Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$80K - $95K *

Engage with patients as a Virtually Integrated Care RN, providing essential remote support and care coordination. Utilize advanced clinical skills to assess needs, develop care plans, and enhance pati...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Optimize the Innovation portfolio by leading high-impact projects, collaborating with senior leaders, and driving strategic initiatives. Your role will ensure seamless operations and foster growth in...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Advance your career by leading project teams in civil engineering, managing budgets, schedules, and client interactions while ensuring quality control and mentoring staff in a dynamic waste management...

6 days ago

  •   8 - 10 years exp.  •   Technical Services

$100K - $120K *

Shape the future of healthcare operations by leading transformative initiatives that enhance care management effectiveness, streamline workflows, and drive measurable outcomes across clinical programs...

Harrisburg, PARemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Shape the future of pharmaceutical care by evaluating medication orders, providing clinical recommendations, and collaborating with healthcare teams to enhance patient outcomes in a supportive, non-re...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $140K *

Join a dynamic team to lead complex data management projects, blending Agile methodologies with technical expertise. Drive collaboration across healthcare analytics, ensuring successful delivery and s...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$90K - $110K *

Join a dynamic team as you analyze and select risks in stop loss underwriting, driving profitable growth while collaborating with seasoned professionals to enhance your expertise and understanding of...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Lead a high-performing sales team to drive new logo acquisition and revenue growth in enterprise software. Develop strategies, foster collaboration, and engage executive customers to expand market sha...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the transformation of healthcare IT by managing ServiceNow projects, enhancing workflows, and ensuring seamless integration. Collaborate with cross-functional teams to deliver innovative solution...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $175K *

Join a team that's dedicated to managing complex professional liability claims, focusing on legal malpractice. Leverage your expertise to evaluate coverage, negotiate outcomes, and ensure timely reser...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$89K - $104K *

Advance patient communication and swallowing abilities by designing and implementing tailored rehabilitation plans. Collaborate with peers and educate patients and caregivers to foster independence an...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $236K *

Lead the charge in consumer engagement and growth strategy, driving awareness and deepening user connections across channels. Collaborate cross-functionally to optimize campaigns that inspire action a...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$90K - $110K *

Join a team that's driving enterprise growth by building relationships and closing new business. This proactive sales role focuses on acquiring customers for innovative workforce development solutions...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$275K - $340K *

Drive growth by leading sales and customer success teams, refining strategies, and optimizing processes. Shape the commercial landscape while mentoring talent and ensuring high-value customer relation...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$199K - $269K *

Shape patient affordability strategies by leading a dynamic team focused on co-pay programs and innovative solutions. Collaborate cross-functionally to enhance operations, optimize performance, and dr...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$191K - $258K *

Shape the future of global safety by leading the development and submission of periodic aggregate safety reports. Drive compliance and collaboration across teams while managing a diverse global team t...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $120K *

Join a team that partners with Investment Management to enhance audit processes and risk assessments. Contribute to local and global audits, evaluate compliance, and execute data analytics for effecti...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $110K *

Shape people strategies by partnering with business leaders to drive growth, enhance employee experience, and foster a culture of performance, inclusion, and learning across multiple sites or countrie...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Advance your career by leading quality improvement projects and collaborating across teams to enhance processes. Utilize data analysis to drive success and ensure adherence to safety and quality stand...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Join a team that's dedicated to driving excellence in manufacturing processes. Oversee daily production operations, ensuring quality, safety, and efficiency while fostering a culture of continuous imp...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Business Services

$85K - $110K *

Partner with us to develop and optimize innovative agricultural formulations, supporting sustainable solutions from concept through testing and scale-up, while collaborating across teams to overcome t...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$96K - $125K *

Empower growth by driving sales and market share in agricultural products. Collaborate with distributors and growers to enhance crop performance while identifying new business opportunities across mul...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$85K - $100K *

Deliver advanced field service support for Promega instrumentation, ensuring installation, training, and repairs meet customer service standards. Collaborate with teams to enhance service documentatio...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in traffic and transportation engineering, conducting studies, analyses, and designs while overseeing project execution with a multidisciplinary team across diverse sectors including s...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$317K - $443K *

Engage with cross-functional teams to shape the design vision for search and feeds, leading a talented design group to enhance user discovery and community connections while driving growth and retenti...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.