Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$100K - $120K *

Lead the execution of innovative topicals projects, ensuring timely delivery and quality. Collaborate across teams to streamline processes and enhance product development, driving growth in a fast-pac...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$90K - $110K *

Elevate senior care by delivering high-quality, relationship-based primary care. Enjoy autonomy and flexibility while collaborating with a dedicated team to improve patient outcomes and enhance the li...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform endpoint management by designing and deploying solutions across a vast device estate. Collaborate with cross-functional teams to ensure security, compliance, and reliability while leveraging...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $150K *

Join a team that's dedicated to transforming addiction treatment through telehealth. Collaborate with physicians to provide comprehensive care for patients with substance use disorders, ensuring a sup...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$120K - $160K *

Champion healthcare innovation by driving product adoption and relationships within key accounts. This role fosters collaboration across teams and builds trust with stakeholders to influence market be...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead the strategic design and management of comprehensive benefits programs, ensuring alignment with employee needs and company objectives. Drive innovation and compliance while enhancing employee eng...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Partner with us to drive transformative healthcare solutions by managing key accounts, fostering relationships, and ensuring measurable outcomes. Your expertise will enhance provider partnerships and...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$189K - $256K *

Join a global team to shape regulatory strategies in biotechnology, supporting product development and lifecycle management in Inflammation and Rare Diseases. Lead regulatory efforts, ensure complianc...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$235K - $329K *

Lead clinical pharmacology initiatives, overseeing drug development across infectious disease and oncology programs. Collaborate with cross-functional teams to drive strategic advancements and ensure...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Grow your career by driving sales and expanding market presence in the Encaps & Inclusions sector. Collaborate with cross-functional teams to deliver innovative solutions while managing key accounts a...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$96K - $118K *

Join a dynamic team to lead pricing and underwriting functions, driving financial analysis and risk evaluation. Collaborate with supervisors and analysts to enhance pricing strategies and support clie...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$297K - $367K *

Grow your career with a pivotal role driving hospital data integration and compliance. Lead execution of clinical data operations, build relationships, and ensure secure data handling while shaping a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $162K *

Join us to develop and implement strategic sales plans, build customer relationships, and achieve sales goals while adhering to ethical practices. Make a positive impact in the pharmaceutical industry...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive client success by leading strategic account teams, ensuring satisfaction, and fostering strong relationships. Leverage expertise to enhance service delivery and support client retention through...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$191K - $258K *

Shape the future of global safety by leading the development and submission of periodic aggregate safety reports. Drive compliance and collaboration across teams while managing a diverse global team t...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$263K - $325K *

Advance your career by building and leading the pharmacovigilance function from the ground up. In this pivotal role, you'll oversee drug safety operations, collaborate with cross-functional teams, and...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$116K - $145K *

Unlock potential by leading payer negotiations and expanding access across commercial, Medicare, and Medicaid sectors. Drive strategic partnerships and ensure compliance while maximizing patient acces...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$165K - $185K *

Lead drug substance activities in process chemistry, driving projects from early to late phases. Collaborate with cross-functional teams to ensure successful manufacturing and regulatory submissions...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$112K - $140K *

Transform product quality management by leading complaint intake, investigation, and resolution processes. Collaborate with cross-functional teams to ensure compliance and enhance patient safety while...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Engage healthcare professionals and thought leaders by driving scientific discussions, supporting clinical research, and facilitating impactful medical strategies in the rare disease liver portfolio w...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$131K - $177K *

Drive innovative influencer strategies that amplify engagement and shape external narratives, collaborating across departments to elevate corporate reputation and patient storytelling in a highly dyna...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Transform your career by driving oncology product success and building impactful relationships with healthcare professionals. Leverage your expertise to enhance patient access and deliver innovative s...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$190K - $225K *

Empower commercial strategies by building relationships with key thought leaders in rare neurological diseases, capturing insights to inform brand development and launch planning, and ensuring impactf...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$215K - $240K *

Shape the future of commercial operations by leading strategy, workflows, and data integration. Collaborate with senior leaders to enhance brand performance and drive operational excellence across cro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$285K - $385K *

Lead regulatory due diligence for clinical/commercial assets, assessing risks and strategies for licensing, acquisitions, and partnerships. Collaborate across teams to ensure regulatory integration in...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.