Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $124,752

Sort By: Relevance

$180K - $220K *

Drive the strategy and roadmap for enterprise-scale Computer Vision solutions, collaborating with internal teams to define requirements and ensure successful adoption of AI models across product portf...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$60K - $119K *

Drive impactful clinical research by leading site contract negotiations and execution. Collaborate with global teams to ensure compliance and efficiency in clinical trial agreements, balancing timelin...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$218K - $350K *

Shape the future of healthcare by leading our subscription business, driving growth and innovation. Collaborate across teams to enhance customer experience and optimize performance, ensuring alignment...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$134K - $210K *

Analyze and drive strategic data analytics projects, ensuring data quality and integrity while supporting executive decision-making and health IT modernization for Tribal Nations. Lead a high-performi...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$118K - $155K *

Drive advanced data analytics initiatives to enhance decision-making and optimize performance. Lead cross-functional projects, ensuring data quality and compliance while mentoring junior analysts in a...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$151K - $226K *

Empower your career by leading avionics safety and software engineering for human-rated spaceflight programs. Collaborate with diverse teams to ensure mission-critical systems meet rigorous standards...

1 week ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$100K - $160K *

Collaborate to develop impactful training programs that drive business transformation, elevate employee capability, and foster continuous learning across the organization, enhancing workforce readines...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Join a team that's dedicated to enhancing digital experiences for a Federal Government program. As a Web Developer, you'll build and maintain websites, ensuring accessibility and performance while col...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Drive material planning and coordination efforts, leading a team to ensure timely and accurate material delivery for project success. Collaborate across disciplines to support project execution and op...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$95K - $115K *

Transform material planning by leading a team to ensure timely and accurate material coordination for project success. Collaborate across disciplines to optimize processes and support project executio...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$105K *

Join a team that's dedicated to providing compassionate end-of-life care for pets. Enjoy a flexible schedule, meaningful interactions, and the support of a caring community while making a lasting impa...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Shape the future of consumer lending by analyzing credit risk and performance data to drive strategic insights for financial institutions, optimizing their underwriting processes and enhancing portfol...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$86K - $115K *

Elevate the quality of healthcare technology by owning test strategies for platform components, enhancing automation, and ensuring stability across releases. Collaborate with cross-functional teams to...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$78K - $95K *

Lead store operations and inspire a high-performing team to elevate client experiences and drive sales in a dynamic retail environment. Champion continuous learning and operational excellence while fo...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$112K - $249K *

Empower innovation by leading product vision and prioritizing client needs. Drive the Scrum process, ensuring delivery of high-value solutions while collaborating with cross-functional teams to enhanc...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$141K - $177K *

Empower the supply chain by leading end-to-end operations, ensuring timely production, optimizing resources, and driving continuous improvement for superior customer service and sustainable growth...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$75K - $90K *

Drive quality improvement initiatives across healthcare settings, enhancing clinical outcomes and operational performance. Collaborate with leadership to optimize patient care and ensure compliance wi...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Shape the future of security by engineering robust controls for endpoints and email. As a Staff Security Engineer, you'll enhance our security posture, mentor peers, and ensure compliance in a regulat...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Unlock potential by leading the architectural strategy for AI systems in next-gen computing. Shape the roadmap for AI inference and training across immersive devices, driving cross-functional collabor...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$115K - $207K *

Optimize multi-functional project teams while managing complex technology projects. Drive customer relationships, ensuring alignment with tech roadmaps and enhancing service visibility. Lead initiativ...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$115K - $130K *

Join a team that's committed to enhancing regulatory compliance through strategic initiatives, robust IT control design, and effective collaboration across business units to ensure adherence to indust...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$122K - $270K *

Lead the charge in transforming banking through agentic commerce and digital ecosystems. Drive strategic initiatives, modernize platforms, and enhance client engagement while managing multidisciplinar...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$122K - $270K *

Accelerate progress at the forefront of digital transformation in banking. Lead multidisciplinary teams to modernize financial product distribution and enhance customer experiences through AI-driven e...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$122K - $270K *

Help us lead transformative digital strategies for banking clients, modernizing product distribution and enhancing customer experiences through AI-driven ecosystems. Collaborate with multidisciplinary...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$122K - $317K *

Join a team that's redefining enterprise productivity and performance. Collaborate with senior executives to drive cost transformation, enhance operational efficiency, and create sustainable value thr...

1 week ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.