Find Your Next High-Paying Job in Pennsylvania

Are you a professional seeking $100K+ jobs in Pennsylvania? You've come to the right place. Ladders is your hub for high-paying Pennsylvania jobs across a broad range of industries, including Tech, Finance, Healthcare, and more.

Unlock Opportunities in Pennsylvania

Pennsylvania, known for its rich history and diverse job market, offers a plethora if opportunities for ambitious professionals seeking high-paying jobs.

How Ladders Can Help

Whether you're looking for jobs in Philadelphia, Pittsburgh, or smaller cities within Pennsylvania, Ladders has got you covered. Our selection of $100K+ jobs in Pennsylvania is carefully curated and regularly updated. Start your job searc on Ladders today!

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $120,966

Sort By: Relevance

$162K - $271K *

Shape the future of user experience in medical AI platforms, owning design and integration of AI workflows. Partner with engineering and business teams to enhance usability, trust, and adoption across...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$106K - $176K *

Drive information protection strategy by leading cybersecurity compliance and data privacy programs, collaborating with multidisciplinary teams to secure sensitive data within a regulated environment...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $250K *

Drive growth by partnering with primary care providers to enhance patient access. Engage strategically with healthcare teams, delivering targeted education and sales support to elevate business perfor...

US-AnywhereRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$183K - $238K *

Drive operational excellence in renewable energy through strategic leadership, ensuring safe, cost-effective management of diverse energy assets across a regional portfolio while fostering collaborati...

3 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$90K - $100K *

Join a team that assesses loss control for commercial auto accounts across multiple states, delivering comprehensive audits and reports while managing complex schedules and communications to enhance s...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$102K - $153K *

Join a team that's dedicated to optimizing a complex, 24/7 SAP environment. You'll ensure system uptime, drive performance improvements, and support business operations through innovative solutions an...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $145K *

Lead the charge in driving strategic marketing initiatives for Skin Health, leveraging cross-functional collaboration to optimize product performance and profitability while addressing the dynamic nee...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Shape the product strategy and lifecycle, collaborating with teams to define requirements and deliver user-focused features. Drive customer and market insights, prioritize backlog, and ensure product...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$182K - $240K *

Transform the landscape of Medical Affairs by designing innovative training programs that empower teams, elevate patient care, and drive excellence in a dynamic, cross-functional environment. Collabor...

US-AnywhereRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$113K - $211K *

Join a team that's shaping the future of Workday solutions by driving sales growth and building strong partnerships. Engage with C-level executives, lead complex sales processes, and develop innovativ...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$78K - $117K *

Optimize core network infrastructure lifecycle management by developing and supporting automation solutions. Collaborate with cross-functional teams to enhance network reliability and operational effi...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$138K - $165K *

Empower innovative software solutions by leading the vCMTS platform development. Drive strategic software initiatives and enhance system architecture while ensuring robust performance and quality, col...

3 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$150K - $180K *

Leverage your expertise to drive integrated technical delivery plans across mobile/wireless projects. Collaborate with cross-functional teams to ensure alignment, manage risks, and deliver impactful o...

3 days ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$88K - $105K *

Drive proactive labor relations strategies, ensuring compliance and positive engagement with unions. Support grievance resolutions while aligning organizational goals with long-term operational planni...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$250K - $384K *

Champion the safety strategy for SAE Level 3-4 Automated Driving Systems, leading the technical team and collaborating across departments to validate and ensure launch readiness of innovative and safe...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Transportation

$296K - $453K *

Drive innovation in AI deployment by leading model performance strategy, optimizing autonomous driving systems, and managing diverse teams to enhance inference quality. Shape technical direction while...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$134K - $207K *

Empower growth by leading strategic account management initiatives with Defense Primes and government customers. Drive business development through effective program management and cross-functional le...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$105K - $140K *

Execute comprehensive contract management for defense programs, ensuring compliance with regulations. Collaborate with internal and external stakeholders, leveraging expertise in government contracts...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$150K - $250K + excellent benefits package *

The Commissioner is a key member of the City's executive leadership, reports to the Chief Administrative Officer, and advises the Mayor's office on labor strategy, policy development, and emerging emp...

3 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$96K - $118K *

Unlock potential by leading engineering initiatives for high-speed machinery, driving improvements in safety, reliability, and performance. Collaborate with teams to solve complex technical issues and...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$112K - $154K *

Join a team that's redefining sales training excellence by crafting impactful educational experiences for sales professionals. Collaborate across departments to enhance learner capabilities and drive...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $158K *

Partner with us to enhance cybersecurity measures that protect critical Navy and Marine Corps systems. Engage with diverse teams, safeguard information, and ensure compliance in a hybrid work environm...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $210K *

Shape and lead SAP S/4HANA solutions for defense and security transformation. Collaborate with diverse teams to streamline processes, ensure quality, and implement best practices. Drive innovation wit...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$82K - $172K *

Join a team that's dedicated to implementing quality standards on Army programs, ensuring high-performance systems meet user requirements. Lead initiatives from development through implementation, man...

US-AnywhereRemote

3 days ago

  •   15+ years exp.  •   Aerospace & Defense

$68K - $143K *

Join a team that enhances accessibility by ensuring Section 508 compliance for DHS CISA documents. You will conduct testing and work collaboratively to create compliant content that meets federal stan...

US-AnywhereRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What industries in Pennsylvania offer the most $100K+ jobs?question toggle

    There are numerous industries in Pennsylvania offering $100K+ jobs, including Tech, Finance, Healthcare, and more.

  • Can I find $100K+ jobs all over Pennsylvania on Ladders?question toggle

    Yes, Ladders list high-paying jobs in all areas of Pennsylvania including in big cities like Philadelphia and Pittsburgh, as well as smaller cities.

  • How often are the $100K+ job listings in Pennsylvania updated on Ladders?question toggle

    The $100K+ job listings in Pennsylvania are updated regularly to ensure that our users have access to the most current opportunities.