Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$137K - $235K *

Lead the charge in safety analysis for innovative products, ensuring compliance and guiding strategic safety decisions. Collaborate with cross-functional teams to deliver high-quality evaluations and...

Reposted 3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$101K - $140K *

Drive the evolution of Business Systems by integrating automation and AI into our go-to-market processes. Collaborate with cross-functional teams to build scalable systems that enhance efficiency and...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$83K - $116K *

Unlock seamless financial operations by supporting API integrations and automation. Collaborate with finance teams to enhance data reliability and streamline workflows, ensuring efficient communicatio...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K *

Transform the future of retail by leading a dynamic team of store managers. Oversee multiple locations, drive operational excellence, and foster a positive work environment while ensuring exceptional...

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$115K - $145K *

Optimize security and IT operations, supporting diverse teams and managing requests while ensuring efficient access control and incident responses. Collaborate in a remote-first environment dedicated...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$60K - $99K *

Engage in the design and delivery of impactful learning experiences for service and sales teams, focusing on K-8 math products. Collaborate cross-functionally to ensure readiness and maintain high-qua...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Drive product strategy and execution for ConnectWise platforms, collaborating with cross-functional teams to enhance development, analyze market trends, and ensure effective solutions that align with...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Accelerate operational excellence by leading day-to-day clinical and administrative functions across multiple service lines, ensuring compliance and enhancing patient experiences while driving strateg...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$275K - $325K *

Join a team that's redefining financing products through innovative engineering. Lead complex initiatives, modernize systems, and leverage AI tools to enhance software development while ensuring data...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$60K - $112K *

Transform student outcomes by leading innovative math instruction that inspires a passion for numbers. Collaborate with educators to implement engaging curricula and foster an inclusive learning envir...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$195K - $391K *

Drive growth by identifying and developing new business opportunities in genomics workflows. Engage with researchers and decision-makers to expand market presence and accelerate customer adoption of i...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$199K - $235K *

Lead the charge in building robust backend services that streamline customer onboarding and provisioning workflows, ensuring seamless activation and reliable integrations across teams for optimal user...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $181K *

Transform customer experiences by driving product strategy and execution. Collaborate across teams to leverage data and AI, ensuring alignment on outcomes while navigating ambiguity and prioritizing h...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $130K *

Lead the charge in designing and optimizing large-scale data warehousing systems, enhancing cloud infrastructure, and driving data-driven innovation while mentoring engineers and ensuring compliance i...

3 days ago

  •   5 - 7 years exp.  •   Staffing

$180K *

Empower clients through expert claims management, ensuring fair coverage interpretation and efficient resolutions while fostering strong relationships and strategic advocacy throughout the property an...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $105K *

Optimize and drive digital media strategies to elevate client success, focusing on Amazon DSP. Build strong relationships, execute growth plans, and leverage data insights to enhance performance acros...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Transform clinical data programming by developing scalable Python solutions, modernizing SAS workflows, and building reusable frameworks to enhance clinical trial data delivery and influence technolog...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $110K *

Shape user experiences by leading research and design initiatives that enhance service delivery and foster a customer-centric culture across federal projects, ensuring impactful solutions that meet us...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Unlock your potential in a rewarding role where you connect with clients, build relationships, and earn competitive compensation in a supportive environment. Enjoy flexibility and mentorship while mak...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Shape the future of identity management by developing and enhancing IAM solutions. Collaborate with teams to implement security measures, automate processes, and address business challenges while stay...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$78K - $95K *

Empower patients by delivering personalized, evidence-based therapy while collaborating with a dynamic team. Enjoy a supportive environment that fosters professional growth and enhances patient care i...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in developing and implementing innovative power generation projects. Collaborate with a multi-discipline team to deliver high-quality mechanical engineering solutions for utility-scale...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$78K - $95K *

Join a team that's dedicated to delivering exceptional patient care while fostering your professional growth. Collaborate with peers in a supportive environment and develop personalized therapy plans...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $122K *

Join a team that's dedicated to managing construction projects of varying complexity, ensuring adherence to timelines, budgets, and quality standards while driving process improvements and vendor nego...

3 days ago

  •   Less than 5 years exp.  •   Transportation

$87K - $157K *

Manage strategic programs and complex projects, ensuring timely delivery while effectively leading cross-functional teams to achieve key business objectives and drive organizational success...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.