Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$90K - $130K *

Join a team that's at the forefront of groundbreaking technologies, providing analytical and programmatic support to enhance national security initiatives while collaborating with the Department of De...

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$150K - $160K *

Discover a dynamic role driving enterprise API strategy, architecture, and governance. Collaborate across teams to implement scalable solutions that enhance integration and innovation for digital tran...

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$117K - $176K *

Join a dynamic team to drive microbiological testing initiatives, ensuring compliance with regulatory standards while supporting robust radiopharmaceutical manufacturing processes in a hands-on labora...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$141K - $176K *

Drive production excellence by leading strategy and operations for upstream/downstream manufacturing. Collaborate across teams to enhance quality, safety, and efficiency while managing performance goa...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $117K *

Grow your career with hands-on process development in a dynamic lab environment. Collaborate on microbial processes, engage in technology transfer, and contribute to impactful projects while ensuring...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Drive innovative engineering solutions in multidisciplinary teams, overseeing design, analysis, and project delivery. Ensure technical excellence while mentoring engineers in hazardous environments. F...

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$150K - $180K *

Pioneer cutting-edge CMC strategies in drug development, leading teams from early-stage evaluations through to regulatory submissions, ensuring compliance and driving excellence across all phases of p...

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$262K - $393K *

Engage in defining and leading an innovative preclinical pharmacology strategy while integrating cutting-edge technologies that drive therapeutic advancements and optimize data-driven decision-making...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$115K - $184K *

Join a team that's empowering global HSE initiatives, enhancing compliance, and driving sustainability through expert project management, IT solutions, and emergency management. Lead and innovate with...

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $120K *

Lead the charge in creating a comprehensive global product roadmap for environmental monitoring solutions. Drive cross-functional collaboration and optimize product portfolios while ensuring alignment...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$120K - $160K *

Unlock potential by leading mechanical hardware design for innovative fusion devices. Mentor a dynamic engineering team while driving technical standards, collaboration, and process improvements to en...

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$284K - $400K *

Drive DMPK strategy and innovation to transition programs to clinical development, leveraging data-driven models and cross-functional collaboration to enhance drug discovery processes...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$284K - $400K *

Champion innovative drug development by leading DMPK strategy, overseeing projects from hit-identification to IND-enabling studies, and collaborating across teams to enhance predictive modeling and hu...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$75K - $90K *

Help us drive innovation by developing custom products with deep customer insights, collaborating across teams, and solving complex scientific challenges to enhance research and applications...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$139K - $231K *

Collaborate with scientific teams to enhance Oncology R&D through data pipelines and AI solutions. Innovate analytical models and machine learning techniques to improve healthcare workflows and decisi...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$204K - $218K *

Reimagine the future of material science by leading metrology for crystalline films. Drive improvements in growth processes and device performance through advanced analysis and collaboration with engi...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $95K *

Tackle complex chemical studies and drive innovative product development while independently conducting analytical tests. Collaborate with cross-functional teams to support operations, mentor colleagu...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $100K *

Champion process efficiency and safety in drug product manufacturing by monitoring and improving production processes, validating changes, and ensuring compliance for clinical and commercial products...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Drive progress at the forefront of global regulatory science, leading a team of experts in human and environmental safety. Collaborate with diverse disciplines to shape regulatory strategies and ensur...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$177K - $329K *

Shape the future of Generative AI infrastructure, developing scalable multi-agent systems and ensuring robust governance. Collaborate globally to deliver innovative AI solutions enhancing healthcare o...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$147K - $245K *

Drive program success as a Sr Program Manager overseeing complex product development projects and cross-functional initiatives. Lead a motivated team while establishing objectives, managing resources...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$74K - $118K *

Join a team that's driving innovation in cell-based and molecular assays. Collaborate across functions to generate quality data and advance technologies within genome sciences, enhancing the developme...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$121K - $171K *

Execute advanced tissue manufacturing projects, leading from concept to production ramp-up. Serve as a technical authority and mentor while collaborating cross-functionally to innovate and optimize pr...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Champion quality leadership in laboratory operations, ensuring compliance and continuous improvement. Leverage strategic partnerships to drive process enhancement, team development, and operational ex...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$72K - $96K *

Play a key role in optimizing manufacturing processes by driving significant projects and improvements. Work collaboratively within a team to enhance quality, reliability, and performance through engi...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.