Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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$170K - $200K *

Help us lead end-to-end product development, driving cross-functional teams to ensure timely delivery, technical rigor, and strategic program management through all phases from concept to production i...

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$135K - $185K *

Lead the charge in enhancing laboratory operations by supervising teams and driving process improvements for optimal efficiency. Collaborate with clients and stakeholders to ensure compliance and prod...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$172K - $202K *

Lead the charge in AD&QC activities for late-stage oligonucleotide programs, ensuring regulatory submissions, compliance, and collaboration across teams to drive successful manufacturing and product q...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $185K *

Innovate project planning through expert development and management of schedules, ensuring timely and accurate execution across all project phases. Collaborate with diverse teams to drive initiatives...

Mississauga, ONIn-Person

3 weeks ago

  •   11 - 15 years exp.  •   Energy & Utilities

$175K - $185K *

Lead the planning and management of large-scale projects by developing and maintaining accurate project schedules, collaborating with cross-functional teams, and ensuring high-quality deliverables to...

Vancouver, BCIn-Person

3 weeks ago

  •   11 - 15 years exp.  •   Energy & Utilities

$192K - $357K *

Innovate solutions by engineering scalable ML systems and autonomous agents for drug discovery. Collaborate with scientists to translate complex challenges into efficient products while guiding techni...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$192K - $357K *

Drive scalable ML engineering in drug discovery, leading the development of cutting-edge agentic systems and foundation models, optimizing MLOps while collaborating with scientists to create efficient...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$74K - $85K *

Join a team that's leading mechanical testing excellence! Oversee a dedicated crew in executing rigorous pneumatic and leak detection testing, while ensuring safety and quality in operations. Drive in...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$117K - $201K *

Unlock potential by driving innovation in data science and AI within Immunology. Collaborate with diverse teams to design impactful strategies and solutions that enhance research outcomes and improve...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $201K *

Make your mark as a Principal Scientist, guiding data science and AI initiatives in Immunology. Collaborate with cross-functional teams to innovate and implement data-driven solutions that enhance res...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $201K *

Lead the charge in developing innovative data science strategies for Immunology, collaborating with cross-functional teams to enhance research outcomes and implement AI-enabled solutions for better he...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $201K *

Drive innovation in immunology R&D through data science and AI, leveraging cutting-edge technology to enhance research execution and decision-making across cross-functional teams in a collaborative, i...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $201K *

Join a team that's transforming immunology R&D through innovative data science and AI. Collaborate across functions to design impactful solutions that improve research outcomes and decision-making in...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead development of ssNMR techniques for pharmaceutical material characterization. Drive experimental design, data interpretation, and collaboration with Materials Science colleagues to advance scient...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Explore the intersection of data science and manufacturing. Leverage AI, machine learning, and statistical analysis to optimize wafer fabrication processes and drive continuous improvement across dive...

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$138K - $165K *

Accelerate data-driven insights by analyzing wafer fabrication datasets using AI, ML, and statistical techniques. Collaborate cross-functionally to enhance process understanding, monitor production an...

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$115K - $156K *

Advance the future of biotechnology by leading engineering efforts in process development, scale-up, and technology transfer, while ensuring safety, compliance, and operational excellence in synthetic...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $156K *

Join a team that's advancing chemical engineering by leading technical evaluations, optimizing processes, and ensuring the smooth transfer of novel technologies, while collaborating across multifuncti...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Lead and mentor the engineering team while optimizing optical thin film manufacturing processes. Ensure compliance, drive continuous improvement, and support cross-functional collaboration to enhance...

4 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$187K - $257K *

Elevate your career by serving as a scientific peer in clinical settings. Interact with KOLs, communicate complex data, and support research initiatives to enhance patient care and inform strategy wit...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$187K - $257K *

Innovate impactful collaborations as a Medical Science Specialist driving scientific communication, supporting research initiatives, and translating complex clinical data for key stakeholders to advan...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$111K - $125K *

Transform product development processes by leading cross-functional teams, managing timelines, budgets, and regulatory requirements for new consumables. Drive stage-gate execution and enhance project...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$111K - $125K *

Transform your career by leading cross-functional teams to deliver innovative NPD and value engineering programs. Drive execution excellence, manage risks, and align stakeholder priorities in a dynami...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Take ownership of project lifecycle management, ensuring successful execution and delivery. Collaborate with global teams, communicate with stakeholders, and align project timelines to drive innovativ...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$115K - $192K *

Lead the charge in building innovative AI solutions, guiding from concept through production while establishing robust architectures and mentoring your team in a collaborative environment. Drive impac...

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.