Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$176K - $220K *

Elevate innovation by designing and implementing scalable AI solutions that drive business transformation. Collaborate with diverse teams to harness AI's potential and deliver measurable results while...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Join a dynamic team as a Virtual Desktop Infrastructure Engineer, where you'll design and implement secure communication solutions for classified environments, ensuring compliance with DoD cybersecuri...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$90K - $130K *

Drive sales growth in the Midwest by managing customer relationships, developing strategies, and coordinating sales activities. Collaborate with teams to ensure customer satisfaction and achieve terri...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$151K - $309K *

Lead the charge in transforming care agent tools, enhancing system reliability and performance. Collaborate with cross-functional teams to design and implement solutions that streamline support proces...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$190K - $304K *

Drive operational excellence in managing merchant liens and levies compliance. Build a specialized team, establish governance frameworks, and ensure effective collaboration across departments to creat...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$114K - $145K *

Shape your career as a Data Engineer, transforming raw data into impactful systems. Collaborate with stakeholders, optimize data architecture, and drive efficiency through automation while managing co...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $180K *

Join a team that's dedicated to creating clear technical content that empowers engineers and product managers. Collaborate closely with engineering teams to translate complex concepts into accessible...

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$193K - $309K *

Innovate by leading the development of scalable features for our Sports & Entertainment platform. Collaborate across teams to enhance customer experiences and drive Toast's success while mentoring fel...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Explore new territories and drive growth by leading business development initiatives. You'll analyze customer needs, manage sales forecasts, and implement strategies to maximize revenue while providin...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Join a team that's dedicated to delivering high-quality construction management for airport projects. Oversee planning, design, and execution while ensuring client satisfaction and adherence to safety...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$73K - $88K *

Drive financial stewardship and risk management by supporting the Finance Manager in enhancing financial systems and processes, ensuring compliance, and delivering effective solutions for humanitarian...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Join a team that's dedicated to delivering compassionate orthopedic care across clinic, surgical, and inpatient settings. Engage with patients throughout their recovery journey while collaborating in...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$165K - $175K *

Lead global clinical trials, managing cross-functional teams to ensure project success across multiple therapeutic areas while driving operational excellence and best practices in clinical project man...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Staffing

$115K - $127K *

Join a team that's dedicated to advancing oncology research by monitoring clinical trials, ensuring compliance, and supporting investigative sites throughout the trial lifecycle. Your expertise will d...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Staffing

$70K - $110K *

Champion the implementation and support of Windows Server environments, ensuring optimal performance and security across diverse customer infrastructures while collaborating with technical teams and s...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Technical Services

$130K *

Elevate your career by providing clinical education and support, collaborating with healthcare professionals to enhance device adoption and usage, while ensuring effective communication and training i...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$127K - $159K *

Drive statistical leadership in oncology clinical development, guiding study design, analysis, and regulatory submissions. Collaborate with cross-functional teams to ensure high-quality deliverables a...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive innovative strategies in generative engine optimization, leading client accounts and teams to enhance visibility and authority in AI-driven search landscapes while ensuring measurable outcomes a...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Join a dynamic team to lead and execute innovative power generation projects, focusing on natural gas and renewable energy. Mentor engineers, manage client relationships, and drive design excellence i...

2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$83K - $93K *

Join a team that's dedicated to delivering exceptional nursing care in a 5-Star-rated facility. As a Weekend RN Supervisor, you'll oversee nursing staff, ensure quality care, and maintain a safe envir...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Champion editorial excellence by driving content development and strategy for health services journals. Collaborate with diverse teams and stakeholders to ensure high-quality, impactful publications w...

2 days ago

  •   5 - 7 years exp.  •   Media

$80K - $93K *

Grow your career with a dynamic Finance team as a Staff Accountant, supporting financial operations for R&D programs and USG contracts. Collaborate across departments to ensure accurate financial reco...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in transforming water treatment solutions by overseeing design, project delivery, and team development. Drive profitability and operational excellence while managing complex projects f...

2 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$120K - $145K *

Advance healthcare solutions by developing scalable ML systems, collaborating with cross-functional teams, and driving innovative AI methodologies to enhance patient outcomes and optimize operational...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by driving pricing excellence and delivering actionable insights. Collaborate cross-functionally to enhance pricing strategies, optimize performance, and support revenue growth in a d...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.