Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$140K - $170K *

Champion innovative pharmacology studies to drive anti-infective drug development. Leverage expertise in both in vitro and in vivo models to guide project strategy, collaborating across teams and ensu...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$138K - $190K *

Optimize cancer diagnostics by developing innovative automated assays in a cross-functional team, enhancing molecular biology workflows, and leading studies for early cancer detection...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $150K *

Elevate product innovation by leading cross-functional teams to develop and execute a multiyear roadmap of over-the-counter and cosmetic topical products that meet consumer needs and business objectiv...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's dedicated to ensuring quality assurance in national security lab programs. Leverage your analytical chemistry expertise to support audit preparation, proficiency testing, and compli...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$115K - $144K *

Champion the transition of IVD Next-Generation Sequencing assays from R&D to Operations while ensuring compliance with quality standards, collaborating across functions to drive project completion in...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Optimize analytical methods and provide robust support for drug substance testing, independently organizing work, evaluating data, and ensuring compliance with regulatory standards while engaging with...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of drug discovery by leveraging your preclinical expertise to develop innovative software solutions. Collaborate with engineers and domain experts to enhance scientific workflows and...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$170K - $212K *

Join a dynamic team of biophysicists to accelerate drug discovery through innovative biophysical methods, enhancing target validation, and mechanistic insights for oncology projects while collaboratin...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $100K *

Elevate your career as a Sr. Scientist in Quality Control, applying your expertise in lab sciences and compliance to drive methodologies, testing and continuous improvements in a dynamic laboratory en...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Pioneer innovative approaches in materials diagnostics and interactions, leading R&D efforts for extreme environments. Collaborate with experts to develop and implement strategies that enhance materia...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Empower your career by leading engineering and validation projects in GMP-regulated environments, ensuring operational readiness and compliance while coordinating cross-functional teams for successful...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$157K - $213K *

Transform bioconjugate manufacturing by leading innovative processes and multidisciplinary teams. Drive scientific excellence and mentor future leaders in the pursuit of sustainable and effective drug...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Unlock potential by leading global regulatory strategies in cardiovascular and metabolic programs. Collaborate with cross-functional teams to ensure timely drug approvals while managing complex projec...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Redefine global regulatory strategy by leading complex cardiovascular programs, driving optimal results with minimal oversight while engaging with global regulatory agencies for timely approvals and c...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Lead the charge in global regulatory strategy development for innovative cardiovascular programs, ensuring efficient approval processes and strategic oversight to accelerate drug advancements through...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Unlock your potential as a strategic leader in global regulatory affairs, driving innovative cardiovascular solutions and ensuring rapid approval processes while managing complex development programs...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $180K *

Join a dynamic team as a leader driving innovation in polymer formulation for medical devices. You'll oversee projects from concept to manufacturing, ensuring regulatory compliance while mentoring tal...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$83K - $100K *

Join a dynamic team dedicated to protein purification, employing advanced techniques and equipment in a collaborative laboratory environment. Contribute as a technical expert while ensuring high-quali...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $220K *

Collaborate with cross-functional teams to develop and deploy LLM-driven agents that enhance scientific workflows, ensuring efficient decision-making in drug discovery processes...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive groundbreaking research initiatives to enhance enterprise agentic AI, focusing on tacit knowledge accumulation, continuous learning, resilience, safety, and data privacy within real operational...

Montreal, QCIn-Person

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$177K - $308K *

Drive scientific leadership at the nexus of quantum chemistry, ML, and HTE. Direct initiatives that bridge predictions and experimental outcomes, fostering innovation in reaction discovery through tea...

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$147K - $184K *

Lead biologics formulation and downstream process development, driving innovation and strategy in a collaborative, fast-paced environment. Engage with cross-functional teams and mentor junior staff wh...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Tackle the transformation of innovative compounds into scalable solutions. Drive experimental design and optimization, ensuring consistent results in manufacturing processes. Collaborate across teams...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$250K - $300K *

Shape the future of scientific innovation by leading operational strategies that bridge AI and physical sciences. Drive cross-functional coordination, enhance research visibility, and partner with lea...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$169K - $206K *

Join a team that's advancing innovative cancer therapies. Lead the development of transformative small molecule processes while collaborating cross-functionally, shaping drug development strategies, a...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.