Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$77K - $108K *

Drive the implementation and support of AI workload orchestration platforms, ensuring high-quality technical outcomes in client environments. Collaborate across teams to deliver reliable, secure acces...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$221K - $271K *

Drive the vision and strategy for Collections & Recovery, enhancing product delivery and leveraging advanced technologies to improve customer engagement and operational efficiency across teams and pla...

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Transform scientific workflows by designing and integrating advanced robotics and automation systems. Collaborate with cross-functional teams to enhance reliability and efficiency in laboratory enviro...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Engineer automated integration solutions for R&D robotics, enhancing workflows and reliability through hands-on design, troubleshooting, and vendor collaboration to support cutting-edge scientific adv...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Champion the design of integrated laboratory automation systems, defining workflows and standards for scientific discovery. Collaborate with cross-functional teams to enhance automation capabilities a...

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Champion the development of integrated discovery platforms as a Principal Laboratory Automation Scientist, driving scientific automation architecture and enabling autonomous laboratory workflows that...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $150K *

Empower financial excellence by providing strategic insights and operational guidance. Collaborate across teams to enhance performance, streamline processes, and drive efficiency in a dynamic logistic...

5 days ago

  •   5 - 7 years exp.  •   Transportation

$84K - $126K *

Empower your career by leading operational excellence in logistics. Drive performance, enhance quality, and foster team development while ensuring compliance with safety standards and optimizing proce...

5 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Drive transformative customer engagement and data solutions. Collaborate across teams to design and implement marketing technologies that enhance customer experiences, leveraging analytics and custome...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Lead the charge in delivering high-quality nursing care while supervising staff, ensuring compliance with regulations, and fostering professional development in a collaborative environment focused on...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $208K *

Shape the future of market access analytics by leading payer insights and reporting. Collaborate with cross-functional teams to translate complex data into strategic guidance, enhancing access strateg...

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$94K - $266K *

Unlock potential as you bridge functional requirements and technical delivery, leading solution design and integration for complex Insurance programs while mentoring junior team members and driving in...

5 days ago

  •   5 - 7 years exp.  •   Business Services

$94K - $266K *

Join a team that's redefining insurance solutions by bridging architecture and execution. You'll lead technical workstreams, support complex integrations, and mentor junior members while ensuring clar...

5 days ago

  •   5 - 7 years exp.  •   Business Services

$276K - $328K *

Transform your career by leading drug substance process strategy and execution. Collaborate cross-functionally to ensure scalable, safe, and cost-effective external manufacturing while driving continu...

5 days ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$163K - $369K *

Champion impactful negotiations by leading complex deal strategies, fostering relationships with stakeholders, and ensuring compliance for mutually beneficial outcomes. Drive training initiatives and...

5 days ago

  •   5 - 7 years exp.  •   Business Services

$163K - $369K *

Lead complex negotiations by establishing relationships with clients and stakeholders, ensuring compliance and resolving disputes while driving mutually beneficial outcomes in a dynamic environment...

5 days ago

  •   5 - 7 years exp.  •   Business Services

$255K - $345K *

Join a team that's redefining cybersecurity by integrating AI capabilities. Leverage your 15+ years of experience to drive innovation, collaborate with cross-functional teams, and deliver mission-crit...

RemoteRemote

5 days ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $170K *

Drive the evolution of Legal Operations analytics by building scalable data capabilities, modernizing reporting, integrating AI, and establishing predictive models to enhance decision-making and opera...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Join us to design and deploy enterprise wireless networks across diverse sectors. Collaborate with clients and teams to ensure project success while providing technical support and troubleshooting in...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$76K - $102K *

Join a dynamic imaging team as a Diagnostic Technologist, enhancing your skills in CT. This role involves performing diagnostic imaging procedures, ensuring high-quality patient care, and collaboratin...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Elevate your career by developing innovative solutions within the Infor LN platform. Collaborate with cross-functional teams to enhance payment processing capabilities and create seamless integrations...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Transform patient access by optimizing Epic Cadence workflows. Collaborate with clinical teams to enhance scheduling efficiency and support system improvements, ensuring seamless operations and superi...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Shape the future of IT strategy by leading high-impact initiatives and building a world-class team. Transition from traditional PMO to a dynamic Value Management Office, driving value and innovation a...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $120K *

Drive operational excellence by leading Hub programs, enhancing performance metrics, and developing Supervisors. Collaborate cross-functionally to ensure effective service delivery and continuous impr...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Shape the future of regulatory operations by driving digital transformation and optimizing content management strategies. Collaborate with cross-functional teams to enhance scalability and compliance...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.