Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,459

Sort By: Relevance

$85K - $102K *

Elevate project outcomes by coordinating with clients and teams, performing engineering calculations, and transforming designs into technical specifications for diverse public and private projects...

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$95K - $115K *

Lead and optimize Material Center operations, ensuring efficient inventory management, production support, and team development while driving continuous improvement and safety standards across all fun...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $95K *

Drive innovation in LED display design, enhancing quality and performance. Collaborate with global teams to support product lifecycle from conception to installation, ensuring excellence in engineerin...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$130K - $155K *

Drive business growth by leading consulting and system studies for T&D infrastructure, focusing on data centers. Engage with industry leaders and ensure high-quality technical solutions while supporti...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $130K *

Empower your career by leading sales strategies across the US. Collaborate with a dynamic team to drive growth, develop client relationships, and deliver impactful presentations while navigating indus...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $200K *

The Senior Consultant - Clinical Operations will lead the implementation of Clinical Operations applications to enhance efficiency in Clinical Trials for life sciences clients. This role involves mana...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$142K - $224K *

Join us in advancing clinical data standards and governance. Lead teams, mentor staff, and ensure compliance with industry regulations while driving high-quality data collection processes across thera...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Champion scientific exchange and research initiatives in gastrointestinal immunology, engaging with key scientific leaders to enhance understanding and support clinical trials while fostering an inclu...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$156K - $247K *

Champion advanced analytics and AI solutions to drive strategic insights for pharmaceutical marketing. Collaborate with cross-functional teams to enhance decision-making and optimize brand performance...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Join us to lead innovative marketing strategies for our HIV treatments portfolio. Drive brand execution and mentor a high-performing team while collaborating across functions to optimize promotional i...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Champion the evolution of digital marketing by leading media capabilities and agency management. Drive strategic initiatives, foster partnerships, and enhance operational excellence to maximize value...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$129K - $203K *

Advance therapeutic discovery by applying computational chemistry and data science. Collaborate globally to design innovative drug candidates and develop predictive models using AI/ML techniques, enha...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $110K *

Unlock your potential as you drive strategic growth in K-12 special education markets. Lead complex sales cycles, build trusted relationships, and shape innovative solutions that enhance educational o...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$117K - $184K *

Drive patient access initiatives by collaborating with healthcare professionals and organizations. Analyze access trends, educate on reimbursement processes, and support patient assistance programs to...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Drive impactful HCP marketing strategy in Crohn’s disease, shaping launch readiness through data-driven insights. Collaborate across teams to ensure cohesive engagement and effective resource allocati...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $137K *

Join a dynamic team to enhance manufacturing automation, ensuring compliance and quality in vaccine production. Leverage your expertise to troubleshoot, innovate, and implement strategies that drive e...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$129K - $203K *

Lead the charge in regulatory operations by overseeing submissions to the FDA, ensuring compliance with regulations, and driving analytics to enhance operational performance while collaborating with c...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$156K - $247K *

Drive data-driven insights and analytics for vaccine market strategies, collaborating with global teams to enhance brand growth and commercial objectives. Leverage advanced analytics and AI to inform...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $184K *

Shape the future of patient access by collaborating cross-functionally to address healthcare professionals' needs, ensuring timely therapy access while navigating reimbursement processes and complianc...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Lead the charge in shaping digital tech transfer and knowledge management strategies. Drive execution with a multi-disciplinary team to enhance manufacturing capabilities and ensure seamless integrati...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Lead the charge in developing innovative patient engagement strategies that enhance our support offerings, collaborating closely with cross-functional teams and external partners to drive initiatives...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Lead the evolution of laboratory orchestration platforms, combining technical expertise with strategic vision to enhance automation and integration across scientific operations, ensuring scalable and...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $190K *

Deliver innovative solutions by acquiring Fortune 500 clients, leading complex sales cycles, and building executive relationships. Drive value through AI insights and strategic partnerships, ensuring...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$142K - $224K *

Drive strategic launch excellence for Immunology, focusing on IBD. Collaborate with cross-functional teams to ensure integrated planning, readiness, and execution, enhancing decision-making and operat...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$106K - $167K *

Lead safety initiatives for high-risk work and machinery across multiple sites, ensuring compliance and risk mitigation. Collaborate with cross-functional teams to enhance safety protocols and drive c...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.