Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$132K - $302K *

Shape the future of financial services by designing enterprise-scale Data 360 and AI solutions. Lead architecture decisions, mentor teams, and drive innovation across Banking, Capital Markets, and Ins...

Today

  •   8 - 10 years exp.  •   Business Services

$90K - $100K *

Tackle new business growth as a key player in driving the sales cycle. Leverage your sales expertise to build relationships with enterprise clients, close deals, and expand market presence while worki...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Legal & Accounting

$92K - $110K *

Elevate your career by leading cross-functional production planning efforts, ensuring timely delivery commitments, optimizing capacity, and driving operational excellence across multiple sites in the...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Transform your career by leading a dynamic team in a 24/7 airport operations environment, ensuring seamless baggage handling and exceptional service delivery while driving continuous improvement and s...

Today

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Champion operational excellence by leading a dynamic team in a 24/7 airport environment, ensuring seamless baggage handling and stakeholder communication while driving continuous improvement and perfo...

Today

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Join a team that's dedicated to ensuring electrical systems meet high standards in airport construction projects. Oversee inspections, testing, and compliance while collaborating with engineers and co...

Today

  •   8 - 10 years exp.  •   Business Services

$79K - $141K *

Optimize leave administration processes by managing employee leave requests, ensuring compliance with regulations, and facilitating smooth transitions back to work. Collaborate with HR and legal teams...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Transportation

$175K - $195K *

Unlock potential by leading strategic M&A initiatives across Europe and APAC. Drive deal execution with autonomy, manage due diligence, and collaborate with senior leadership to shape investment strat...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$125K - $150K *

Inspire transformative growth by leading strategic advancement initiatives, enhancing philanthropic resources, and fostering impactful relationships to align with organizational goals and drive missio...

Today

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$162K - $170K *

Drive advanced machine learning solutions as a key contributor to our perception team, focusing on deep learning and computer vision to enhance robotics technology and bring innovative models from ide...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$130K - $170K *

Drive impactful credit risk analysis across the consumer lending lifecycle, enhancing underwriting strategies and loss mitigation efforts. Collaborate with cross-functional teams to leverage data and...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$250K - $300K *

Execute innovative strategies to acquire and expand client relationships, leveraging expertise in AI/ML solutions. Be a proactive networker, navigating complex sales cycles to foster business growth a...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$110K - $125K *

Transform complex scientific data into clear medical communications. Lead multiple projects in Oncology, guiding writers and ensuring high editorial standards while engaging with clients to support th...

Philadelphia, PARemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$110K - $125K *

Champion high-quality medical communications in Oncology by leading projects, guiding writers, and ensuring editorial excellence. Elevate client relations and drive successful outcomes while advancing...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$150K - $185K *

Unlock potential by driving innovative infrastructure solutions for scalable deployments, collaborating with customers to refine requirements, and enhancing operational efficiency through automation a...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$114K - $154K *

Drive operational excellence by leading manufacturing, warehouse, and maintenance teams. Optimize processes, enhance performance metrics, and foster a high-performing culture while ensuring compliance...

Reposted today

  •   5 - 7 years exp.  •   Staffing

$94K - $122K *

Transform operational excellence by leading cross-functional Continuous Improvement initiatives. Collaborate with teams to apply Lean and Six Sigma methodologies, driving measurable cost savings and e...

Reposted today

  •   5 - 7 years exp.  •   Transportation

$115K - $180K *

Create a high-impact events program to drive pipeline and revenue. Own strategy, execution, and results of senior-level engagements, ensuring strong alignment with enterprise sales and marketing objec...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Join a team that's focused on enhancing machine reliability and uptime. Drive innovative maintenance strategies, collaborate across departments, and utilize advanced technologies to optimize operation...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$84K - $118K *

Join a team that's dedicated to enhancing nuclear power safety and efficiency. As a Mid-Level Instrumentation and Controls Engineer, you'll collaborate on innovative projects, mentor junior engineers...

Reposted today

  •   Less than 5 years exp.  •   Real Estate & Construction

$160K - $165K *

Join a team that's dedicated to enhancing cloud security for critical operations. Leverage your expertise to identify vulnerabilities, respond to incidents, and implement robust security measures in c...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$145K - $169K *

Transform business outcomes by leading franchise operations, driving growth, and executing strategic plans across diverse markets. Collaborate with teams to enhance performance and ensure alignment wi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Food & Beverages

$79K - $100K *

Shape your career by designing fire alarm systems for commercial projects. Lead design teams, ensure code compliance, and collaborate with project managers to deliver high-quality solutions while ment...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$174K - $204K *

Drive transformative growth by leading strategic initiatives that redefine operational models and enhance market performance across franchise systems. Collaborate with cross-functional teams to ensure...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Food & Beverages

$91K - $110K *

The Account Executive in-territory for Justworks is responsible for managing the full sales cycle, including prospecting, building relationships, and closing deals within the Orange County area. This...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.