Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$142K - $193K *

Develop advanced computer vision and machine learning models to enhance visual media experiences. Lead innovative solutions integrating AI, transforming customer interactions and driving personalizati...

1 week ago

  •   5 - 7 years exp.  •   Media

$100K - $120K *

Drive assay development and validation in a high-complexity laboratory. Collaborate cross-functionally to enhance clinical research operations, ensure compliance, and optimize workflows with cutting-e...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$148K - $297K *

Lead the charge in advanced AI initiatives, bridging technology and engineering solutions to develop scalable ML infrastructure and maintain robust AI platforms, while ensuring compliance and collabor...

Reposted yesterday

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Empower growth by leading talent acquisition strategies, mentoring teams, and optimizing processes in a dynamic biotech environment. Drive recruitment for critical roles in manufacturing operations to...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $180K *

Join a team that's shaping the future of data analytics. As a Staff Data Scientist, you'll drive impactful projects that enhance decision-making through statistical methods, predictive modeling, and c...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $180K *

Transform data into powerful insights! Drive impactful analytical projects, collaborate across teams, and implement advanced statistical methods to enhance decision-making and business results. Shape...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $130K *

Innovate with us as you drive AI advancements through data integration, model development, and performance improvement on cutting-edge cloud platforms while ensuring ethical and high-quality outcomes...

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $115K *

Empower your career by leading supplier quality initiatives in materials engineering. Collaborate with cross-functional teams to enhance supplier performance and drive quality assurance efforts for cr...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $130K *

Shape the future of geotechnical consulting through innovative investigation techniques. Lead complex projects, ensuring quality and safety while mentoring junior staff. Collaborate on environmental a...

2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$130K - $160K *

Champion the QC Analytical team by driving method performance and regulatory compliance while collaborating across functions for impactful program development and quality assurance...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead the charge in mechanical engineering excellence, overseeing team dynamics and delivering innovative designs for energy and industrial projects, ensuring compliance and quality from concept to exe...

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$117K - $184K *

Unlock potential by developing innovative biomanufacturing technologies and processes. Collaborate with cross-functional teams to support the production of life-changing medicines while mentoring juni...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$112K - $169K *

Advance your career in bioinformatics by designing and optimizing siRNA sequences while collaborating with cross-functional teams in the Oligonucleotide Therapeutics Group, targeting innovative gene s...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$154K - $231K *

Lead the development of machine learning models and algorithms for next-generation sequencing applications, collaborating cross-functionally to translate genomic data into actionable insights and prod...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Innovate solutions by evaluating production processes, implementing design improvements, and managing mechanical documentation to enhance utility infrastructure and ensure compliance with regulatory s...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Lead innovative clinical pharmacology strategies to enhance early-phase programs, collaborating with cross-functional teams to interpret data, design studies, and apply advanced analytics, driving sci...

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $144K *

Shape the future of enterprise sales in physical sciences by engaging top clients. Leverage your technical acumen to drive sales of cutting-edge AI and autonomous lab solutions, while building strateg...

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$136K - $223K *

The Applied Scientist II role at Prime Video involves developing machine learning models for recommendation and search systems, collaborating with scientists and engineers to enhance product insights...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$235K - $248K *

Drive the production of clinical datasets and reporting outputs by leading programming teams, ensuring compliance with regulatory standards, and collaborating across departments to deliver high-qualit...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$171K - $222K *

Transform Prime Video by developing AI solutions as a hands-on machine learning expert. Collaborate with engineers to design, implement, and evaluate state-of-the-art models, enhancing service for mil...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$105K - $153K *

Shape your career by leading high-impact bacteriology research and guiding high-containment studies. Spearhead method developments and support countermeasure strategies with a dynamic research team. Y...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Elevate your career by joining our R&D team innovating regenerative medicine through the design of advanced cell- and tissue-based products. Collaborate with scientists to develop assays, generate pro...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $130K *

Join a team that's dedicated to advancing drug development through innovative pharmacometric analyses, collaborating with experts to drive decision-making across clinical projects and enhance drug eff...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Elevate laboratory operations by executing work plans and maintaining compliance with regulations. Collaborate on method development, documentation, and efficiency projects to enhance analytical proce...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$102K - $133K *

Transform the metallization landscape by optimizing plating processes for textile materials. Collaborate cross-functionally, develop innovative solutions, and advance from lab experiments to productio...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.