Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$120K - $145K *

Drive the evolution of LNG technical frameworks, ensuring alignment across engineering, commercial, and supplier teams. Enhance project execution and customer contracts while maintaining clarity and c...

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$250K - $250K+*

Support research initiatives by engaging in human subject activities, data collection, and regulatory submissions. Collaborate with study teams to enhance clinical research efforts and develop essenti...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Deliver impactful project management by co-managing resources, schedules, and risks. Ensure compliance and alignment with strategic goals while utilizing reporting tools to track performance and drive...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$118K - $178K *

Join a team that's driving growth through consultative sales in clinical research. Collaborate with pharmaceutical and biotech leaders to enhance global health by advancing life-changing therapies thr...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Help us modernize complex legacy applications by designing, developing, and implementing scalable solutions. Collaborate with cross-functional teams to enhance system performance, security, and reliab...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Oversee a team of Field Automation Technicians, ensuring the installation, maintenance, and troubleshooting of automated systems meet operational and safety standards across various locations...

3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$78K - $119K *

Lead the charge in managing operations for a state agency, overseeing procurement, facilities, and safety programs. Drive team performance and ensure compliance across multiple locations while support...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$101K - $169K *

Optimize North American sales processes and systems to enhance efficiency, drive adoption, and improve outcomes. Collaborate with teams to identify issues, implement solutions, and ensure consistent u...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Transportation

$80K - $95K *

Grow your career by enhancing manufacturing processes while ensuring quality and safety. Drive continuous improvement in production efficiency and lead training initiatives to empower team members at...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$69K - $104K *

Shape the future of environmental protection by managing air emission testing activities, evaluating scientific data, and ensuring compliance with regulations. Collaborate with stakeholders to enhance...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$89K - $111K *

Join us to provide essential nursing care for offenders, ensuring safe health operations. You'll conduct assessments, administer treatments, and educate individuals, contributing to a stable environme...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$92K - $110K *

Transform patient care by collaborating with physicians to assess and plan effective treatment strategies. Leverage your nursing expertise to enhance clinical outcomes and support a dynamic healthcare...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $220K *

Pioneer innovative sales strategies as you engage with clients, guiding them through the QuotaPath platform. Leverage AI tools to enhance efficiency and influence product development while driving new...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $195K *

Contribute to the success of IVD and CDx programs by leading cross-functional teams through development, validation, and submission processes. Drive strategic execution and ensure alignment with regul...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$184K - $356K *

Join a team that's pushing the boundaries of AI technology. As a Deep Learning Engineer, you'll integrate advanced CUDA features and optimize frameworks for high-performance AI applications, tackling...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$90K - $192K *

Empower a dynamic recruiting team to attract top pharmacy talent, develop strategic hiring initiatives, and enhance workforce solutions. Collaborate with business leaders to address evolving needs and...

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$90K - $105K *

Empower your career by leading clinical services in invasive cardiology. Oversee patient care, staff training, and quality control while ensuring compliance with policies and enhancing patient outcome...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$86K - $173K *

Unlock potential by driving growth in a dynamic sales environment, engaging with diverse stakeholders to close new business and expand existing accounts in the healthcare sector. Embrace a remote role...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Drive logistics optimization and cost reduction initiatives across global service operations, enhancing efficiency and performance in transportation and network design while collaborating with cross-f...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$188K - $245K *

Drive the vision for a unified longitudinal patient record, ensuring data accuracy and completeness across multiple sources. Collaborate with cross-functional teams to enhance clinical data utility an...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in strategic facilities management, overseeing operations, maintenance, and capital projects to enhance safety, efficiency, and sustainability while developing a skilled team to meet f...

3 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $130K *

Elevate your career by leading a dynamic engineering section, managing project scope, budget, and quality. Drive team development, strategic planning, and client satisfaction while ensuring high-quali...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$135K - $160K *

Transform the future of AI by designing cutting-edge datasets and benchmarks. Collaborate with partners and cross-functional teams to drive impactful research and commercial strategies, enhancing mode...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$108K - $130K *

Join a team that's dedicated to leading engineering excellence by managing project tasks, budgets, and staff development while ensuring high-quality service delivery and client satisfaction across mul...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$108K - $130K *

Develop your leadership skills by managing a technical discipline section, overseeing project delivery, budget management, and staff development while ensuring high-quality service and client satisfac...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.