Find Your Next High-Paying Job in Pennsylvania

Are you a professional seeking $100K+ jobs in Pennsylvania? You've come to the right place. Ladders is your hub for high-paying Pennsylvania jobs across a broad range of industries, including Tech, Finance, Healthcare, and more.

Unlock Opportunities in Pennsylvania

Pennsylvania, known for its rich history and diverse job market, offers a plethora if opportunities for ambitious professionals seeking high-paying jobs.

How Ladders Can Help

Whether you're looking for jobs in Philadelphia, Pittsburgh, or smaller cities within Pennsylvania, Ladders has got you covered. Our selection of $100K+ jobs in Pennsylvania is carefully curated and regularly updated. Start your job searc on Ladders today!

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $120,957

Sort By: Relevance

$220K - $240K *

Partner with us to drive our multi-year strategy for information security and IT operations. Lead and mentor a diverse team while ensuring compliance and governance across all technology functions, ma...

US-AnywhereRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$110K - $151K *

Engage with strategic customers to enhance cloud security practices and drive revenue growth. Collaborate effectively with stakeholders in a high-tech environment, steering complex engagements towards...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Manage and optimize onsite concrete and materials testing operations, ensuring quality control for a key U.S. Army Corps project. Lead laboratory personnel and testing procedures to maintain high stan...

Reposted today

  •   5 - 7 years exp.  •   Technical Services

$124K - $151K *

Serve as a pivotal Staff Pharmacist, leading pharmacy operations, ensuring patient care excellence, mentoring team members, and upholding safety standards while navigating the evolving landscape of he...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$144K - $184K *

Join an innovative engineering team to transform product delivery through AI-driven development, ensuring high standards and compliance while combining product, design, and engineering leadership acro...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$151K - $189K *

Lead the charge in implementing global tax automation systems across diverse industries, collaborating with various teams and managing projects to ensure successful requirements gathering, design, bui...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$179K - $238K *

Innovate data solutions as a Senior Staff Data Engineer. Lead cross-functional teams to enhance a robust Data Platform. Engage in system design, data analysis, and mentoring within a collaborative env...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Transform your career by driving B2B sales growth through proactive outreach, managing the full sales cycle, and providing insights on market trends. Collaborate with partners to ensure client success...

Today

  •   Less than 5 years exp.  •   Business Services

$105K - $150K *

Help us cultivate a high-performance culture by partnering with senior Engineering leaders to enhance talent strategy, manage sensitive employee relations, and drive people initiatives within complex...

Reposted today

  •   5 - 7 years exp.  •   Business Services

$123K - $170K *

Join a team that's driving innovation in healthcare architecture. Lead large projects and guide junior architects while ensuring high-quality design and compliance. Collaborate closely across teams, a...

Reposted today

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Drive HR excellence by shaping policies, enhancing employee engagement, and ensuring compliance in a dynamic organizational environment. Lead strategic initiatives to foster a thriving workplace cultu...

Today

  •   5 - 7 years exp.  •   Healthcare

$122K - $212K *

Help us lead compliance monitoring initiatives, improve operations, and execute training programs across North America. You'll drive risk analysis, enhance team performance, and collaborate with stake...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$109K - $174K *

Lead the execution of clinical trial activities, ensuring operational delivery and vendor management while overseeing regional coordination. Foster team productivity and drive process improvements in...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$109K - $174K *

Contribute to the success of clinical trials by managing study-level activities and vendor oversight. Drive strategic alignment and operational delivery across regions, ensuring all trial phases are e...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $100K *

Partner with us to establish and manage a dynamic Condo Desk, overseeing all aspects from documentation review to project certification, ensuring compliance with agency and investor guidelines while d...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$163K - $218K *

Empower your career by leading SLED capture and proposal strategies. Drive growth and engage diverse teams in this pivotal role, shaping public sector outcomes through innovative procurement and partn...

US-AnywhereRemote

Reposted today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Empower our project teams by developing innovative process piping designs in a dynamic 3D CAD environment, collaborating closely across disciplines to deliver cutting-edge design solutions across vari...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $105K *

Drive excellence in electrical BIM coordination for mission-critical projects, ensuring efficient modeling, clash detection, and execution within multifaceted teams to enhance construction success and...

Reposted today

  •   Less than 5 years exp.  •   Real Estate & Construction

$150K - $180K *

Accelerate your career by spearheading business development in the Hi-Tech sector. Partner with cross-functional teams to build and qualify a robust pipeline, engaging with key industry players to sec...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Join a team that's redefining healthcare economics by analyzing costs and outcomes to enhance clinical strategies. Utilize advanced data analytics to drive actionable insights and improved patient car...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$124K - $238K *

Lead the charge in crafting compelling narratives for external communications. Collaborate with a dynamic team to shape press releases that resonate with customers, media, and stakeholders, enhancing...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Business Services

$170K - $215K *

Shape the future of brand strategy by leveraging insights, collaborating with teams, and delivering impactful campaigns that drive brand results and inspire trust in clients...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$66K - $105K *

Join our team to provide exceptional nursing care, ensuring patient safety and effective communication while administering home infusion therapies and coordinating family support in a home care settin...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Oversee and coordinate electrical construction activities, ensuring compliance with specifications, codes, and safety standards while managing subcontractors and promoting effective collaboration acro...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Lead the charge in overseeing mechanical construction activities, ensuring compliance with safety and quality standards. Collaborate with project teams to manage installations from pre-construction to...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What industries in Pennsylvania offer the most $100K+ jobs?question toggle

    There are numerous industries in Pennsylvania offering $100K+ jobs, including Tech, Finance, Healthcare, and more.

  • Can I find $100K+ jobs all over Pennsylvania on Ladders?question toggle

    Yes, Ladders list high-paying jobs in all areas of Pennsylvania including in big cities like Philadelphia and Pittsburgh, as well as smaller cities.

  • How often are the $100K+ job listings in Pennsylvania updated on Ladders?question toggle

    The $100K+ job listings in Pennsylvania are updated regularly to ensure that our users have access to the most current opportunities.