Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$165K - $242K *

Lead the charge in driving strategic growth initiatives for a multi-billion-dollar business. Collaborate with cross-functional teams to assess market opportunities, support acquisitions, and enhance c...

5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Join us to enhance enterprise infrastructure systems through innovative design and support. You'll oversee hybrid cloud and on-premises environments, ensuring security and compliance while driving mod...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$113K - $170K *

Join a dynamic team as you drive client engagement, manage projects, and cultivate relationships to foster growth. Lead strategic initiatives, oversee operations, and ensure high-quality delivery whil...

5 days ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $150K *

Grow your career with a dynamic role managing field marketing programs that drive pipeline and ROI. Oversee 8-10+ initiatives quarterly, collaborating closely with Sales to optimize strategies and enh...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$172K - $238K *

Lead and elevate secured lending asset quality and model oversight, shaping methodologies while collaborating with cross-functional teams to ensure rigorous governance and regulatory readiness for div...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$160K - $200K *

Join a team that's dedicated to providing safe, quality anesthesia care while ensuring patient safety and comfort throughout the surgical process. Collaborate with healthcare professionals to deliver...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Elevate patient care by providing safe, quality anesthesia and monitoring throughout surgical procedures. Collaborate with medical staff to ensure optimal outcomes and maintain high standards of profe...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$200K - $235K *

Lead the charge in advancing cancer research by building key relationships, executing impactful territory plans, and providing educational insights to healthcare professionals in Immuno-Oncology acros...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$240K - $300K *

Transform the Environmental Health & Safety landscape by leading national programs, ensuring compliance, and driving cultural change across critical facilities. Collaborate with teams to enhance safet...

5 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$125K - $150K *

Unlock insights as you analyze user data to shape strategy and product priorities. Collaborate with teams to create compelling narratives and dashboards that drive decision-making and enhance our unde...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$119K - $144K *

Shape the future of organizational consulting by leading complex client engagements, transforming data into actionable insights, and influencing C-suite decisions while fostering team development and...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$125K - $145K *

Unlock potential by bridging IT policy and strategy with organizational goals. Manage policy governance for a federal CIO organization, ensuring alignment with federal standards and overseeing a compr...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Elevate your career by driving strategic marketing initiatives that enhance brand presence and boost sales. Lead multi-channel campaigns, foster partnerships, and leverage data to achieve measurable b...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$91K - $137K *

Empower your career by managing clinical research sites, ensuring patient safety, and maintaining data integrity. Collaborate with teams to oversee study implementation and monitoring, while enhancing...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$154K - $258K *

Lead the charge in project management excellence for Power Transmission, overseeing governance, financial performance, and risk management across a diverse portfolio. Drive operational success and fos...

5 days ago

  •   11 - 15 years exp.  •   Business Services

$181K - $225K *

Lead the charge in operationalizing complex clinical studies globally, collaborating with cross-functional teams to enhance proposal development and manage global lab relationships, ensuring strategic...

United StatesRemote

Reposted 5 days ago

  •   11 - 15 years exp.  •   Healthcare

$162K - $243K *

Shape the future of clinical research by leading cross-functional teams to optimize project delivery, ensuring quality and compliance while managing resources and budgets effectively across global cli...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$170K - $195K *

Elevate your career by developing and executing impactful content strategies that drive demand generation. Collaborate across teams to create high-quality assets that engage buyers and enhance busines...

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Lead focused psychological evaluations for Veterans, ensuring high-quality assessments. Collaborate within a multidisciplinary team to support VA disability claims, while maintaining independent clini...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $105K *

Engage veterinary customers by leveraging consultative sales techniques to drive diagnostic revenue growth. Build strong relationships, educate staff, and collaborate with teams to deliver tailored so...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Optimize manufacturing efficiency and capacity through advanced industrial engineering techniques, including factory modeling, process improvement, and project leadership. Drive data-driven decisions...

5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$108K - $201K *

Partner with us to ensure compliant content management, overseeing the entire lifecycle from creation to approval. Collaborate cross-functionally to mitigate risks and enhance operational efficiency i...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Elevate regulatory intelligence by translating complex changes into actionable insights, guiding product strategy and marketing efforts while establishing thought leadership and fostering relationship...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Join a dynamic team to lead and optimize test cell operations, ensuring safety and excellence in delivery. Influence continuous improvement, engage in problem-solving, and build a skilled team to meet...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$106K - $153K *

Lead creative initiatives across multiple accounts, inspiring teams to deliver exceptional concepts while ensuring client satisfaction and strategic alignment. Manage projects from inception to comple...

5 days ago

  •   8 - 10 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.