Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$95K - $105K *

Unlock potential by providing strategic technical support to enhance retrofit sales. Collaborate with sales teams and end-users to optimize HVAC systems, identify improvement opportunities, and drive...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$170K - $200K *

Drive market and competitive intelligence initiatives to enhance strategic decision-making across teams. Build a high-performing function that delivers insights on customer behavior, market trends, an...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $135K *

Lead the charge in developing and implementing global safety standards and compliance initiatives. Collaborate with cross-functional teams to foster a proactive safety culture, ensuring the health and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$80K - $95K *

Elevate patient care by serving as a vital advocate and resource for oncology patients and families, ensuring seamless access to multidisciplinary services and support throughout their treatment journ...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $140K *

Engage with clients to optimize their cybersecurity services investment, ensuring success through strategic relationship management, education, and program enhancement. Drive customer preparedness and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by leveraging your Salesforce expertise to design, build, and review secure, scalable solutions. Collaborate with clients and teams to ensure seamless integrations and effective deliv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $94K *

Unlock potential by joining a dynamic team that supports military transitions into civilian roles. Gain hands-on experience in IT project management while collaborating with industry leaders to enhanc...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$83K - $104K *

Grow your career with a dynamic team focused on exceptional patient care. Leverage your skills in a modern practice environment while enhancing oral health and building lasting patient relationships...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Shape complex, cross-functional programs that drive enterprise transformation, focusing on Customer Data Platform implementation and AI initiatives. Collaborate with diverse teams to ensure strategic...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$190K - $200K *

Elevate operational excellence by leading transformation initiatives and optimizing Shared Services. Collaborate with senior leaders to drive measurable improvements in productivity, cost efficiency...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Empower the supply chain by leading complex buying activities, managing vendor relationships, and ensuring timely delivery of high-quality materials to meet production needs and customer demands...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Lead the charge in managing complex litigated commercial liability claims, ensuring compliance and effective communication while driving resolution strategies in a dynamic, paperless environment...

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$175K - $210K *

Unlock potential by leading strategic business development initiatives that connect biopharmaceutical executives with tailored commercial solutions. Drive growth through relationship-building and inno...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$104K - $114K *

Join a dynamic team as a Dental Hygienist, providing exceptional patient care through cleanings, assessments, and education in a collaborative environment focused on comfort and advanced treatments fo...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$119K - $140K *

Drive global marketing strategy by executing integrated campaigns that enhance revenue through collaboration with cross-functional teams, while optimizing performance with data-driven approaches to ma...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $105K *

Optimize software quality by collaborating with cross-functional teams to ensure seamless digital experiences. Leverage automation and modern testing practices to enhance web and mobile applications f...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Transportation

$110K - $130K *

Empower innovation by partnering with data science to build and maintain robust ML pipelines. Drive automation and observability in production systems, ensuring reliable match data at scale while coll...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$148K - $222K *

Elevate global pricing and access strategies to maximize commercial success in oncology, epilepsy, and sleep disorders. Collaborate cross-functionally to shape market insights and drive impactful deci...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $90K *

Join a dynamic team to manage commercial roofing projects from start to finish, ensuring timely execution and adherence to specifications while collaborating with various stakeholders to deliver high...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Champion operational excellence by leading production teams and driving continuous improvement initiatives. Oversee manufacturing processes to ensure quality and efficiency, while fostering a collabor...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$86K - $144K *

Transform complex data into intelligent AI systems that enhance workflows. Collaborate within an Innovation Squad to integrate AI capabilities and deliver high-quality features while supporting seamle...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$94K - $266K *

Join a team that's shaping the future of AI solutions by developing scalable, innovative applications within the Salesforce ecosystem. Collaborate with clients to deliver strategic initiatives and exp...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive innovative civil engineering projects through leadership, design, and project management. Collaborate with multi-disciplinary teams to exceed client expectations in site development and water re...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Technical Services

$181K - $216K *

Empower the future of people operations by aligning strategy with business goals. Lead a dynamic team across HR functions, driving engagement, compliance, and organizational design while fostering a c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$75K - $94K *

Join a team that's redefining event management by overseeing AV production for diverse corporate clients. You'll be the key liaison, ensuring seamless execution and fostering strong relationships whil...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.