Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$91K - $129K *

Lead the charge in financial excellence by managing treasury operations, ensuring compliance with accounting standards, and providing strategic insights to enhance operational efficiency and support e...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Transportation

$159K - $254K *

Drive impactful software development to enhance customer delivery experiences. Collaborate with cross-functional teams to design resilient systems that support real-time order tracking and efficient p...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$250K - $300K *

Join a team that's dedicated to advancing cardiothoracic surgery through innovative patient care, organ procurement, and surgical treatments, while managing complex cases in a collaborative environmen...

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Champion the commercial contracting process by drafting, reviewing, and negotiating agreements. Collaborate with cross-functional teams to streamline workflows and ensure compliance while supporting t...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Transform clinical research practices by guiding study design and analysis. Collaborate with cross-functional teams to deliver key insights and evidence that drive product innovation in the healthcare...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $180K *

Shape the future of fraud risk management by leading a high-performing operations team, enhancing investigative practices, and influencing fraud strategy within a dynamic digital investing environment...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$65K - $114K *

Advance your career by overseeing undergraduate admissions advising and recruitment. Collaborate with leadership to implement policies, evaluate applications, and enhance outreach to diverse student p...

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $146K *

Unlock potential by developing and supporting complex web and mobile applications. Collaborate with cross-functional teams to deliver robust solutions, ensuring high performance and reliability while...

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$135K - $176K *

Join us in transforming patient care as you lead a dedicated pharmacy team, ensuring exceptional service and compliance while fostering a culture of excellence and compassion in a dynamic retail envir...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Unlock growth in Federal, Aerospace, and Defense sectors by managing strategic partnerships to enhance revenue and market presence. Collaborate across teams to drive pipeline and customer success with...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$80K - $95K *

Lead clinical excellence as a Senior Clinician, enhancing IV Therapy practices, staff education, and quality initiatives across multiple locations. Collaborate with healthcare teams to improve patient...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Innovate AI-driven business applications by designing Python services and APIs that enhance data processing capabilities in both cloud and on-premises settings, ensuring robust performance and seamles...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Technical Services

$90K - $130K *

Drive business growth by executing strategic sales plans and building client relationships. Leverage industry tools to identify prospects, present solutions, and negotiate contracts while collaboratin...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$115K - $150K *

Join a team that's dedicated to guiding recovery efforts post-disaster. Lead a multi-disciplinary team, leveraging your expertise in FEMA programs to support local governments through complex recovery...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Business Services

$222K - $288K *

Transform innovation in healthcare as a strategic leader driving early-stage technology initiatives, translating clinical needs into viable product concepts, and orchestrating cross-functional collabo...

United StatesRemote

Reposted 5 days ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $140K *

Drive organizational success by partnering with field leaders to align workforce strategies, enhance talent development, and manage workplace resolutions, ensuring effective staffing and engagement ac...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Technical Services

$90K - $105K *

Accelerate audit excellence by managing financial and operational audits, ensuring efficiency and compliance while fostering continuous improvement and collaboration across teams to deliver high-quali...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$210K - $256K *

Transform the landscape of data management by leading a multi-year program that integrates governance, risk, and stakeholder alignment across diverse workstreams in a regulated banking environment, en...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Information Technology

$210K - $273K *

Drive the evolution of a robust online ML inference platform, enhancing model deployment, performance, and safety in high-traffic environments by collaborating with cross-functional teams and spearhea...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$83K - $103K *

Drive procurement excellence by managing purchase orders, vendor performance, and compliance. Collaborate across departments to enhance efficiency and sustainability in sourcing commercial goods and s...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$165K - $195K *

Join a dynamic privacy team to provide legal counsel on global privacy, cybersecurity, and AI governance. Leverage your expertise to translate complex legal requirements into actionable strategies, dr...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $170K *

Empower your career by leading media planning and client management. Drive strategic excellence, mentor teams, and enhance client relationships while navigating industry challenges and innovations to...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Media

$120K - $230K *

Join a team that's driving growth by identifying and closing new business opportunities in consulting and AI-led transformation. Leverage your sales expertise to build strategic partnerships and accel...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Information Technology

$149K - $223K *

Unlock potential by leading enterprise AI solutions, bridging sales and technical teams to deliver impactful transformations. Engage with customers to architect scalable solutions, ensuring operationa...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$62K - $107K *

Join a team that's dedicated to empowering students with autism through innovative, community-based programs. Support their transition to independence by implementing effective behavioral strategies a...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.