to ensure production reliability and engineering excellence while guiding a talent...

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$214K - $358K *

Create and lead a high-performance engineering team to build enterprise-scale AI systems in Medical Affairs. Collaborate cross-functionally to ensure high-quality delivery and production reliability...

6 days ago

  •   11 - 15 years exp.  •   Healthcare

$114K - $234K *

Lead the design and development of scalable, fault-tolerant distributed systems, optimizing high-throughput workloads while ensuring performance, reliability, and security. Mentor peers and proactivel...

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Elevate your career by providing on-site technical expertise in packaging materials for military operational rations. Collaborate with an innovative team to develop sustainable solutions that enhance...

3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$105K - $145K *

Join a team that's committed to advancing geology practices by leading site evaluations, developing accurate resource models, and coaching talent to optimize mining operations. Your expertise will sha...

4 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$109K - $174K *

Elevate your impact as a process engineering SME, driving innovation and compliance in Drug Substance technologies within a global manufacturing network while collaborating with cross-functional teams...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$189K - $216K *

Champion the advancement of chemical engineering for drug substance production. Lead and optimize manufacturing processes and oversee external sites, ensuring compliance and excellence from late-stage...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $225K *

Champion innovative bioprocessing solutions by leading a global hardware engineering team, driving strategy, and ensuring product excellence. Collaborate cross-functionally to enhance product developm...

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$190K - $225K *

Lead and cultivate a high-performing hardware engineering team, driving innovative bioprocessing instrumentation development while ensuring alignment with business goals, quality standards, and regula...

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$69K - $110K *

Accelerate product innovation by leveraging your analytical expertise in a cross-functional team. Collaborate to optimize processes, ensure compliance, and enhance product quality through hands-on tes...

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $180K *

Unlock potential by leading biological compliance for infrastructure projects, ensuring successful navigation of CEQA, multi-agency permitting, and construction oversight across California and the wes...

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Contribute to innovative biotechnology projects as a key scientist in fermentation processes, collaborating with multi-disciplinary teams to optimize strain evaluations and bioprocess development whil...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$96K - $120K *

Lead and execute quality control testing in a GMP environment, collaborating with teams to ensure compliance and continuous improvement while guiding junior staff in methodologies and practices to ele...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $115K *

Lead the Quality Control Department to ensure products exceed customer specifications by overseeing inspections, maintaining quality systems, and fostering strong supplier and customer relations. Driv...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$137K - $189K *

Champion product development projects from concept to launch by leading cross-functional teams, ensuring alignment with strategic goals and managing resources effectively to deliver high-quality outco...

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Solve complex formulation challenges for biologics by leading R&D initiatives, collaborating with external partners, and ensuring compliance in delivering high-quality therapeutics for patient use glo...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$129K - $169K *

Lead the charge in developing innovative medical device products by merging engineering expertise across multiple disciplines. Drive projects from conception to regulatory approval, guiding teams to e...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$137K - $189K *

Join a team that leads product development from concept to launch, managing cross-functional collaboration and driving project success through strategic planning and execution to meet business objecti...

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock potential by leading production operations, ensuring quality, safety, and compliance. Direct a team in a dynamic manufacturing setting while optimizing resources and participating in continuous...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$127K - $152K *

Unlock potential by developing impactful policy content that shapes public health initiatives and drives scientific rigor. Collaborate across diverse teams to enhance access to quality medicines while...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.