Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$105K - $145K *

Lead the charge in advancing mRNA therapeutic processes through innovative design, execution, and optimization of experiments, while collaborating with cross-functional teams to achieve production goa...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Innovate enzyme-based processes to convert agricultural feedstocks into high-value products, collaborating across interdisciplinary teams to advance protein chemistry and enzymology initiatives in a d...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Drive innovative memory systems by fine-tuning models, implementing research algorithms, and collaborating with engineering teams to ensure top-tier performance and reliability, transforming customer...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$79K - $96K *

Transform laboratory research as an Associate Scientist, focusing on mammalian cell culture techniques. This dynamic role allows you to optimize workflows, analyze data, and collaborate with scientist...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive innovative biologics purification processes, collaborating with teams to enhance drug discovery and deliver high-quality therapeutic candidates for transformative patient care...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Pioneer regulatory excellence by leading a dedicated team to ensure compliance and drive innovative product strategies. Collaborate across functions to enhance processes, safeguard quality, and influe...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$228K - $309K *

Elevate customer experience by driving advancements in Conversational AI and NLP. Collaborate with leading experts to develop innovative algorithms and modeling techniques that connect millions with c...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in developing embedded software that integrates seamlessly across complex electromechanical systems, applying systems thinking to drive innovative solutions within scientific instrumen...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$150K - $180K *

Shape the future of deepwater production by optimizing reservoir models and well placement. Engage with multidisciplinary teams to enhance asset recovery while mentoring junior geoscientists and suppo...

2 weeks ago

  •   11 - 15 years exp.  •   Energy & Utilities

$110K - $130K *

Unlock potential by joining a global team focused on clinical research compliance. You will negotiate and interpret informed consent for biospecimens, shaping the future of precision medicine and ensu...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Lead the charge in managing aerospace programs by ensuring precise cleaning and contamination control processes meet stringent standards while aligning operations with customer requirements for timely...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$89K - $123K *

Advance the future of large molecule bioanalysis by developing and applying cutting-edge LC-MS/MS and LC-HRMS methods for the preclinical evaluation of complex biologics and their interactions in biol...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$93K - $110K *

Engage in groundbreaking antibody discovery and optimization, managing multiple projects to deliver high-quality data. Collaborate across teams to foster innovation and maintain rigorous scientific st...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$121K - $166K *

Collaborate with a dynamic team to design and develop cutting-edge mechanical solutions for state-of-the-art Life Science instruments, guiding projects from conception to production, while enhancing p...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$121K - $166K *

Elevate the future of medical diagnostics by developing innovative mechanical systems for next-generation Life Science instruments, collaborating within a dynamic R&D team from concept through product...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion preclinical research as a molecular biology expert, leading a team to innovate and implement assays that support product development and IND enabling studies, while collaborating across funct...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by synthesizing and characterizing innovative materials in a collaborative environment. Contribute to groundbreaking energy storage technology through hands-on experimental chemistry...

3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$92K - $110K *

Join us to lead engineering initiatives and enhance manufacturing processes, ensuring product quality and operational excellence through innovative solutions and collaboration across teams to drive co...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$81K - $112K *

Drive operational excellence in QC Analytical Lab by leading testing activities, ensuring compliance with regulations, mentoring staff, and managing resources to support product releases and process v...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Make your mark at the forefront of environmental science; lead diverse projects, manage teams, and ensure quality deliverables while advancing your expertise across multiple geographies and markets...

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$190K - $210K *

Shape the future of bioprocess technology by leading interdisciplinary efforts that enhance product performance and industry standards while driving innovation in bioreactor solutions for protein ther...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $210K *

Innovate in bioprocessing as a subject matter expert for single-use bioreactors, leading interdisciplinary collaboration while shaping product standards and engaging with customers to drive industry a...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$246K - $267K *

Transform oncology laboratory operations by leading a team focused on quality, efficiency, and compliance. Oversee financials, implement process improvements, and ensure adherence to regulatory standa...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$165K - $175K *

Advance mission integration through innovative systems engineering and architecture design, ensuring robust capability delivery for diverse operational needs in a dynamic defense environment...

3 weeks ago

  •   15+ years exp.  •   Aerospace & Defense

$95K - $115K *

Grow your career with a dynamic team focused on advanced analytical development. You'll drive innovative LC-MS techniques for biotherapeutics, collaborating across functions to enhance drug developmen...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.