Explore $100K+ Jobs in Oregon

Discover professional opportunities in Oregon with salaries of $100,000 or more. Ladders helps experienced candidates explore vetted roles across the state, from established employers in Portland to opportunities in Salem, Eugene, Bend, and beyond. Browse openings and find positions that match your expertise, career goals, and preferred location.

Find Opportunities Across Oregon

Oregon’s job market spans a range of industries and communities. Search for roles in major hubs such as Portland, Salem, and Eugene, or explore opportunities elsewhere in the state. Use location and role preferences to focus your search on jobs that fit your experience and next career move.

Explore Professional Roles and Industries

High-paying opportunities may be available in areas such as technology, healthcare, finance, engineering, operations, and leadership. Job availability and compensation vary by employer, role, and experience. Review each listing for details about responsibilities, qualifications, location, and pay.

Make Your Oregon Job Search More Focused

Start by identifying the roles and locations that align with your background. Keep your résumé current, highlight measurable accomplishments, and tailor your application to each opportunity. Ladders is designed to help professionals find vetted jobs paying $100,000 or more.

Take the Next Step

Browse current Oregon job listings on Ladders and explore opportunities that support your professional goals. New openings can appear over time, so check back to see the latest roles.

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1,000+

Jobs in Oregon

Average Salary in USD

Average Salary: $110,672

Sort By: Relevance

$285K - $385K *

Lead regulatory due diligence for clinical/commercial assets, assessing risks and strategies for licensing, acquisitions, and partnerships. Collaborate across teams to ensure regulatory integration in...

RemoteRemote

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$189K - $246K *

Lead clinical pharmacology strategies, integrating PK/PD assessments across development phases. Collaborate with cross-functional teams to guide decision-making and regulatory submissions, ensuring al...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$145K - $220K *

Shape the future of Finance by managing AI transformation initiatives, collaborating with stakeholders to identify high-value use cases, and ensuring successful integration of AI solutions within Fina...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Information Technology

$121K - $170K *

Lead the transformation of storage solutions by leveraging deep technical expertise in NetApp Keystone and Storage-as-a-Service. Collaborate with customers to architect tailored solutions that optimiz...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$91K - $128K *

Join a team that's dedicated to empowering educators through impactful training sessions. You'll create engaging content and deliver customized Google for Education engagements, enhancing customer rel...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$176K - $236K *

Lead the charge in global regulatory project management, driving oncology strategies and submissions across regions. Collaborate with cross-functional teams to ensure compliance and timely market acce...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$114K - $154K *

Transform supply chain operations by managing SAP systems and processes, ensuring seamless logistics and distribution support. Drive efficiency and issue resolution across Commercial and Clinical Supp...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$178K - $238K *

Drive impactful oncology drug development by leading program management, optimizing team efficiency, and ensuring strategic alignment across global projects to enhance patient outcomes and organizatio...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Champion integrated supply planning by developing actionable production and procurement strategies. Balance product availability with inventory management while driving cross-functional collaboration...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$105K - $149K *

Drive security excellence by enhancing data protection and detection capabilities. Collaborate with cross-functional teams to implement DLP policies, automate processes, and ensure enterprise systems...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $144K *

Lead high-impact cultural resources projects, mentor talent, and strengthen client relationships while ensuring technical excellence and compliance across archaeological investigations in a collaborat...

6 days ago

  •   5 - 7 years exp.  •   Business Services

$99K - $117K *

Lead strategic commercial initiatives to enhance performance and profitability across a portfolio of franchised hotels. Collaborate with stakeholders to drive revenue growth, optimize market share, an...

United StatesRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Hospitality & Recreation

$115K - $135K *

Drive impactful sales analytics by developing methodologies that enhance performance insights, forecasting, and strategic planning. Collaborate with stakeholders to translate complex data into actiona...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$115K - $175K *

Advance market share by driving strategic growth initiatives within the US Mid-Market and Enterprise carrier segments. Lead a high-performing team to execute regional plans, leveraging deep telecom ex...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Media

$150K - $250K *

Lead the charge in driving sales and building relationships within the roofing industry. As a key liaison, you'll connect with contractors and clients to promote GAF's residential products, ensuring s...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Champion the management of real property portfolios, ensuring compliance and facilitating acquisitions and dispositions. Lead complex negotiations and permitting processes while providing expert guida...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$173K - $211K *

Champion the execution of API strategies, leading teams to deliver secure enterprise APIs and innovative solutions while aligning technology with business goals and fostering a high-performing enginee...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$212K - $318K *

Shape the future of patient-centered outcomes in oncology by leading global strategies for clinical assessments and patient experience data, ensuring impactful evidence generation and regulatory succe...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$121K - $182K *

Manage clinical monitoring activities for multiple trials, providing mentorship and oversight to CRAs. Collaborate with teams to ensure compliance and quality, while addressing site-level issues and e...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $140K *

Unlock potential by bridging technical radio frequency capabilities with US Air Force needs. Collaborate with engineering and business teams to demonstrate and support advanced communication solutions...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$100K - $140K *

Support the U.S. Marine Corps by bridging technical radio capabilities with defense needs. Collaborate with engineering teams to demonstrate and evaluate advanced communication systems in diverse oper...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$100K - $140K *

Join a team that's redefining tactical communications for defense applications. Leverage your engineering expertise to bridge technical capabilities with USSOCOM requirements, supporting innovative so...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$71K - $99K *

Join a team that's dedicated to enhancing clinical practices through effective IT solutions. This role involves training, system maintenance, and collaboration with healthcare professionals to optimiz...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$117K - $150K *

Join a team that's redefining in-vehicle digital experiences. As a Sr. UX/UI Product Designer, you'll lead impactful design projects, mentor talent, and shape the future of mobility for millions of dr...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$78K - $100K *

Champion the evolution of a cutting-edge eCommerce platform by translating business needs into product requirements, collaborating across teams, and ensuring quality releases that enhance user experie...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Oregon?question toggle

    Oregon listings may include professional, technical, managerial, and executive roles across fields such as technology, healthcare, finance, engineering, and operations. Available positions and compensation depend on the employer and role.

  • Which Oregon cities have high-paying job opportunities?question toggle

    Opportunities may be available in Portland, Salem, Eugene, Bend, and other Oregon locations. Browse current listings to see where employers are hiring.

  • Are Oregon jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings that pay $100,000 or more. Review each posting for its qualifications, responsibilities, location, and compensation details.

  • How can I find a high-paying job in Oregon?question toggle

    Search by location and role, review listings that match your experience, and submit a tailored application with a current résumé that highlights relevant skills and accomplishments.