Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$150K - $180K *

Transform the commercial landscape by building a scalable sales engine, driving strategic deals, and leading with innovation in a dynamic life sciences environment. Collaborate closely with leadership...

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$92K - $156K *

Join a team that's driving operational excellence in accounting across North America. Lead end-to-end accounting processes, enhance reporting accuracy, and foster collaboration while managing a dynami...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Grow your career by owning enterprise sales processes, building relationships, and closing deals in home décor, beauty/wellness, and online retail. Drive significant revenue growth by leveraging consu...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $211K *

Unlock strategic growth opportunities by collaborating with leadership to shape TE's competitive landscape and drive impactful business initiatives across global markets...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$145K - $181K *

Develop innovative power solutions for AI data centers, collaborating with cross-functional teams to drive product development from concept to launch, ensuring alignment with customer needs and market...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Lead the charge in shaping consumer insights and category strategies for a plant-forward portfolio. Drive data-driven decisions, manage vendor relationships, and build a customer-centric insights func...

Today

  •   8 - 10 years exp.  •   Food & Beverages

$70K - $105K *

Optimize partnerships with leading technology vendors to drive revenue growth and market presence. Collaborate cross-functionally to align strategies and co-sell initiatives, while effectively managin...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Media

$112K - $135K *

Join a team that's passionate about crafting enterprise-scale applications. Leverage your advanced Java and Spring Boot expertise to drive innovative solutions while collaborating cross-functionally i...

Reposted today

  •   8 - 10 years exp.  •   Staffing

$80K - $95K *

Elevate your career by joining a dynamic cybersecurity team focused on enterprise security operations, risk management, and compliance initiatives. Leverage your expertise in Splunk and SIEM technolog...

Reposted today

  •   Less than 5 years exp.  •   Staffing

$190K - $220K *

Shape the future of product design by leading a dynamic team, setting vision, and enhancing user experiences across platforms while driving design excellence and mentoring talent...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Transform regional account management by driving sales strategies and fostering relationships with key stakeholders. Leverage insights to enhance execution and programming, ensuring alignment with bra...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$80K - $95K *

Lead the charge in driving retail growth across the Northeast by executing strategic sales initiatives, enhancing customer relationships, and leveraging data insights to expand market share in the com...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Lead the Materials Science & Applications Division, driving innovative research and development in advanced manufacturing technologies to enhance military capabilities and foster collaboration with ke...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Champion advanced manufacturing technologies to enhance military capabilities. Collaborate with teams to develop innovative materials and processes, ensuring alignment with organizational objectives a...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$173K - $254K *

Shape the future of clean energy by advocating for impactful policies and regulations. Collaborate with stakeholders to drive market growth and protect existing opportunities in the solar and storage...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Energy & Utilities

$130K - $135K *

Partner with us to drive strategic initiatives across Support Services and data centers. This role ensures effective project management, governance, and measurable outcomes in a dynamic environment, f...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Engage with customers to deliver technical support and solutions in solar applications. Leverage your expertise to enhance system performance, provide training, and ensure customer satisfaction while...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$92K - $148K *

Lead the design and development of innovative biomedical solutions, guiding cross-functional teams through the product life-cycle. Collaborate with healthcare professionals to ensure product efficacy...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$189K - $199K *

Join a team that's redefining consumer relationships with food through innovative research. Drive impactful strategies and insights in a collaborative environment focused on behavior change and enhanc...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$100K - $120K *

Champion project success by leading diverse teams and driving innovative strategies. Deliver exceptional results through structured execution, ensuring clear communication and collaboration across all...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Join a team that's dedicated to optimizing database performance and security. You'll manage routine operations, troubleshoot issues, and implement design changes, ensuring reliable database functional...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$180K - $190K *

Drive impactful growth of our subscription program by shaping market strategies, enhancing member engagement, and leveraging user insights to position offerings that attract and retain loyal customers...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$88K - $105K *

Shape the future of healthcare revenue management by leading IDR processes, ensuring compliance, and driving data-informed improvements while mentoring a team of analysts to optimize workflows and enh...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$207K - $218K *

Champion innovative machine learning solutions to enhance service availability, optimize routing, and improve fulfillment efficiency in a complex logistics environment, driving profitability and shopp...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Consumer Technology

$299K - $343K *

Advance your career with a leading academic medical center offering a flexible outpatient-focused schedule, teaching opportunities, and a supportive environment for clinical growth and research partic...

Today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.