Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
Average Salary: $122,395
Senior Director, Global Immunology Communications & Public Affairs
$178K - $307K *
Join a team that's shaping global communications strategies for Immunology. Lead initiatives that enhance stakeholder engagement and reinforce our leadership in the biopharmaceutical landscape while m...
3 days ago
Senior Director, Global Immunology Communications & Public Affairs
$178K - $307K *
Shape the future of global immunology communications and public affairs. Lead strategic initiatives, engage stakeholders, and drive alignment across teams to enhance reputation and impact in the bioph...
3 days ago
Senior Design Program Manager II
$167K - $176K *
Shape the future of design operations by driving program execution, leveraging AI for efficiency, and managing cross-functional partnerships to enhance creative workflows and deliver impactful design...
Reposted 3 days ago
Sr. Talent Acquisition Partner
$95K - $115K *
Drive talent acquisition efforts by managing full-cycle recruiting, collaborating with hiring managers, and enhancing candidate experiences to support organizational growth in a dynamic MedTech enviro...
3 days ago
Commercial Title Clearance Officer
$80K - $120K *
Join a team that's dedicated to ensuring seamless commercial title transactions. In this remote role, you'll manage complex title clearance issues, collaborate with various stakeholders, and maintain...
Reposted 3 days ago
Senior Director, Strategic Insights & Analytics, Oncology Hematology
$178K - $307K *
Transform the future of oncology hematology by leading strategic insights and analytics. Drive growth strategies, collaborate with senior leaders, and leverage data to enhance business impact while fo...
3 days ago
Product Manager, Professional Promotion, Bladder Marketing
$110K - $130K *
Shape innovative marketing strategies for oncology products, collaborating with cross-functional teams to drive impactful promotional tactics and ensure launch readiness, while leveraging insights to...
3 days ago
Commercial Title Clearance Officer
$80K - $120K *
Optimize your career by managing complex commercial title clearance processes. Collaborate with lenders and attorneys to resolve issues, ensuring timely and accurate transactions in a fast-paced, remo...
3 days ago
FS Salesforce Data 360 and AI Architect Manager
$94K - $266K *
Transform enterprise-scale solutions by architecting Data 360 and AI integrations across Financial Services platforms. Lead technical design, governance, and client engagement to drive impactful outco...
3 days ago
Salesforce Cross Skilled Functional Architect - Financial Services
$132K - $302K *
Elevate your career by leading complex Salesforce solutions in Financial Services. Collaborate with diverse teams to design, implement, and mentor while driving innovative AI strategies and ensuring s...
3 days ago
FS Salesforce Data 360 and AI Architect Manager
$94K - $266K *
Join a team that's redefining financial services through innovative Data 360 and AI architecture. Lead enterprise-scale solutions, shape client strategies, and mentor teams while driving impactful res...
3 days ago
Salesforce Cross Skilled Functional Architect - Financial Services
$132K - $302K *
Join a team that's redefining Financial Services solutions by bridging architecture and execution. Lead complex Salesforce implementations, mentor junior architects, and drive innovation across multi...
3 days ago
Staff Software Developer [555]
$167K - $230K *
Develop high-performance software for quantum processors, driving architectural decisions, mentoring teams, and tackling complex challenges. Collaborate with interdisciplinary experts to enhance softw...
Reposted 3 days ago
$170K - $272K *
Advance your career by leading the development of scalable ML systems that drive impactful business outcomes through data science innovation and collaboration with cross-functional teams...
Reposted 3 days ago
Lead Machine Learning Engineer
$220K - $270K *
Join a team that's pushing the boundaries of machine learning in autonomous vehicles. Enhance driving capabilities, lead innovative teams, and drive commercial-scale solutions with cutting-edge techno...
Reposted 3 days ago
$110K - $130K *
Lead the charge in designing and implementing advanced telecommunications systems for complex infrastructure projects. Drive technical excellence and innovation while mentoring engineering staff and c...
3 days ago
$79K - $112K *
Shape the future of HR operations by supporting staffing, onboarding, and employee relations in a dynamic environment, ensuring effective collaboration and consistency across teams to meet business ob...
3 days ago
Territory Account Executive , SMB - Harrisburg, PA
$128K - $205K *
Drive your career with a dynamic sales role focused on building relationships with local restaurateurs. Utilize a consultative approach to understand their needs and deliver tailored solutions, all wh...
Reposted 3 days ago
Physician Assistant, PA-C, or Advanced Practice Nurse, APRN, Gastroenterology - W Webster
$114K - $171K *
Provide comprehensive patient care by assessing, diagnosing, and managing treatment plans. Collaborate with an interdisciplinary team to ensure optimal health outcomes while maintaining accurate docum...
3 days ago
$125K - $150K *
Accelerate your career by leading innovative marketing strategies that drive lead generation and revenue growth. Collaborate with cross-functional teams to enhance brand visibility and cultivate a cul...
3 days ago
Research Engineer (AI + Sports)
$110K - $130K *
Lead cutting-edge AI research in video analysis and game analytics, transforming sports experiences for fans. Collaborate with academic experts to innovate, publish, and bridge the gap between researc...
Reposted 3 days ago
$112K - $134K *
Champion legal excellence by providing guidance on contracts, compliance, and governance. Collaborate with teams to mitigate risks while supporting growth and innovation in a dynamic credit union envi...
3 days ago
$100K - $120K *
Empower healthcare by evaluating medication orders, ensuring accuracy, and collaborating with medical teams to enhance patient care. Join us in delivering safe and effective pharmaceutical services in...
3 days ago
Senior AI Product Engineer, Fullstack
$125K - $225K *
Unlock innovation by building scalable, user-centric applications in TypeScript and React. Collaborate with engineering teams to enhance AI-driven solutions, ensuring top performance in ML observabili...
Reposted 3 days ago
$80K - $95K *
Lead a dynamic Metrology team to ensure compliance and reliability of laboratory instrumentation in a regulated environment. Drive continuous improvement initiatives while mentoring staff and coordina...
3 days ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.