Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$152K - $231K *

Drive the technical narrative for a cutting-edge platform, translating complex architecture into compelling stories for diverse audiences. Collaborate across teams to enhance product demonstrations an...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$150K - $258K *

Lead a dynamic team to drive enterprise-wide transformation, integrating complex project management with strategic execution. Oversee the development of an AI-enabled contracting capability, ensuring...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$112K - $338K *

Elevate your career by leading transformative initiatives in the insurance brokerage sector. Collaborate with senior executives to drive large-scale business and technology programs, ensuring measurab...

Today

  •   8 - 10 years exp.  •   Business Services

$112K - $338K *

Join a team that's driving transformation in the insurance brokerage sector. Lead multidisciplinary initiatives, partner with senior executives, and shape strategies that integrate technology and busi...

Today

  •   8 - 10 years exp.  •   Business Services

$90K - $105K *

Join a team that's dedicated to enhancing student services and special education. Lead district-wide initiatives, ensure compliance with regulations, and foster inclusive environments for all learners...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$130K - $150K *

Lead client engagements and develop executable strategies that drive business transformation. Collaborate with senior leaders to uncover opportunities, define success, and ensure strategic initiatives...

Today

  •   5 - 7 years exp.  •   Information Technology

$225K - $265K *

Lead the charge in developing a high-performing engineering team focused on firewall validation and security. Drive collaboration across technical and product teams while fostering an inclusive enviro...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$72K - $117K *

Join a dynamic team to plan, create, and maintain databases, enhancing departmental activities through research, analysis, and support. Collaborate with stakeholders to improve data quality and stream...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$75K - $125K *

Elevate your career by onboarding customers and driving their success through strategic reviews and relationship building. Collaborate with teams to align offerings and ensure a positive experience wh...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$72K - $108K *

Elevate your career by providing tailored financial planning and investment solutions. As a key advisor, you'll build client relationships, deliver exceptional service, and drive growth while navigati...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Join a dynamic team to enhance hybrid infrastructure, ensuring system reliability and security across diverse environments. Collaborate with cross-functional teams to implement solutions and optimize...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$115K - $130K *

Empower client success by managing accounting projects and implementations. Drive efficiency through process improvements and AI tools while ensuring accurate, timely deliverables. Collaborate with te...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$91K - $169K *

Join a team that's dedicated to designing and developing innovative software solutions. Collaborate on integration and testing, ensuring high standards throughout the software development life cycle w...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$210K - $331K *

Drive scientific exchange and research initiatives as a key liaison between the scientific community and the organization, enhancing understanding of therapeutic areas and supporting clinical developm...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$107K - $135K *

Shape your career by providing engineering solutions for underground mining equipment, collaborating with teams to enhance product functionality, and ensuring compliance with safety regulations. Your...

Reposted today

  •   Less than 5 years exp.  •   Energy & Utilities

$80K - $95K *

Engage with customers to drive sales growth by mastering product knowledge, building relationships, and executing project pursuits. Collaborate with teams to maximize opportunities and deliver excepti...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$69K - $104K *

Unlock potential by leading financial reporting and investment oversight for a key retirement plan. Collaborate with teams to ensure accurate accounting and compliance while mentoring junior staff in...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$119K - $167K *

Lead the charge in evolving our cloud infrastructure and CI/CD systems. As a Senior DevOps Engineer, you'll enhance security, reliability, and operational efficiency while mentoring a team and ensurin...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$141K - $166K *

Advance your career by managing a portfolio of high-capacity donors, developing tailored engagement strategies, and collaborating with leadership to secure major gifts that support our mission in the...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $150K *

Transform production services with a robust Site Reliability Engineering approach. Collaborate with teams to enhance availability, resiliency, and operational automation while driving continuous impro...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$110K - $150K *

Join us to enhance the reliability and performance of our 24/7 SaaS platform. Collaborate with cross-functional teams to implement engineering practices that drive operational excellence and continuou...

Philadelphia, PARemote

Today

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Empower your career by driving innovative application development in engineered materials. Collaborate across teams to enhance product offerings in building and construction and electrical markets, en...

Today

  •   5 - 7 years exp.  •   Business Services

$160K - $200K *

Lead the development and execution of data management strategies, ensuring effective governance and utilization of data assets across the organization. Collaborate with stakeholders to enhance data pr...

Today

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$170K - $200K *

Lead the development and execution of data management strategies, ensuring effective governance and utilization of data assets across the organization. Collaborate with stakeholders to enhance data pr...

Today

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$77K - $202K *

Shape the future of healthcare by driving payer platform modernization. As a Senior Associate, you'll analyze complex issues, manage workstreams, and mentor junior team members while enhancing client...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.