Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$89K - $148K *

Optimize clinical documentation integrity operations by leading a dedicated team, ensuring compliance with best practices, and enhancing performance metrics to support effective healthcare delivery an...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Business Services

$113K - $188K *

Optimize program execution by leading Integrated Master Scheduling (IMS) for Department of War initiatives. Collaborate with stakeholders to enhance visibility, manage risks, and support decision-maki...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Business Services

$98K - $163K *

Analyze and maintain program data to enhance recruitment and onboarding processes. Collaborate with stakeholders to ensure accurate reporting and insights that drive decision-making and improve partic...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Business Services

$89K - $148K *

Lead the charge in enhancing financial operations by delivering advanced analysis, ensuring compliance, and supporting internal controls for federal financial systems, contributing to a high-performin...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Business Services

$149K - $248K *

Shape the future of Navy readiness by leading advanced analytics and AI initiatives. Drive predictive modeling and machine learning solutions to optimize supply chains and enhance operational readines...

4 days ago

  •   5 - 7 years exp.  •   Business Services

$90K - $145K *

Drive the development and management of third-party vendor relationships, ensuring effective communication, oversight, and resource allocation within the Vendor Management team to meet corporate objec...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$93K - $105K *

Shape the future of mental health services by overseeing psychological assessments and treatments within correctional facilities, collaborating with multidisciplinary teams to enhance inmate care and...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$75K - $110K *

Champion Windows administration by providing expert support for our laptop fleet. Own imaging, deployment, and troubleshooting while ensuring seamless user experiences. Collaborate with teams to enhan...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $165K *

Oversee full lifecycle of U.S. government programs, managing stakeholders and technical details to ensure timely delivery and compliance. Forge trust with clients while leading multiple complex projec...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$100K - $300K *

The Deep Learning Engineer will develop and refine models for robotic manipulation, designing, training, and deploying algorithms that enable robots to interact intelligently with their environments...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$141K - $166K *

Lead the charge in shaping product messaging and go-to-market strategies, driving awareness and adoption through cross-functional collaboration and strategic insights. This role demands a proactive in...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$162K - $271K *

Elevate your career by leading global Business Continuity Management initiatives. Collaborate with senior leaders to enhance organizational resilience, implement effective strategies, and ensure prepa...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$124K - $207K *

Drive impactful analytics in Medical Affairs by developing KPIs, analyzing data trends, and collaborating with cross-functional teams to enhance decision-making and resource allocation for optimal bus...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$254K - $423K *

Champion the Rhu/GI portfolio strategy, driving growth and performance across brands. Lead a dynamic team, optimize patient impact, and collaborate cross-functionally to enhance market presence and ac...

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Help us enhance safety and health standards by managing EHS programs, ensuring compliance, and leading a dedicated team to improve guest and employee care through proactive strategies and effective tr...

4 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$80K - $95K *

Lead the charge in optimizing laboratory operations, ensuring compliance, and driving performance in a high-throughput environment while managing a large team and delivering exceptional analytical ser...

4 days ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Lead the charge in optimizing laboratory operations, ensuring compliance, and driving performance excellence. Manage a large team while delivering high-quality analytical services in a fast-paced envi...

4 days ago

  •   5 - 7 years exp.  •   Business Services

$104K - $122K *

Join a team that's dedicated to delivering exceptional patient care through innovative technology and personalized treatment plans, while enjoying a supportive environment that fosters professional gr...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

$212K - $318K *

Lead the charge in shaping global payer evidence strategies for pipeline assets, ensuring integration of health economic models and real-world data into clinical trials. Collaborate cross-functionally...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$212K - $318K *

Lead the charge in shaping global payer evidence strategies for neurology assets. Drive value maximization, access expansion, and evidence generation across product lifecycles, collaborating with cros...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$71K - $96K *

Advance trade compliance by supporting customs activities, ensuring accurate import processes, and maintaining regulatory standards. Collaborate with teams to enhance operational integrity and drive e...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$175K - $195K *

Shape the future of global HR operations by enhancing systems and processes for a seamless employee lifecycle. Collaborate cross-functionally to improve workflows, compliance, and service effectivenes...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $187K *

Grow your career with a dynamic team focused on crafting scalable software solutions. Collaborate cross-functionally to design impactful APIs and lead innovations that drive efficiency and elevate cus...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$156K - $234K *

Drive the evolution of Sales Operations into an AI-driven powerhouse by architecting innovative AI solutions, redesigning processes, and establishing best practices that enhance efficiency and perform...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$320K - $400K *

Join a leading team of Cardiothoracic Surgeons enhancing patient outcomes through innovative techniques and collaborative care. Experience diverse cases in a supportive environment, utilizing advanced...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.