Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$98K - $206K *

Design and lead innovative algorithms for space-based remote sensing, translating advanced signal processing concepts into effective software applications. Collaborate cross-functionally while mentori...

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$103K - $217K *

Join a pioneering team focused on advanced signal processing and software application development for space-based remote sensing technologies, protecting national security with innovative radar soluti...

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $140K *

Develop innovative NGS assays by leveraging lab techniques and data analysis, while supporting existing products. Collaborate across teams to communicate findings and drive product success in a dynami...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a team that drives clinical safety and compliance by leading Pharmacovigilance initiatives. Oversee safety signal processes, author critical safety reports, and mentor staff to ensure the integri...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive your career forward as you manage critical Pharmacovigilance activities, ensuring safety compliance and signal management for clinical trials and products. Collaborate with teams to analyze data...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$183K - $194K *

Pioneer innovative discoveries in computational biology, integrating diverse data modalities to identify therapeutic targets and champions of drug development. Collaborate with top-tier scientists to...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Optimize platform engineering strategies by leading a cross-functional team to enhance architecture, analytics, and operational efficiency while driving innovation in self-service capabilities and AI...

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Lead validation initiatives for sterile manufacturing systems, ensuring compliance and efficiency. Collaborate with cross-functional teams to enhance operations and mentor peers. Drive continuous impr...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$195K - $293K *

Shape the future of cutting-edge DNA sequencing instruments by overseeing electrical system architecture and providing hands-on design and troubleshooting expertise, collaborating across multidiscipli...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$117K - $201K *

Drive innovation and improve surgical outcomes as a Principal Scientist overseeing preclinical research. Lead cross-functional teams in developing non-clinical evidence for regulatory approvals and su...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$117K - $201K *

Unlock potential by leading preclinical research strategies, ensuring product safety and efficacy while collaborating with cross-functional teams to meet project goals, deliver innovative surgical tec...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$310K - $420K *

Shape the future of generative evaluation at an innovative tech firm. Drive research and establish evaluation frameworks that connect design quality to user experience across global teams, influencing...

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$140K - $210K *

Advance your career by driving impactful data solutions in the Life Sciences sector. Collaborate with pharmaceutical partners to enhance research and commercial outcomes through innovative strategies...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $210K *

Unlock opportunities in precision medicine by driving partnerships with pharmaceutical companies. Cultivate relationships and develop tailored solutions to support clients' research and commercial obj...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $210K *

Dive into the forefront of precision medicine, driving transformative partnerships with pharmaceutical companies to enhance research and outcomes through innovative data solutions and insights, while...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $95K *

Elevate environmental consulting through scientific expertise and analysis. Collaborate with diverse teams on mine closure and hydrologic investigations, applying data to create sustainable solutions...

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $130K *

Manage quality control and analytical development for microbial products, ensuring compliance with specifications and leading assay validation. Collaborate cross-functionally to enhance product qualit...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Shape the future of diagnostics by leading advanced lab investigations and methodologies. Mentor peers, ensure quality compliance, and drive improvements to deliver reliable results in a collaborative...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Analyze metabolic pathways for drug candidates using advanced mass spectrometry techniques. Collaborate with pharmacology and toxicology teams to develop innovative methodologies and establish in vitr...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Contribute to the development of enzymatic profiling and clearance prediction for drug candidates through rigorous laboratory studies, collaborating across disciplines to enhance metabolite understand...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Pioneer the future of clinical project management by leading teams, guiding projects, and enforcing quality standards. Collaborate effectively with various departments to meet client specifications an...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $225K *

Join a team that's pioneering high-power RF systems integration for fusion energy. You'll design and optimize advanced electronics in a collaborative environment, transforming the future of energy tec...

3 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$120K - $145K *

Drive advanced AI solutions by designing, optimizing, and integrating cutting-edge algorithms into product features, ensuring high quality and efficient performance for a transformative biotech applic...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$81K - $107K *

Unlock potential by designing and optimizing lipid nanoparticle formulations to enhance nucleic acid therapeutics. Collaborate across teams to advance innovative delivery vehicles while maintaining ri...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$81K - $107K *

Join a team that's advancing lipid nanoparticle formulations for nucleic acid therapeutics, where you'll design, produce, and optimize processes in a collaborative, fast-paced environment while contri...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.