Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$104K - $122K *

Join a team that's dedicated to delivering exceptional patient care through innovative technology and personalized treatment plans, while enjoying a supportive environment that fosters professional gr...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$212K - $318K *

Lead the charge in shaping global payer evidence strategies for pipeline assets, ensuring integration of health economic models and real-world data into clinical trials. Collaborate cross-functionally...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$212K - $318K *

Lead the charge in shaping global payer evidence strategies for neurology assets. Drive value maximization, access expansion, and evidence generation across product lifecycles, collaborating with cros...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$71K - $96K *

Advance trade compliance by supporting customs activities, ensuring accurate import processes, and maintaining regulatory standards. Collaborate with teams to enhance operational integrity and drive e...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$175K - $195K *

Shape the future of global HR operations by enhancing systems and processes for a seamless employee lifecycle. Collaborate cross-functionally to improve workflows, compliance, and service effectivenes...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $187K *

Grow your career with a dynamic team focused on crafting scalable software solutions. Collaborate cross-functionally to design impactful APIs and lead innovations that drive efficiency and elevate cus...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$156K - $234K *

Drive the evolution of Sales Operations into an AI-driven powerhouse by architecting innovative AI solutions, redesigning processes, and establishing best practices that enhance efficiency and perform...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$320K - $400K *

Join a leading team of Cardiothoracic Surgeons enhancing patient outcomes through innovative techniques and collaborative care. Experience diverse cases in a supportive environment, utilizing advanced...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$500K+*

IntelliRad Imaging, LLC is seeking a Remote Diagnostic Radiologist to join their physician-owned group, working evening shifts from 8 PM to 4 AM EST. The role involves interpreting general radiology s...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$94K - $110K *

Join a team that's driving impactful decisions by leveraging your expertise in risk assessment and underwriting. Collaborate with producers, train emerging talent, and contribute to marketing efforts...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$88K - $105K *

Champion compliance excellence by leading SOX initiatives, enhancing controls, and collaborating with stakeholders to elevate financial reporting integrity while driving audit projects from planning t...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$94K - $266K *

Drive growth by managing the full sales cycle for software products, engaging clients consultatively, and collaborating across teams to close complex deals and achieve measurable business outcomes...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$132K - $271K *

Unlock potential by leading pre-sales efforts for complex software solutions. Collaborate with clients and partners to deliver tailored demonstrations, support RFPs, and develop reusable assets that d...

2 days ago

  •   8 - 10 years exp.  •   Business Services

$125K - $150K *

Empower future clinicians by delivering high-quality education and patient care in rheumatology, fostering a collaborative environment focused on treating diverse rheumatic diseases while maintaining...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$180K - $220K *

Transform the field of Geriatrics by delivering exceptional clinical care, mentoring medical professionals, and driving educational initiatives within a leading academic environment. Engage in direct...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$132K - $271K *

Support complex software sales cycles by delivering tailored demos, responding to client needs, and developing reusable pre-sales assets. Collaborate with stakeholders to drive pipeline conversion and...

2 days ago

  •   8 - 10 years exp.  •   Business Services

$94K - $266K *

Empower growth by driving software sales through consultative client engagement, managing the full sales cycle, and collaborating across teams to close complex deals that deliver measurable business o...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$135K - $160K *

Deliver impactful AI strategies while leading diverse teams and collaborating with executives. Drive client growth and innovation by leveraging your expertise in life sciences and technology transform...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Business Services

$87K - $293K *

Lead client transformation initiatives at the intersection of strategy, technology, and operations. Empower teams to deliver AI-driven solutions and reshape banking practices while ensuring alignment...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Business Services

$84K - $135K *

Grow your career by delivering tailored energy solutions to commercial clients. Utilize your sales expertise in the deregulated market while cultivating long-term partnerships and engaging with divers...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$87K - $293K *

Transform client experiences by leading strategic banking engagements that merge business strategy, technology solutions, and operational excellence to deliver innovative AI-powered outcomes and foste...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Business Services

$120K *

Lead the charge in empowering marketing agencies to integrate affiliate and creator marketing services. Develop comprehensive training and certification programs to enhance agency capabilities and dri...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $150K *

Shape the future of cybersecurity by identifying vulnerabilities in blockchain smart contracts. Collaborate on security audits, enhance tools, and embrace emerging technologies to bolster security sol...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$73K - $110K *

Elevate your career by ensuring coding accuracy and compliance in a dynamic healthcare environment. Collaborate with teams to enhance documentation quality and drive improvements in coding practices w...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $130K *

Manage Oracle PPM implementations from strategy to deployment, driving efficiency and fostering collaboration among teams while mentoring junior staff and ensuring alignment with transformation object...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.