Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$110K - $218K *

Unlock potential by driving data and AI solutions for upstream oil and gas operations. Collaborate with experts to enhance decision-making through innovative analytics and data engineering, contributi...

6 days ago

  •   Less than 5 years exp.  •   Business Services

$110K - $218K *

Unlock potential by leading data-driven solutions for upstream oil and gas operations. Collaborate with cross-functional teams to enhance decision-making through advanced analytics, AI, and data engin...

6 days ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Transform your career by leading lean initiatives to optimize processes, eliminate waste, and foster a culture of continuous improvement. Drive measurable results through effective project management...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Drive advanced application expertise and technical leadership in Epic Beaker solutions. Collaborate with stakeholders to design, implement, and optimize laboratory workflows while mentoring team membe...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$200K - $225K *

Lead the charge in optimizing property tax strategies across North America, ensuring compliance and minimizing liabilities. Collaborate cross-functionally to drive impactful decisions and enhance tax...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's shaping the future of aftermarket solutions by driving growth through strategic customer engagement and innovative lifecycle management. Collaborate cross-functionally to enhance pr...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$73K - $100K *

Elevate workforce planning by transforming data into impactful insights. Partner with leaders to build strategic forecasting tools and measure performance metrics, contributing to operational efficien...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $143K *

Shape the future of pharmacy software by leading product strategy, managing cross-functional teams, and driving improvements in patient outcomes and business results through innovative product managem...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Drive the evolution of learning technology by leading strategy, governance, and continuous improvement of the LMS and learning platforms. Collaborate with stakeholders to enhance learner experiences a...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $118K *

Lead the charge in managing complex healthcare projects, ensuring timely delivery and budget adherence while coordinating cross-functional teams and mitigating risks for strategic initiatives...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $110K *

Champion growth by developing strategic partnerships in international airfreight. Drive profitable expansion through client engagement, leveraging expertise in logistics solutions to enhance market pr...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Transportation

$210K - $250K *

Join a dynamic team as you lead outpatient sleep services, combining patient care with operational oversight. Drive quality and accreditation while engaging in academic pursuits within a comprehensive...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Help us shape the future of mental health care by providing compassionate, evidence-based therapy to diverse populations. Collaborate with a dedicated team to enhance patient outcomes in a supportive...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$79K - $83K *

Help us advance hearing solutions by providing clinical and sales support across North and Central Virginia. Join a dedicated team and develop expertise in cochlear implants while building strong cust...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Elevate your career with a dynamic team focused on innovative accounting solutions. Lead financial processes, ensure compliance, and drive efficiency in a fast-paced environment while collaborating cr...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$102K - $163K *

Shape the future of respiratory care by leading systems engineering efforts for innovative medical devices. Collaborate cross-functionally to ensure product safety, reliability, and compliance while d...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $180K *

Drive impactful healthcare technology solutions through data-driven strategies, optimize customer engagements with compelling insights, and foster long-term partnerships for strategic growth...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Elevate your career by managing a dynamic team, ensuring exceptional service delivery, and fostering employee development while driving customer satisfaction across diverse sectors...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$176K - $294K *

Join a team that's driving operational excellence in Medical Affairs, enhancing strategic initiatives and project management across multiple stakeholders. Leverage your expertise to optimize processes...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$162K - $271K *

Unlock potential by leading strategic insights for a biopharmaceutical launch team, driving US forecasting, market research, and analytics integration to optimize commercial strategies and ensure alig...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $207K *

Lead and influence high-complexity projects, allocate resources, and drive innovation across the Global Business Unit while developing talent and strategic partnerships to achieve business goals effec...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$162K - $271K *

Unlock potential by leading P2P and field engagement strategies, driving impactful connections with hematologists and oncologists through innovative programs and insights, while collaborating closely...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $294K *

Join a team that's driving innovative clinical studies for novel therapies, leading protocol development and collaborating with cross-functional partners to ensure successful execution and delivery of...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$176K - $294K *

Contribute to building impactful relationships with Hematology thought leaders, crafting engagement strategies and insights to optimize Pfizer’s Hematology portfolio. Collaborate cross-functionally to...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $207K *

Partner with us to drive data strategy and management for Oncology brands, ensuring data integrity and governance while aligning with commercial objectives and enhancing analytics capabilities across...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.