Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
Average Salary: $122,521
Senior Director TA Portfolio Delivery Lead
$170K - $200K *
Champion strategic oversight of global R&D Program Management, driving agile project delivery and cross-functional alignment. Lead a diverse team to enhance portfolio operations and ensure successful...
2 days ago
$146K - $173K *
Elevate your career by joining a dynamic clinical development team, contributing to protocol development and study delivery while ensuring compliance and quality in clinical research initiatives...
2 days ago
Clinical Pharmacy Manager - Mount Carmel East
$110K - $130K *
Advance clinical pharmacy services by leading initiatives that enhance medication therapy, improve patient outcomes, and foster collaboration among healthcare teams. Drive quality improvement and supp...
2 days ago
Environmental Health & Safety Manager
$85K - $100K *
Drive safety initiatives and compliance programs, ensuring a secure and efficient work environment. Oversee hazardous waste management, regulatory reporting, and facility improvements while leading ac...
Reposted 2 days ago
Senior Manager, Medical Affairs (MSL)
$160K - $220K *
Join a dynamic team as a scientific expert, driving engagement and advancing medical strategy in respiratory health. Collaborate with healthcare professionals to shape innovative therapies and improve...
2 days ago
Information System Security Officer (ISSO)
$90K - $189K *
Lead cybersecurity initiatives as an Information System Security Officer, ensuring compliance and robust security controls for critical information systems while collaborating with stakeholders to saf...
Reposted 2 days ago
Oracle Fusion SCM Inventory Architect
$90K - $189K *
Join a team that's transforming supply chain operations through Oracle Fusion SCM. Lead the design and configuration of inventory solutions, ensuring real-time visibility and accountability for critic...
2 days ago
$63K - $129K *
Unlock potential by providing advanced support for Momentum Financials, collaborating with stakeholders to resolve issues, and enhancing system functionality in a dynamic environment. Bring your analy...
2 days ago
Systems Engineer - Data & Automation
$75K - $158K *
Innovate solutions by leveraging your expertise in data automation and systems engineering to enhance operational efficiency and support enterprise financial management systems...
2 days ago
$75K - $158K *
Champion quality assurance by collaborating in Agile teams to deliver robust software solutions. Leverage your testing expertise to enhance product quality and drive continuous improvement in a dynami...
2 days ago
Acquisition SME/ Business Systems Analyst
$75K - $158K *
Elevate your career by leveraging your expertise in business analysis to enhance Momentum Financials and Acquisitions. Collaborate with stakeholders to drive process improvements and ensure effective...
2 days ago
CCARS / Document Management Software Test Engineer
$75K - $158K *
Champion the testing of enterprise content management systems, ensuring seamless integration with SAP. Collaborate with cross-functional teams to validate workflows, enhance quality assurance, and dri...
2 days ago
Senior Partner Marketing Manager
$110K - $130K *
Empower partner marketing initiatives by developing strategies that drive qualified referrals and pipeline growth across diverse partner ecosystems in North America and EMEA. Collaborate with stakehol...
2 days ago
$85K - $100K *
Lead the charge in overseeing early phase clinical trials, providing statistical expertise and ensuring compliance with regulatory standards while collaborating with clients and stakeholders to delive...
2 days ago
$210K - $250K *
Lead the charge in advancing medical initiatives, providing strategic guidance and expert consultation in cardiology, while ensuring compliance and operational excellence across project teams and medi...
Reposted 2 days ago
$100K - $120K *
Lead the charge in project management, coordinating cross-functional teams to deliver high-quality results on time and within budget while fostering stakeholder engagement and team development...
Reposted 2 days ago
$100K - $120K *
Execute clinical trial management activities, ensuring quality outcomes and compliance. Collaborate with cross-functional teams, manage timelines and budgets, and build strong relationships with stake...
2 days ago
Transportation Supervisor - Class A required
$89K - $149K *
Join a dynamic team as a Transportation Supervisor, leading night-shift operations. Oversee freight movement, ensure safety compliance, and develop drivers while fostering a positive culture in a larg...
2 days ago
Senior Analyst, Business Operations & Strategy
$111K - $167K *
Optimize the customer journey by leveraging analytics and strategic insights to enhance pipeline generation, forecasting, and sales enablement for a growing Property Care business. Collaborate cross-f...
2 days ago
$133K - $200K *
Transform your career by leading regulatory compliance for Medicaid and Medicare in the U.S. Dental Business Unit. Collaborate with cross-functional teams to enhance compliance controls and drive oper...
2 days ago
$95K - $115K *
Lead the charge in driving sales growth and operational excellence across multiple locations. Manage a high-performing team, implement strategies, and foster customer relationships to achieve revenue...
2 days ago
$69K - $100K *
Inspire excellence in coding operations by leading a dedicated team, ensuring compliance, accuracy, and timely billing. Collaborate with stakeholders to enhance documentation quality and coding integr...
2 days ago
$70K - $205K *
Join a team that's redefining digital forensics by leveraging AI to enhance investigations, develop innovative tools, and engage with clients. Your expertise will drive defensible decisions and stream...
Reposted 2 days ago
Software Product Management Pre Sales Assoc. Director - Health & Human Services Software
$163K - $369K *
Lead the charge in complex software sales cycles, bridging product expertise with client needs. Engage in pre-sales activities, develop solution narratives, and enable partners to drive enterprise dea...
Reposted 2 days ago
Software Product Management Pre Sales Senior Manager- Pre Sales - Manufacturing Software
$132K - $271K *
Lead pre-sales efforts by delivering tailored product demos, supporting complex sales cycles, and collaborating with clients and partners to drive solution success and accelerate pipeline conversion...
Reposted 2 days ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.