Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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Oncologist Jobs in Iowa

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$208K - $250K *

Inspire excellence in patient care at a leading multi-specialty clinic, where you'll collaborate with a dynamic team of healthcare professionals to enhance services and drive better outcomes in a supp...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Join a team that's dedicated to exceptional patient care and outcomes. Work alongside a large, collaborative group of physicians in a supportive environment that prioritizes your growth and offers com...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Join a team that's redefining internal medicine, collaborating with a skilled group of professionals to deliver high-quality patient care across multiple locations in a supportive, family-friendly atm...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Contribute to a leading multi-specialty clinic by delivering high-quality care as an Internal Medicine Physician. Collaborate with a diverse team to provide excellent patient outcomes in a supportive...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Join a team that's redefining internal medicine with a collaborative, patient-centric approach. Engage with diverse cases, foster professional growth, and enjoy a family-friendly environment in a lead...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a team that's shaping the future of AI solutions by deploying and integrating cutting-edge technologies. Collaborate with customers and engineers to enhance system performance and drive innovatio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$163K - $369K *

Champion negotiation excellence by leading complex deal strategies, fostering client relationships, and ensuring compliance. Collaborate with stakeholders to achieve mutually beneficial outcomes while...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$225K - $253K *

Empower a high-performing sales team to advance post-bariatric hypoglycemia education, translating national strategies into regional plans while fostering strong relationships with healthcare stakehol...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join us to minimize access barriers for patients and providers, executing market access plans across multiple states. Collaborate with healthcare professionals to resolve reimbursement issues and enha...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$97K - $145K *

Lead strategic client coding integration initiatives, ensuring alignment with corporate objectives and regulatory compliance while driving operational excellence and innovation across the revenue cycl...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Empower your career by leading a dynamic team of Client Success Managers, driving customer satisfaction and retention while collaborating cross-functionally to maximize value from our solutions and in...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $110K *

Drive impactful medical economics analysis by extracting and synthesizing data to identify trends, enhance financial performance, and support executive decision-making across healthcare operations and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$247K - $305K *

Support the strategic commercialization of rare disease therapies by leading marketing initiatives, collaborating cross-functionally, and optimizing brand strategies to enhance patient access and enga...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$223K - $233K *

Deliver strategic leadership in biologics process development, overseeing outsourced manufacturing and ensuring alignment with corporate goals while driving technical excellence in late-stage developm...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $216K *

Join a dynamic team to lead technology consulting projects in biopharma, ensuring successful implementation of patient services solutions. Collaborate with clients and cross-functional teams to drive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$225K - $324K *

Accelerate growth by leading global enablement initiatives that empower sellers, engineers, and partners. Drive strategic programs, enhance skills, and ensure readiness for a multi-product platform in...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$80K - $110K *

Transform financial operations by providing analytical support, enhancing reporting processes, and collaborating with cross-functional teams to drive profitability and efficiency in budgeting and fore...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $215K *

Champion strategic sales initiatives by leading a high-performing pod, driving complex SaaS partnerships with top law firms, and fostering executive-level relationships to enhance client engagement an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $110K *

Manage patient care as an Advanced-Practice Provider in a collaborative team, leveraging a large referral network and comprehensive benefits to enhance the well-being of patients in a supportive envir...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Empower transformative telehealth solutions by designing and implementing robust software infrastructure. Join a dynamic team to innovate, automate, and streamline applications, impacting the healthca...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$194K - $242K *

Unlock potential by leading product marketing strategies in GLP-1 and cardiometabolic health. Collaborate with cross-functional teams to enhance buyer clarity and sales effectiveness, while coaching a...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$173K - $320K *

Shape the future of rheumatology by providing strategic medical oversight across clinical trials. Lead the innovation and development of groundbreaking therapies while collaborating with multidiscipli...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive your career with a pivotal role in CMC regulatory affairs, ensuring compliance for biologics and small molecules. Collaborate across teams to prepare high-quality submissions and strategies, imp...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Drive the M&A strategy by leading the full transaction lifecycle, from sourcing to integration. Collaborate with executive leadership to identify growth opportunities that enhance enterprise value and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $160K *

Analyze complex data and drive solutions as a Business Analyst in the public sector. Leverage your expertise in pension systems to identify issues and enhance processes, ensuring effective communicati...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.