Find Your Next High-Paying Job in Pennsylvania

Are you a professional seeking $100K+ jobs in Pennsylvania? You've come to the right place. Ladders is your hub for high-paying Pennsylvania jobs across a broad range of industries, including Tech, Finance, Healthcare, and more.

Unlock Opportunities in Pennsylvania

Pennsylvania, known for its rich history and diverse job market, offers a plethora if opportunities for ambitious professionals seeking high-paying jobs.

How Ladders Can Help

Whether you're looking for jobs in Philadelphia, Pittsburgh, or smaller cities within Pennsylvania, Ladders has got you covered. Our selection of $100K+ jobs in Pennsylvania is carefully curated and regularly updated. Start your job searc on Ladders today!

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $120,923

Sort By: Relevance

$137K - $235K *

Lead the charge in developing robust biomarker strategies for clinical programs, collaborating with cross-functional teams to ensure compliance with objectives and high-quality data integration, essen...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Redefine pharmaceutical care by ensuring safe and effective medication therapies, monitoring patient outcomes, and advising medical teams to enhance healthcare quality and efficiency...

Today

  •   5 - 7 years exp.  •   Healthcare

$74K - $130K *

Drive impactful regional infrastructure projects by collaborating with a skilled team. Engage in roadway design, technical document preparation, and multi-disciplinary project support, contributing to...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Transportation

$90K - $120K *

Unlock innovation as a Senior Engineer, leading technical design efforts and ensuring project success through quality assurance and collaboration, while managing timelines and budgets effectively acro...

Today

  •   11 - 15 years exp.  •   Real Estate & Construction

$90K - $130K *

Contribute to strategic evaluations of gaming portfolios, analyzing trends and opportunities while supporting investment recommendations. Collaborate with cross-functional teams to balance performance...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $150K *

Join a team that's focused on growing client relationships and driving profitable expansion. Lead day-to-day operations, collaborate across service lines, and enhance client satisfaction while managin...

Reposted today

  •   11 - 15 years exp.  •   Healthcare

$95K - $105K *

Champion a data-driven culture by managing Talent data systems, producing reports, and collaborating across teams to enhance HR practices and empower staff with actionable insights and resources for i...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $130K *

Lead cross-functional teams to develop innovative fintech products, ensuring timely delivery and enhancing user experiences. Collaborate with diverse stakeholders to align business needs with technolo...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $163K *

Unlock potential by building AI-driven music production features end-to-end. Join a dynamic team to shape audio ML experiences that empower creators, ensuring quality while moving quickly from concept...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

$79K - $124K *

Transform healthcare by becoming a Cardiovascular Disease Specialist, where you'll leverage scientific expertise and collaborate with local teams to deliver impactful, patient-focused solutions across...

Today

  •   Less than 5 years exp.  •   Healthcare

$140K - $170K *

Transform operational excellence across multiple dental practices while developing high-performing teams and enhancing patient experiences. Drive strategic initiatives that align with organizational g...

Today

  •   5 - 7 years exp.  •   Healthcare

$104K - $157K *

Champion optimization of line haul strategies to enhance network efficiency, collaborating across teams to ensure timely operations and execution of plans for quality load management and resource util...

Today

  •   5 - 7 years exp.  •   Transportation

$120K - $150K *

Unlock enterprise-level leadership by driving digital modernization strategies. Collaborate with executives to design future-state architectures and implement governance measures that ensure organizat...

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$79K - $124K *

Manage sourcing operations for pharmacokinetics outsourcing. Partner with teams to execute workflows, ensure compliance, maintain records, and support financial tracking. Contribute to process improve...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $205K *

Contribute to diverse business lines by providing legal counsel on asset management, compliance, and SEC regulations. Utilize your experience in dispute resolution and strategic thinking to navigate c...

Today

  •   11 - 15 years exp.  •   Legal & Accounting

$86K - $138K *

Transform processes at the intersection of technology and security by developing and managing Identity and Access Management (IAM) solutions, ensuring system integrity and user access control across v...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$130K - $160K *

Lead enterprise architecture initiatives, integrating digital modernization and strategic goals across multidisciplinary teams. Collaborate with executives to enhance organizational performance and dr...

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $150K *

Lead the charge in shaping enterprise architecture strategies that align with long-term goals, fostering collaboration across multidisciplinary teams to innovate digital modernization and enhance oper...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$85K - $95K *

Accelerate progress at managing project scope, deliverables, and outcomes. Lead cross-functional teams to achieve project milestones on time and within budget while ensuring alignment with enterprise...

Today

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Lead the charge in transforming enterprise architecture by spearheading strategic initiatives, fostering collaboration across multidisciplinary teams, and delivering comprehensive modernization roadma...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$93K - $155K *

Empower your career by analyzing healthcare data to drive insights for specialty pharmacy operations, ensuring performance and efficiency for client programs through robust analytics and reporting str...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Help us deliver innovative enterprise architecture leadership to align business strategies with digital modernization efforts, enhancing organizational performance and governance in a dynamic, cross-f...

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$78K - $95K *

Elevate patient care by developing personalized therapy plans, delivering exceptional rehabilitation services, and fostering collaborative relationships in a supportive environment focused on professi...

Today

  •   Less than 5 years exp.  •   Healthcare

$133K - $173K *

Drive cybersecurity excellence by leading threat detection and incident response teams. Champion cross-functional collaboration to enhance security operations, ensuring readiness against cyber threats...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$95K - $140K *

Optimize healthcare technology by architecting scalable back-end services. Collaborate across teams to ensure systems adhere to regulatory standards while delivering high performance and reliability i...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What industries in Pennsylvania offer the most $100K+ jobs?question toggle

    There are numerous industries in Pennsylvania offering $100K+ jobs, including Tech, Finance, Healthcare, and more.

  • Can I find $100K+ jobs all over Pennsylvania on Ladders?question toggle

    Yes, Ladders list high-paying jobs in all areas of Pennsylvania including in big cities like Philadelphia and Pittsburgh, as well as smaller cities.

  • How often are the $100K+ job listings in Pennsylvania updated on Ladders?question toggle

    The $100K+ job listings in Pennsylvania are updated regularly to ensure that our users have access to the most current opportunities.