Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$113K - $226K *

Optimize customer relationships and educational programs in Cardiac Rhythm Management and Electrophysiology. Collaborate with teams to enhance product adoption and training initiatives, ensuring high...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $190K *

Pioneer innovative AI solutions to transform biomedical discovery, collaborating with top scientists and engineers to bridge virtual and real-world data, enhancing drug discovery and clinical care pro...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $155K *

Develop and lead comprehensive benefits and compensation programs, ensuring alignment with business goals and enhancing employee experience through strategic management and continuous improvement init...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$177K - $338K *

Help us advance women's health through innovative clinical trial strategies, where you will conduct, support, and report on global studies for cutting-edge compounds, ensuring adherence to regulatory...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $264K *

Pioneer cross-functional collaboration to manage IS projects, ensuring successful implementation and support of applications, upgrades, and integrations while overseeing budgets and resources across S...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $157K *

Advance market share and sales objectives by building strong relationships and leveraging clinical expertise. Collaborate with teams to analyze trends and drive strategic initiatives in a dynamic heal...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$67K - $199K *

Empower operational excellence by leading provider data governance and attribution processes. Collaborate across departments to ensure data integrity, enhance reporting accuracy, and drive continuous...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Accelerate commercial success by engaging healthcare providers and driving product adoption. Collaborate with cross-functional teams to optimize patient access and support innovative therapies in a dy...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$122K - $203K *

Empower teams by leading data governance initiatives, enhancing data quality, and fostering collaboration across business domains. Drive operational excellence and ensure compliance while developing a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Join a dynamic team to drive commercial performance and enhance patient access through strong relationships with healthcare providers, executing strategic business plans in a pivotal role focused on i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Drive impactful oncology solutions by building relationships with key stakeholders. Leverage your expertise to promote innovative products, exceed performance goals, and enhance patient access while n...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$193K - $262K *

Champion the sales force's success by leading a dynamic team focused on optimizing field effectiveness and operational efficiency, driving excellence in performance and insights...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Champion the promotion of oncology products, building strong relationships with key stakeholders. Drive performance goals, manage territory effectively, and ensure patient access to treatments while e...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Make your mark at a leading healthcare organization, delivering high-quality, person-centered care in skilled nursing facilities. Collaborate with teams to improve health outcomes while enjoying auton...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$208K - $250K *

Elevate patient care by providing compassionate, evidence-based services in skilled nursing facilities. Collaborate with teams to improve health outcomes while enjoying autonomy, leadership opportunit...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $250K *

Empower the future of senior care by delivering high-quality, person-centered healthcare in skilled nursing facilities. Build strong relationships, mentor teams, and drive improvements in patient outc...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$54K - $155K *

Lead the charge in telephonic case management, collaborating with patients and care teams to support quality healthcare delivery. Use clinical expertise to assess needs, implement strategies, and ensu...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Advance healthcare solutions by driving sales of innovative diagnostic instruments. Engage with key stakeholders to promote QIAstat-Dx systems, ensuring successful adoption and customer satisfaction t...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead the charge in overseeing compliance frameworks and regulatory trends, ensuring the certification team adapts to changes. Collaborate cross-functionally to integrate policy expertise and support c...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Empower global health initiatives by enhancing supply chain systems across multiple countries. Collaborate with teams to ensure compliance, efficiency, and capacity building in logistics and procureme...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Accelerate progress at the forefront of clinical research by ensuring effective oversight and management of clinical studies. Collaborate with teams to uphold quality standards and drive successful st...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Staffing

$110K - $125K *

Elevate the paper manufacturing sector by driving sales and fostering relationships with key accounts. Leverage your expertise to identify and implement effective chemical applications that enhance ef...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $170K *

Lead the charge in building community connections for Becker Muscular Dystrophy. Engage patients, families, and advocacy groups to enhance awareness and access to resources, while collaborating with i...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Engage with key stakeholders to promote oncology products, build relationships, and drive brand value. Utilize market insights to develop strategic plans, ensuring patient access and exceeding perform...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$174K - $217K *

Drive strategic leadership in industry partnerships and payor strategy, enhancing market access and competitive positioning. Lead a high-performing team to execute a multiyear plan that fosters sustai...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.