Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Director, Trade Strategy (1 of 2)
$226K - $292K *
Lead strategic trade initiatives by collaborating with cross-functional teams to optimize distribution networks and channel strategies, ensuring alignment with market dynamics and compliance while dri...
2 weeks ago
Senior Manager, Global Regulatory Process and Compliance
$139K - $184K *
Lead regulatory compliance programs ensuring inspection readiness and proactive risk management across cross-functional teams. Monitor compliance health, manage data quality, and drive improvements al...
Reposted 2 weeks ago
$229K - $458K *
Champion strategic growth initiatives in advanced manufacturing, driving business development and forging key partnerships. Collaborate with cross-functional teams to enhance service offerings and mee...
1 week ago
Experienced Clinical Research Associate | Regionally Aligned Across US
$80K - $95K *
Join a dynamic team to oversee clinical research activities, ensuring compliance with regulatory standards and driving site performance. Collaborate with stakeholders to enhance patient safety and dat...
1 week ago
$150K - $180K *
Transform complex legal landscapes into actionable strategies as a Legal Counsel, driving compliance and innovation in payments and fintech. Collaborate with diverse teams to navigate regulations and...
Reposted 3 weeks ago
$160K - $200K *
Unlock potential by partnering with early-stage startups to build robust financial foundations. As a CFO-in-Residence, you'll drive critical finance functions, support fundraising, and shape strategic...
Yesterday
Clinical Supply Chain Site Lead
$110K - $130K *
Champion the clinical supply chain for late-stage oncology trials, ensuring seamless operations and communication between sites, suppliers, and stakeholders. Drive continuous improvement and complianc...
6 days ago
Nurse Practitioner or Physician Assistant (Mobile, AL)
$105K - $130K *
Join a team that's dedicated to providing exceptional primary care to diverse patients. You'll assess health, develop treatment plans, and foster trust while working independently in a supportive envi...
3 days ago
Senior Advisor, Budgeting & Resource Planning
$124K - $153K *
Transform financial management practices by leading budgeting, forecasting, and resource allocation efforts. Collaborate with teams to enhance decision-making and optimize financial systems, ensuring...
3 days ago
Sr. Account Manager - Enterprise
$160K - $190K *
Drive strategic growth by managing key Pharma and Biotech accounts, engaging C-suite executives, and leading expansion sales processes. Collaborate cross-functionally to enhance client experiences and...
1 week ago
$80K - $95K *
Transform nursing services by leading a dedicated team to ensure high-quality care in compliance with regulations. Drive operational excellence and foster a compassionate environment for both long-ter...
3 days ago
Dir Nursing Unit-Crestwood Medical Center-Intensive Care Unit-FT-1st shift
$88K - $105K *
Lead the charge in overseeing unit operations, ensuring quality care delivery, and fostering staff development while managing budgets and maintaining 24-hour accountability for clinical excellence...
Today
Director of SEC Reporting and Technical Accounting
$170K - $210K *
Shape the future of financial reporting by leading SEC compliance and technical accounting. Drive policy development, optimize processes, and collaborate with cross-functional teams to support growth...
3 days ago
Regional Clinical Trial Management Senior Associate
$83K - $113K *
Drive regional clinical study delivery by supporting management and execution of trials, ensuring quality standards and timelines are met. Collaborate with stakeholders and contribute to operational e...
2 days ago
Senior/National Account Director, Market Access
$158K - $250K *
Join a team that's redefining market access strategies in the pharma industry. Leverage your expertise in managed care and payer relationships to drive coverage and reimbursement for innovative therap...
Today
$119K - $179K *
Support the integration and harmonization of clinical data by designing FHIR-compliant models and pipelines, ensuring data accuracy and usability for patient care and research initiatives across the o...
3 weeks ago
Director, Business Applications
$120K - $145K *
Transform the future of business applications by leading strategy, delivery, and operations. Collaborate with multidisciplinary teams to enhance core processes and drive value through effective system...
1 week ago
Account Executive (Enterprise)
$110K - $130K *
Champion the full sales cycle for top enterprise accounts, utilizing a consultative approach to solve complex challenges. Drive impactful relationships with stakeholders, and navigate lengthy processe...
Reposted 4 days ago
$78K - $119K *
Lead the charge in operational excellence by governing product lifecycle standards, translating business needs into actionable specifications, and supporting AI-enabled solutions for continuous improv...
1 week ago
$95K - $115K *
Drive the development of critical contracting strategies and documentation for Army projects. Collaborate with decision-makers in a fast-paced environment, ensuring compliance with DOD and FAR regulat...
1 week ago
Manager, Small Business Advisory
$100K - $120K *
Shape the future of tax strategies by leading our diverse team and managing client relationships. Engage with various industries to deliver tailored solutions and ensure client satisfaction while driv...
Reposted 3 weeks ago
Advanced Practice Provider | Urgent Care | Full-Time
$90K - $110K *
Join a dynamic Urgent Care team, providing high-quality, same-day patient care for a range of acute illnesses and injuries. Collaborate in a supportive environment that values clinical autonomy and qu...
Reposted today
$100K - $130K *
Grow your career with a dynamic role that involves conducting in-depth research across various topics, delivering actionable insights, and collaborating with a high-performing team to tackle complex q...
3 weeks ago
Senior Regional Sales Consultant
$95K - $115K *
Transform healthcare engagement by building relationships with HCPs through digital interactions and telephone conversations, promoting products, and achieving sales goals while ensuring compliance wi...
2 weeks ago
$80K - $95K *
Transform inpatient coding operations by leading a dedicated team to ensure accurate coding, compliance, and timely billing. Collaborate with clinical and administrative staff to enhance financial per...
Yesterday
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.