Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Oncologist Jobs in Iowa

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$300K - $500K+*

Join a dynamic team as a senior leader driving portfolio performance across the eastern U.S. Oversee regional execution, manage a team of directors, and collaborate on national strategies to enhance b...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by managing complex relationships with multi-hospital systems, guiding clients through intricate reimbursement processes, and influencing strategies that drive partnerships and operat...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$159K - $218K *

Transform sales performance by leading a dynamic team to exceed revenue goals across diverse laboratory solutions in a defined region, fostering customer relationships and driving strategic initiative...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $140K *

Transform your career by leveraging your RCM expertise to drive sales success. Collaborate with cross-functional teams to enhance customer experiences and optimize billing solutions for small to mediu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $135K *

Join a team that's transforming legal transactions with cutting-edge technology. As a Project Attorney, you will lead projects, leverage machine learning tools, and collaborate to drive innovative out...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$71K - $112K *

Drive impactful financial and operational analysis to enhance performance. Collaborate with stakeholders, mentor junior analysts, and present insights that inform strategic decisions across the organi...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $155K *

Accelerate progress at a leading eCommerce firm by driving global business strategy, overseeing P&L, and enhancing marketplace operations. Leverage your expertise in digital marketing and account mana...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$73K - $100K *

Transform patient care by evaluating and treating diverse conditions in an outpatient setting. Collaborate with a dedicated team to enhance recovery and improve quality of life while enjoying a suppor...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$206K - $242K *

Transform external attack capabilities by developing scalable workflows and automating reconnaissance processes. Drive innovation in offensive security, mentor teammates, and contribute to a high-impa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$124K - $171K *

Transform healthcare outcomes by leading large-scale lab diagnostics deals. Drive revenue growth and customer retention through strategic planning, relationship building, and effective execution in a...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$78K - $107K *

Drive financial integrity by managing complex accounting tasks, preparing reports, and influencing departmental strategy. Collaborate with teams to ensure compliance and accuracy while providing valua...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$205K - $256K *

Transform your career by leading Apollo's data strategy, ensuring the highest quality B2B data for GTM success. Drive product vision, collaborate cross-functionally, and enhance customer experiences t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Take ownership of regulatory support for pharmaceutical programs, managing IND and NDA submissions, health authority interactions, and lifecycle maintenance. Collaborate with cross-functional teams to...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$119K - $142K *

Join a team that's redefining digital operations by leading strategic initiatives, enhancing customer experiences, and driving growth in a fast-paced environment. Shape the future of MODAL Digital whi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in driving transformative growth by cultivating strategic relationships and delivering on sales targets within a dynamic healthcare environment, ensuring sustained profitability and ma...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$78K - $156K *

Join a team that's dedicated to enhancing business systems through design, configuration, and support. As a Senior Application Analyst, you'll lead improvements, mentor junior analysts, and ensure sea...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$164K - $305K *

Lead the charge in developing strategic relationships with C-suite executives to drive growth, retention, and value realization across complex health systems, ensuring integrated solutions and measura...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$89K - $134K *

Explore your potential as a key analytical consultant, leveraging data to optimize drug pricing and enhance pharmacy relationships while collaborating across multiple functions to drive strategic grow...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$81K - $90K *

Manage the leave of absence program, ensuring compliance and support for associates. Collaborate with stakeholders to enhance leave experiences and ADA accommodations while maintaining accurate record...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$72K - $116K *

Unlock potential as a mid-level actuarial analyst, applying statistical techniques to enhance insurance pricing, claims analysis, and profitability studies while progressing through the Actuarial Exec...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Lead a dynamic team in delivering high-quality veterinary care while fostering professional growth and collaboration. Enjoy a supportive environment with modern resources and opportunities for mentors...

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$88K - $105K *

Transform patient care in Emergency Medicine by leading clinical practice, enhancing outcomes, and fostering innovation. Collaborate with a multidisciplinary team to implement evidence-based standards...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Unlock potential by managing and expanding relationships with large enterprise clients. Drive strategic account growth and new business development in the SAP ecosystem, ensuring client satisfaction a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $95K *

Transform integrated communications for vaccine brands by managing client relations, strategic planning, and digital engagement. Leverage traditional and digital strategies to drive impactful outcomes...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$93K - $123K *

Join a team that's dedicated to enhancing patient safety and compliance through effective case management. This role involves coordinating complex healthcare cases, collaborating with stakeholders, an...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.