Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$190K - $300K *

Transform the future of cancer treatment by leading global marketing strategies for a groundbreaking bispecific antibody. Collaborate across teams to drive insights, launch readiness, and commercial s...

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$129K - $203K *

Innovate your career by leading digital transformation in clinical supply chains. Drive data engineering, build custom applications, and implement AI solutions to enhance operational efficiency and in...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$156K - $247K *

Lead the charge in developing strategic forecasts and insights, collaborating across functions to drive marketing strategies and enhance business performance in a dynamic, matrixed environment...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$106K - $167K *

Engage with healthcare providers to enhance immunization rates through education and support. Collaborate with internal teams to address customer needs and optimize vaccine management, ensuring adhere...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$129K - $203K *

Support supply planning for vaccines by collaborating with cross-functional teams to optimize inventory and meet customer demand. Drive strategic decision-making and enhance supply chain processes wit...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $184K *

Transform manufacturing automation by troubleshooting complex systems, ensuring compliance, and driving performance improvements. Collaborate with teams to enhance operational efficiency and support r...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Optimize global Site Budgets and Payments processes, ensuring compliance and efficiency. Lead cross-functional teams to enhance operational excellence, drive continuous improvement, and foster collabo...

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Lead the transformation of scientific data management by driving the Signals strategy, enhancing digital capabilities, and fostering collaboration across teams to deliver actionable insights and impro...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$210K - $331K *

Join a team that's dedicated to advancing scientific exchange and research. As a key liaison, you'll engage with scientific leaders, enhance understanding of therapeutic areas, and support clinical tr...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $184K *

Lead the charge in optimizing contract management processes, ensuring compliance and excellence in customer service. Collaborate with cross-functional teams to drive strategic initiatives and enhance...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $184K *

Engage in automation system support to enhance manufacturing performance and ensure compliance in vaccine production. Collaborate with teams to troubleshoot issues, maintain systems, and drive continu...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Lead the global site budgeting capability for clinical trials, ensuring strategic direction, quality, and compliance. Collaborate across functions to enhance operational performance and drive innovati...

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$156K - $247K *

Optimize oncology marketing strategies by leveraging data-driven insights, collaborating with cross-functional teams, and enhancing patient engagement to maximize business impact and drive effective m...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Innovate with us to enhance web operations and design systems, driving user experience across multiple brands. Lead strategic initiatives, ensuring compliance and accessibility while collaborating cro...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Transform consumer marketing strategies for respiratory products, driving patient engagement and brand growth. Collaborate with cross-functional teams to deliver impactful campaigns and insights that...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$129K - $203K *

Architect quality systems and drive compliance for a Drug Substance capital project. Collaborate with cross-functional teams to ensure regulatory adherence and lead quality improvement initiatives whi...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Transform your career by leading innovative consumer marketing strategies for respiratory products. Collaborate with cross-functional teams to drive patient engagement and brand growth through data-dr...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$156K - $247K *

Transform patient support strategies and services to ensure effective access for patients navigating their treatment journey, fostering innovative solutions and improving overall patient experiences t...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Unlock your potential by leading strategic initiatives in global scientific content development. Collaborate with cross-functional teams to enhance oncology payer engagement and drive impactful traini...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Lead biostatistical initiatives in drug and vaccine projects, collaborating across teams to ensure effective trial designs and regulatory compliance. Drive statistical analysis and innovative research...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$255K - $402K *

Shape the future of oncology by leading strategic payer engagement and health systems initiatives. Drive execution of medical affairs plans while mentoring a high-performing team to enhance access and...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Support the implementation of global Site Budgets & Payments strategies, ensuring effective regional execution and governance. Collaborate with cross-functional teams to enhance operational excellence...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Transform operational strategy and execution across a high-impact organization, leading governance, resource management, and cross-functional alignment to drive consistent and compliant outcomes while...

North Wales, PARemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Drive strategic account management within Integrated Delivery Systems, enhancing relationships and optimizing product access across New York's healthcare landscape. Collaborate with stakeholders to ac...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $331K *

Lead the charge in safety and risk management processes, ensuring compliance and continuous improvement across departments. Collaborate with stakeholders to develop metrics and oversee pharmacovigilan...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.