Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$80K - $95K *

Join a team that's dedicated to advancing analytical techniques in a dynamic lab environment. Oversee operations, manage staff, and collaborate across departments to enhance quality and efficiency in...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$165K - $180K *

Transform your career by driving new customer acquisition in healthcare. Leverage your expertise to build C-suite relationships and lead complex sales processes, contributing to the growth of a dynami...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Technical Services

$148K - $174K *

Transform the future of global Omni-Commerce payments by leading a dynamic team to innovate and execute a comprehensive strategy that enhances user experience across diverse payment methods and techno...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $92K *

Drive the resolution of technical support escalations as a key Tier 2 expert, leveraging your skills to troubleshoot issues, foster collaboration within teams, and enhance workflows in a dynamic envir...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Technical Services

$110K - $130K *

Transform vulnerability detection by leveraging innovative technology and research. Join a team dedicated to crafting detection logic to identify critical vulnerabilities, ensuring clients stay one st...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$77K - $202K *

Elevate your career by driving operational excellence in manufacturing. Analyze processes, identify bottlenecks, and implement strategies to enhance product development and manufacturing performance w...

3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$123K - $164K *

Lead the charge in electrical engineering for data center projects, ensuring technical quality and scalable standards. Operate autonomously to tackle complex challenges while mentoring junior engineer...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$77K - $202K *

Unlock potential by enhancing manufacturing operations through data analysis, process optimization, and strategic recommendations. Collaborate with clients to improve product development, reduce costs...

3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$82K - $137K *

Transform business insights into actionable data solutions by collaborating with stakeholders, analyzing data quality, and ensuring effective integration of analytical products to drive operational ef...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $210K *

Lead the charge in shaping a global portfolio strategy, driving innovation and AI integration while managing solution development and cross-functional collaboration to achieve client success and marke...

3 days ago

  •   15+ years exp.  •   Information Technology

$88K - $105K *

Champion procurement excellence by leading strategic sourcing projects, managing supplier relationships, and driving operational efficiency in a collaborative environment focused on health and wellnes...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Accelerate progress at transforming data governance frameworks into actionable results. Collaborate with stakeholders to embed standards and ensure alignment across teams in a dynamic, large-scale tra...

3 days ago

  •   Less than 5 years exp.  •   Staffing

$85K - $95K *

Drive a culture of safety across the region by overseeing transportation safety management, conducting audits, and providing training. Collaborate with leadership to ensure compliance with regulations...

3 days ago

  •   Less than 5 years exp.  •   Transportation

$207K - $300K *

Champion the integration of cutting-edge AI solutions, transforming prototypes into production-ready systems while collaborating closely with customers to enhance enterprise capabilities and drive inn...

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$112K - $135K *

Elevate your career by designing and implementing cloud infrastructure solutions in Azure. Collaborate with teams to automate deployments, optimize CI/CD pipelines, and leverage AI tools for enhanced...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's focused on enhancing deposit retention and engagement through strategic initiatives. Lead cross-functional efforts to optimize customer targeting, digital experiences, and performan...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $100K *

Join a team that's dedicated to driving growth through relationship-building and innovative financing solutions. As a Loan Originator, you'll generate new business, manage a robust pipeline, and excee...

Lancaster, PARemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$178K - $307K *

Join a team that's shaping global communications strategies for Immunology. Lead initiatives that enhance stakeholder engagement and reinforce our leadership in the biopharmaceutical landscape while m...

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$178K - $307K *

Shape the future of global immunology communications and public affairs. Lead strategic initiatives, engage stakeholders, and drive alignment across teams to enhance reputation and impact in the bioph...

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$167K - $176K *

Shape the future of design operations by driving program execution, leveraging AI for efficiency, and managing cross-functional partnerships to enhance creative workflows and deliver impactful design...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$95K - $115K *

Drive talent acquisition efforts by managing full-cycle recruiting, collaborating with hiring managers, and enhancing candidate experiences to support organizational growth in a dynamic MedTech enviro...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Join a team that's dedicated to ensuring seamless commercial title transactions. In this remote role, you'll manage complex title clearance issues, collaborate with various stakeholders, and maintain...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Staffing

$178K - $307K *

Transform the future of oncology hematology by leading strategic insights and analytics. Drive growth strategies, collaborate with senior leaders, and leverage data to enhance business impact while fo...

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape innovative marketing strategies for oncology products, collaborating with cross-functional teams to drive impactful promotional tactics and ensure launch readiness, while leveraging insights to...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Optimize your career by managing complex commercial title clearance processes. Collaborate with lenders and attorneys to resolve issues, ensuring timely and accurate transactions in a fast-paced, remo...

Feasterville Trevose, PARemote

3 days ago

  •   Less than 5 years exp.  •   Staffing

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.