Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$171K - $383K *

Unlock potential by leading AI-driven transformations in Life Sciences commercial operations. Drive innovative solutions, manage client engagements, and build high-performing teams to enhance data and...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$171K - $383K *

Champion transformative AI and data solutions in Life Sciences, leading client engagements and high-performing teams to drive commercial operations innovation and strategy execution across the industr...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$86K - $124K *

Champion project success by leading SAP implementations, managing teams, and ensuring alignment with client needs. Drive agile methodologies, facilitate collaboration, and deliver innovative solutions...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $155K *

Elevate the narrative of a leading B2B company by crafting compelling content that drives organic growth. Own the content calendar, collaborate cross-functionally, and transform complex ideas into eng...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$204K - $285K *

Innovate solutions for utility clients by leveraging your 15+ years of regulatory finance expertise. Lead projects, conduct cost studies, and provide expert testimony while mentoring junior staff and...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Energy & Utilities

$161K - $230K *

Join a team that's shaping the future of energy by providing expert consulting on gas pipelines and FERC regulations. Lead client engagements, manage deliverables, and drive business development while...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$199K - $230K *

Drive innovation by deploying and optimizing cloud infrastructure across federal environments. Leverage your expertise in AWS, Kubernetes, and automation tools to enhance platform scalability and secu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Transform the Customer Success landscape by leading a new NORAM scaled team, defining strategies for global customer engagement, and ensuring personalized experiences at scale across diverse segments...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Join a dedicated team to deliver exceptional pharmaceutical care, ensuring safe and effective medication therapy while enhancing patient outcomes and quality of life through evidence-based practices a...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $137K *

Elevate healthcare transformation by coaching clinicians and leaders to optimize operational excellence and improve patient outcomes through effective EHR utilization and workflow redesign. Drive chan...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$193K - $241K *

Lead and oversee Medical Information teams, ensuring high-quality service delivery and compliance. Drive strategic initiatives, manage resources, and collaborate cross-functionally to enhance operatio...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$107K - $195K *

Lead the charge in developing advanced platforms that automate operations and enhance AI-driven interactions. This hands-on role combines technical leadership with coding, mentoring, and ensuring comp...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$87K - $157K *

Unlock your potential as a mid-level Software Engineer, driving innovation in AI-enabled platforms. Collaborate with a diverse team to build intelligent agents and backend services, enhancing automati...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$107K - $195K *

Lead multidisciplinary teams to deliver high-voltage substation EPC projects, ensuring integrated design and technical excellence from concept to energization while mentoring future engineering leader...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$73K - $132K *

Manage and oversee the implementation of the IHS EDR program, ensuring successful deployment and client satisfaction through coordination with vendors and internal teams while handling multiple projec...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$80K - $95K *

Shape the future of cancer treatment by collaborating with experts to create individualized radiation therapy plans. Leverage advanced tools and techniques in a supportive, fully remote environment fo...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $110K *

Transform product ideas into reality by leading design, testing, and execution. Collaborate with cross-functional teams to solve engineering challenges and ensure high-quality solutions that enhance c...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Unlock potential by providing advanced technical leadership for magnetic-bearing water-cooled chillers, driving product reliability and innovation across the lifecycle while collaborating with cross-f...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $130K *

Drive innovative electrical designs for advanced HVAC chiller systems, ensuring compliance and performance in commercial environments. Collaborate with sales and engineering teams to deliver tailored...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Transform compressor technology by leveraging advanced aerodynamic design, simulation, and data-driven methods. Collaborate on innovative HVAC solutions, enhancing performance and efficiency while dri...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$76K - $114K *

Join us to design and implement fire sprinkler systems, ensuring compliance and efficiency through detailed CAD drawings, hydraulic calculations, and collaboration with installation teams for optimal...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$104K - $156K *

Champion project success by leading complex data center construction initiatives, ensuring timely delivery, budget adherence, and compliance with safety standards while fostering collaboration across...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$104K - $156K *

Elevate your career by leading complex data center projects, ensuring timely execution and profitability while collaborating with cross-functional teams to drive innovative solutions and maintain high...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$75K - $110K *

Shape the future of electrical design by overseeing innovative projects, conducting analyses, and collaborating with global teams to enhance air-cooled chiller systems and components, ensuring optimal...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$89K - $105K *

Deliver compelling marketing and policy content that enhances brand voice and reputation. Collaborate with teams to translate complex topics into clear narratives, ensuring high-quality, timely materi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.