Find $100K+ Professional Jobs in Ohio

Explore high-paying professional opportunities across Ohio with Ladders. Browse vetted roles with salaries of $100,000 or more in major employment centers such as Columbus, Cleveland, Cincinnati, Dayton, and Akron. Whether you’re seeking your next leadership position or a specialized role, discover openings across a range of industries and experience levels.

Explore Ohio’s Major Job Markets

Ohio’s diverse economy creates opportunities in metropolitan hubs and communities throughout the state. Search roles in Columbus, a center for business, healthcare, government, and technology; Cleveland, with opportunities in healthcare, manufacturing, finance, and professional services; and Cincinnati, known for corporate headquarters, consumer goods, logistics, and healthcare. You can also explore positions in Dayton, Akron, Toledo, and other Ohio locations.

Industries and Career Paths

Ohio employers hire experienced professionals across industries including healthcare, technology, engineering, manufacturing, finance, sales, operations, and executive leadership. Available positions and compensation vary by employer, role, location, and qualifications. Use search filters to focus on the fields and opportunities that match your career goals.

Find the Right Ohio Opportunity

Review job requirements, responsibilities, location, and compensation details to identify roles that fit your experience. Keep your profile and résumé current, set up job alerts, and check back often to find newly posted opportunities. Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore their next career move in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $125,313

Sort By: Relevance

$110K - $130K *

Elevate customer success by guiding clients through onboarding and product adoption. Serve as a trusted advisor, ensuring maximum value from solutions while advocating for customer needs within the or...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$88K - $105K *

Lead the charge in operational excellence by managing a dynamic team focused on continuous improvement, customer satisfaction, and production goals in a Circuit Breaker and Switchgear repair facility...

4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$80K - $95K *

Drive operational excellence and customer satisfaction by leading continuous improvement initiatives and managing production goals in a dynamic repair facility. Collaborate with teams to enhance quali...

4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $130K *

Unlock potential by leading systems engineering efforts for NASA's deep-space nuclear-electric propulsion mission, focusing on requirements development and integration for the SR-1 Freedom Nuclear Pow...

4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$80K - $100K *

Optimize data-driven strategies to enhance customer engagement and retention. Collaborate with operations to implement scalable solutions in a dynamic startup environment, making a significant impact...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Transportation

$200K - $220K *

Lead product management for an innovative infrastructure automation platform, driving strategy and vision while managing a team of senior product managers. Collaborate cross-functionally to enhance cu...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$85K - $100K *

Elevate the standard of care by leading a dedicated team in providing comprehensive primary care services to Veterans. Utilize your medical expertise to diagnose, treat, and coordinate care while ensu...

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Help us drive client success by managing campaigns and relationships. You'll oversee a portfolio, lead strategy discussions, optimize Meta campaigns, and ensure client satisfaction through proactive c...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Champion the integration and enhancement of PeopleSoft systems for State governments, bridging technical and functional needs. Collaborate with stakeholders to optimize applications, ensuring seamless...

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$118K - $180K *

Drive quality assurance excellence in heavy industrial construction projects, ensuring compliance and safety standards are met throughout all phases. Collaborate with contractors to enhance performanc...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Technical Services

$185K - $215K *

Take ownership of analytical development initiatives, ensuring compliance, accuracy, and high-quality documentation for multiple projects. Collaborate closely with internal teams and external partners...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$275K - $350K *

Lead the charge in building a subscription research business, driving sales and market strategy across energy, trading, and institutional sectors. Collaborate with analysts to tailor offerings and est...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$213K - $335K *

Optimize legal operations by leveraging technology and AI to enhance efficiency, drive strategic projects, and foster collaboration within a fast-paced healthcare tech environment. Lead a team to impl...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $140K *

Elevate your career by managing day-to-day accounting operations, ensuring compliance with U.S. GAAP, and collaborating across departments to support financial reporting and audits in a dynamic pharma...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$147K - $221K *

Drive efficient dispute resolution as a key legal partner, managing complex litigation and advising cross-functional teams. Collaborate closely with stakeholders to mitigate risks and enhance litigati...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $160K *

Optimize patient-facing and internal tools by delivering seamless integrations and AI-driven features. Take ownership of end-to-end development in a fast-paced telehealth environment focused on men's...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$115K *

Elevate sales performance by managing a high-performing territory, building key industry relationships, and delivering tailored engineered solutions across multiple sectors, driving revenue growth and...

4 days ago

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Join a team that's redefining DME resupply operations by leading a global, remote call center. Drive revenue growth, optimize performance, and ensure compliance while managing a diverse workforce to e...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's focused on optimizing Active Directory and Group Policy management. You'll implement automation, manage Windows Server lifecycles, and enhance operational efficiency through scripti...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $170K *

Lead the charge in integrating AI capabilities across enterprise platforms, enhancing digital services for Veterans. Collaborate with teams to implement innovative solutions while ensuring security an...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$133K - $210K *

Transform internal communications by connecting employees to strategy and culture. Lead a team, advise executives, and drive effective communication strategies that enhance organizational alignment an...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$100K - $120K *

Lead the charge in managing supply chain and logistics operations, ensuring accurate inventory control and timely shipments. Collaborate with internal and external partners to optimize processes and s...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Elevate clinical research by monitoring trials, ensuring compliance with protocols and regulations. Collaborate with investigators to achieve study goals in dermatology and rheumatology, while working...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $159K *

Elevate our global governance, risk, and compliance programme by leading risk assessments, policy governance, and audit support. Collaborate with cross-functional teams to ensure compliance with ISO 2...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $177K *

Elevate financial oversight and contract management for Transmission Field Services. Lead budget management, process improvements, and training initiatives while ensuring compliance and accuracy in fi...

4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, management, executive, and specialized positions in fields such as healthcare, technology, engineering, manufacturing, finance, sales, and operations. Roles and salaries vary by employer and qualifications.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, Dayton, Akron, Toledo, and other Ohio communities. Availability changes as employers post and fill positions.

  • Are the Ohio jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Review each listing for its specific compensation and requirements.

  • How can I find a suitable job in Ohio?question toggle

    Search by location, job title, industry, or other relevant filters. Compare the qualifications, responsibilities, location, and compensation listed for each role, and keep your résumé and profile up to date.